IN2014KN00742A - - Google Patents

Info

Publication number
IN2014KN00742A
IN2014KN00742A IN742KON2014A IN2014KN00742A IN 2014KN00742 A IN2014KN00742 A IN 2014KN00742A IN 742KON2014 A IN742KON2014 A IN 742KON2014A IN 2014KN00742 A IN2014KN00742 A IN 2014KN00742A
Authority
IN
India
Prior art keywords
tbi
methods
tsi
compositions
therapeutics
Prior art date
Application number
Inventor
Yunsheng Li
Paul D Olivo
Jaekyung Kim
Original Assignee
Quidel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quidel Corp filed Critical Quidel Corp
Publication of IN2014KN00742A publication Critical patent/IN2014KN00742A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/723—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/046—Thyroid disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Compositions and methods for detecting thyroid hormone blocking immunoglobulin (TBI) are disclosed. The methods are sensitive and specific for TBI and may be used for the dual detection of both TBI and TSI. The compositions and methods are useful for the diagnosis of diseases that are associated with the presence of TBI and/or TSI for monitoring the progress of disease and/or treatment regimens therapeutics vaccines etc. and for assisting clinicians in making treatment decisions.
IN742KON2014 2011-09-09 2011-09-09 IN2014KN00742A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/228,705 US8986937B2 (en) 2011-09-09 2011-09-09 Compositions and methods for detecting autoantibodies
PCT/US2011/050976 WO2013036239A1 (en) 2011-09-09 2011-09-09 Compositions and methods for detecting autoantibodies

Publications (1)

Publication Number Publication Date
IN2014KN00742A true IN2014KN00742A (en) 2015-10-02

Family

ID=47830166

Family Applications (1)

Application Number Title Priority Date Filing Date
IN742KON2014 IN2014KN00742A (en) 2011-09-09 2011-09-09

Country Status (9)

Country Link
US (3) US8986937B2 (en)
EP (1) EP2753928B1 (en)
JP (1) JP5908590B2 (en)
KR (1) KR101872060B1 (en)
CN (1) CN103975239B (en)
DK (1) DK2753928T3 (en)
IN (1) IN2014KN00742A (en)
PL (1) PL2753928T3 (en)
WO (1) WO2013036239A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020050208A1 (en) * 2018-09-05 2020-03-12 ヤマサ醤油株式会社 Method and kit for rapid measurement of autoantibody activity with respect to tsh receptor
WO2020185926A1 (en) * 2019-03-12 2020-09-17 Quidel Corporation Compositions, kits, and methods for detecting autoantibodies
JP7212955B2 (en) * 2020-12-28 2023-01-26 ヤマサ醤油株式会社 Methods and kits for assaying activity of thyroid-stimulating hormone receptor-inhibiting autoantibodies
CN113686841B (en) * 2021-09-01 2023-06-30 北京利德曼生化股份有限公司 Kit for quantitatively detecting thyroxine binding force, preparation method and detection method thereof
WO2023214183A2 (en) 2022-05-06 2023-11-09 Antibody Analytics Limited Chemically induced proximity systems

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999014336A2 (en) * 1997-09-19 1999-03-25 Promega Corporation Thermostable luciferases and methods of production
US6747139B1 (en) 1997-11-05 2004-06-08 Quest Diagnostics Investments, Inc. Nucleic acid encoding human thyrotropin receptor
US8293879B2 (en) * 2000-03-30 2012-10-23 Diagnostic Hybrids, Inc. Methods of using chimeric receptors to identify autoimmune disease
US8563257B2 (en) * 2000-03-30 2013-10-22 Diagnostic Hybrids, Inc. Sensitive and rapid methods of using chimeric receptors to identify autoimmune disease and assess disease severity
GB0516527D0 (en) * 2005-08-11 2005-09-21 Arpi Matossian Rogers Peptides
WO2007057778A2 (en) 2005-11-21 2007-05-24 Dr. Fenning Biomed Gmbh Recombinant polypeptides and methods for detecting and/or quantifying autoantibodies against tsh receptor
US8840891B2 (en) * 2007-02-15 2014-09-23 Rsr Limited Human monoclonal antibodies to the thyrotropin receptor which act as antagonists
TW200918058A (en) * 2007-08-31 2009-05-01 Organon Nv TSH receptor antagonizing tetrahydroquinoline compounds
US7799532B2 (en) * 2008-11-12 2010-09-21 Hemopet Detection and measurement of thyroid hormone autoantibodies
ES2545759T3 (en) * 2008-12-24 2015-09-15 Rsr Limited Human anti-TSHR antibodies

Also Published As

Publication number Publication date
JP5908590B2 (en) 2016-04-26
KR101872060B1 (en) 2018-06-27
WO2013036239A1 (en) 2013-03-14
PL2753928T3 (en) 2018-07-31
US20200340991A1 (en) 2020-10-29
US8986937B2 (en) 2015-03-24
CN103975239A (en) 2014-08-06
KR20140084022A (en) 2014-07-04
EP2753928A1 (en) 2014-07-16
US20130065252A1 (en) 2013-03-14
JP2014529993A (en) 2014-11-17
EP2753928A4 (en) 2015-05-27
CN103975239B (en) 2016-08-24
EP2753928B1 (en) 2018-02-07
US20150233914A1 (en) 2015-08-20
DK2753928T3 (en) 2018-05-22

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