IN2014MN01551A - - Google Patents
Info
- Publication number
- IN2014MN01551A IN2014MN01551A IN1551MUN2014A IN2014MN01551A IN 2014MN01551 A IN2014MN01551 A IN 2014MN01551A IN 1551MUN2014 A IN1551MUN2014 A IN 1551MUN2014A IN 2014MN01551 A IN2014MN01551 A IN 2014MN01551A
- Authority
- IN
- India
- Prior art keywords
- geranylgeranylacetone
- composition
- cells
- mixture
- various retina
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/121—Ketones acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Abstract
An ophthalmic composition containing a geranylgeranylacetone selected from (a) (b) or (c) mentioned below protects various retina cells from degeneration disorder or annihilation and significantly promotes the survival of said cells. Therefore said composition exerts a dramatic effect in the prevention amelioration or treatment of various retina disorders. Moreover the composition is less likely to become cloudy when being stored. (a) A mixture of 5E 9E 13E geranylgeranylacetone and 5Z 9E 13E geranylgeranylacetone the mixture containing 80 weight% or more of the 5E 9E 13E geranylgeranylacetone; (b) only 5E 9E 13E geranylgeranylacetone; (c) only 5Z 9E 13E geranylgeranylacetone.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012040779 | 2012-02-27 | ||
PCT/JP2013/054779 WO2013129317A1 (en) | 2012-02-27 | 2013-02-25 | Ophthalmic composition containing geranylgeranylacetone |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014MN01551A true IN2014MN01551A (en) | 2015-05-08 |
Family
ID=49082514
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN1551MUN2014 IN2014MN01551A (en) | 2012-02-27 | 2013-02-25 |
Country Status (7)
Country | Link |
---|---|
US (2) | US20130303624A1 (en) |
JP (2) | JP5358748B1 (en) |
CN (1) | CN104136018A (en) |
HK (1) | HK1200112A1 (en) |
IN (1) | IN2014MN01551A (en) |
TW (1) | TWI564006B (en) |
WO (1) | WO2013129317A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI564006B (en) * | 2012-02-27 | 2017-01-01 | 樂敦製藥股份有限公司 | Ophthalmic composition comprising geranylgeranylacetone |
JP5483513B1 (en) * | 2013-02-19 | 2014-05-07 | ロート製薬株式会社 | Mucosal application agent for prevention, improvement, or treatment of retinal diseases |
JP5687395B2 (en) * | 2013-02-19 | 2015-03-18 | ロート製薬株式会社 | Mucosal application agent for prevention, improvement, or treatment of retinal diseases |
WO2015029925A1 (en) * | 2013-08-26 | 2015-03-05 | ロート製薬株式会社 | Prophylactic, ameliorative, or therapeutic agent for retinopathy |
CN110893180A (en) * | 2018-09-12 | 2020-03-20 | 厦门信力康生物技术有限公司 | Application of teprenone and derivatives thereof in preparing drugs for treating drug addiction and preventing relapse |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06192073A (en) * | 1992-12-24 | 1994-07-12 | Eisai Co Ltd | Cell differentiation-inducing agent |
JPH08133967A (en) * | 1994-11-02 | 1996-05-28 | Eisai Co Ltd | Agent for treating dry eye |
JP2000319170A (en) * | 1999-03-05 | 2000-11-21 | Eisai Co Ltd | Teprenone-containing eye lotion |
US20050009772A1 (en) * | 2003-05-06 | 2005-01-13 | The Regents Of The University Of California | Methods and compositions for the treatment of glaucoma and other retinal diseases |
JP5027425B2 (en) * | 2006-02-17 | 2012-09-19 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Channel disease therapeutic agent containing geranylgeranylacetone as an active ingredient |
CN1903188B (en) * | 2006-08-03 | 2011-07-27 | 首都医科大学附属北京同仁医院 | Application of teprenone for preparing medicine for treating and/or preventing glaucoma |
CA2806238A1 (en) * | 2010-09-01 | 2012-03-08 | Coyote Pharmaceuticals, Inc. | Methods for treating neurodegenerative diseases |
CN102627539B (en) * | 2011-10-19 | 2014-04-16 | 利安隆博华(天津)医药化学有限公司 | Method for producing all trans-teprenone |
TWI564006B (en) * | 2012-02-27 | 2017-01-01 | 樂敦製藥股份有限公司 | Ophthalmic composition comprising geranylgeranylacetone |
-
2013
- 2013-02-25 TW TW102106509A patent/TWI564006B/en not_active IP Right Cessation
- 2013-02-25 CN CN201380011324.9A patent/CN104136018A/en active Pending
- 2013-02-25 US US13/775,524 patent/US20130303624A1/en not_active Abandoned
- 2013-02-25 JP JP2013510416A patent/JP5358748B1/en active Active
- 2013-02-25 IN IN1551MUN2014 patent/IN2014MN01551A/en unknown
- 2013-02-25 WO PCT/JP2013/054779 patent/WO2013129317A1/en active Application Filing
- 2013-07-12 JP JP2013146978A patent/JP2013213050A/en active Pending
-
2014
- 2014-08-15 US US14/460,564 patent/US20140350119A1/en not_active Abandoned
-
2015
- 2015-01-20 HK HK15100637.2A patent/HK1200112A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
JPWO2013129317A1 (en) | 2015-07-30 |
JP5358748B1 (en) | 2013-12-04 |
CN104136018A (en) | 2014-11-05 |
HK1200112A1 (en) | 2015-07-31 |
US20140350119A1 (en) | 2014-11-27 |
WO2013129317A1 (en) | 2013-09-06 |
JP2013213050A (en) | 2013-10-17 |
TWI564006B (en) | 2017-01-01 |
TW201340963A (en) | 2013-10-16 |
US20130303624A1 (en) | 2013-11-14 |
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