IN2014DN09779A - - Google Patents
Info
- Publication number
- IN2014DN09779A IN2014DN09779A IN9779DEN2014A IN2014DN09779A IN 2014DN09779 A IN2014DN09779 A IN 2014DN09779A IN 9779DEN2014 A IN9779DEN2014 A IN 9779DEN2014A IN 2014DN09779 A IN2014DN09779 A IN 2014DN09779A
- Authority
- IN
- India
- Prior art keywords
- osteoporosis
- vitamin
- per day
- bone tissue
- drone brood
- Prior art date
Links
- 210000000988 bone and bone Anatomy 0.000 abstract 4
- 229930003231 vitamin Natural products 0.000 abstract 4
- 239000011782 vitamin Substances 0.000 abstract 4
- 229940088594 vitamin Drugs 0.000 abstract 4
- 235000013343 vitamin Nutrition 0.000 abstract 4
- 244000144987 brood Species 0.000 abstract 3
- 208000010392 Bone Fractures Diseases 0.000 abstract 2
- 208000001164 Osteoporotic Fractures Diseases 0.000 abstract 2
- 229940043430 calcium compound Drugs 0.000 abstract 2
- 150000001674 calcium compounds Chemical class 0.000 abstract 2
- 239000002207 metabolite Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000011321 prophylaxis Methods 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 150000003722 vitamin derivatives Chemical class 0.000 abstract 2
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 229930003316 Vitamin D Natural products 0.000 abstract 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
- 239000003098 androgen Substances 0.000 abstract 1
- 230000033558 biomineral tissue development Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 235000019166 vitamin D Nutrition 0.000 abstract 1
- 239000011710 vitamin D Substances 0.000 abstract 1
- 150000003710 vitamin D derivatives Chemical class 0.000 abstract 1
- 229940046008 vitamin d Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Insects & Arthropods (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A method for the prophylaxis and treatment of osteoporosis and bone fractures and a preparation for the prophylaxis and treatment of osteoporosis and bone fractures relate to medicine , in particular to means for preventive action in the event of conditions associated with various forms of osteoporosis. The method is characterized by a dose of from 10 mg to 1000 mg per day of drone brood and a vitamin or vitamins of group D and/or active metabolites thereof of from 50 ME to 1000 000 ME per day , and a calcium compound of from 25 mg to 3000 mg per day , with simultaneous administration to an organism within a 24 -hour period, where the preparation , consisting of from 10 mg to 1000 mg of drone brood, vitamin or vitamins of group D , and/or active metabolites thereof of from 50 ME to 1000 000 ME , and a calcium compound of from 25 mg to 3000 mg, can be realized in powdery , tablet or capsule form. Implementation of the invention provides for the achievement of the technical result which is envisaged by the applicant which makes it possible to eliminate or reduce imbalance in the mineralization of various sections of bone tissue. The use of the claimed agent boosts the mechanism for uniformly restoring the mineral density of the bones , and the use of drone brood together with vitamin D is directed towards additional boosting of the remodelling of diseased sections of bone tissue and towards retaining bone tissue by maintaining the androgen level.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2012115653/15A RU2498811C1 (en) | 2012-04-19 | 2012-04-19 | Method for prevention and treatment of osteoporosis and bone fractures, and preparation for prevention and treatment of osteoporosis and bone fractures |
| PCT/RU2012/000689 WO2013157984A1 (en) | 2012-04-19 | 2012-08-21 | preparation and method for the prophylaxis and treatment of osteoporosis and bone fractures |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN09779A true IN2014DN09779A (en) | 2015-07-31 |
Family
ID=49383802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN9779DEN2014 IN2014DN09779A (en) | 2012-04-19 | 2014-11-19 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20150174176A1 (en) |
| EP (1) | EP2875820A4 (en) |
| JP (1) | JP6286418B2 (en) |
| CN (1) | CN104379154A (en) |
| AU (1) | AU2012377478B2 (en) |
| BR (1) | BR112014025973B1 (en) |
| CA (1) | CA2870828C (en) |
| EA (1) | EA026534B1 (en) |
| IL (1) | IL235171B (en) |
| IN (1) | IN2014DN09779A (en) |
| RU (1) | RU2498811C1 (en) |
| UA (1) | UA111280C2 (en) |
| WO (1) | WO2013157984A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2548776C2 (en) * | 2013-01-11 | 2015-04-20 | Общество С Ограниченной Ответственностью "Парафарм" | Method and medication for acceleration of bone fracture consolidation |
| RU2549461C2 (en) * | 2013-01-11 | 2015-04-27 | Общество С Ограниченной Ответственностью "Парафарм" | Method and medication for treating arthritis and arthrosis |
| RU2564111C9 (en) * | 2013-07-03 | 2016-03-20 | Общество С Ограниченной Ответственностью "Парафарм" | Application of adsorbed drone brood homogenate and group d vitamins and/or their active metabolites for prevention and treatment of acute respiratory diseases and flu |
| RU2593018C1 (en) * | 2015-10-28 | 2016-07-27 | Общество С Ограниченной Ответственностью "Парафарм" | Method of treating osteoarthrosis |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743596A (en) * | 1987-06-16 | 1988-05-10 | Lapin Alfred R | Anti-arthritic preparation |
| CN1101684C (en) * | 1997-07-24 | 2003-02-19 | 薛大权 | Bee pupa calcium preparation |
| WO2002013832A1 (en) * | 2000-08-17 | 2002-02-21 | Chugai Seiyaku Kabushiki Kaisha | Remedial agent for osteoporosis |
| JP2007525953A (en) * | 2003-06-06 | 2007-09-13 | ワイス | Methods and materials for identifying substances that modulate bone remodeling, and substances identified thereby |
| JP5509504B2 (en) * | 2008-02-13 | 2014-06-04 | ディーエスエム アイピー アセッツ ビー．ブイ． | Combination of 25-hydroxy-vitamin D3 and vitamin D3 to improve bone mineral density and treat osteoporosis |
| FR2945748A1 (en) * | 2009-05-20 | 2010-11-26 | Debregeas Et Associes Pharma | DRUG BASED ON CALCIUM AND VITAMIN D. |
| RU2412616C1 (en) * | 2009-11-30 | 2011-02-27 | Общество С Ограниченной Ответственностью "Парафарм" | Biologically active food supplement for osteoporosis prophylactics |
| RU2466732C1 (en) * | 2011-05-31 | 2012-11-20 | Общество С Ограниченной Ответственностью "Парафарм" | Method for filling cavitary lesions in metaphyseal (trabecular) bone segments with calcium and preventing calcium excretion |
| RU2497533C1 (en) * | 2012-04-19 | 2013-11-10 | Общество С Ограниченной Ответственностью "Парафарм" | Method and preparation for preventing and treating atypical osteoporosis with normal or increased bone mineralisation with cavitary lesions in trabecular bones (and related conditions in overweight and metabolic syndrome) |
-
2012
- 2012-04-19 RU RU2012115653/15A patent/RU2498811C1/en active
- 2012-08-21 CA CA2870828A patent/CA2870828C/en active Active
- 2012-08-21 UA UAA201412409A patent/UA111280C2/en unknown
- 2012-08-21 CN CN201280074010.9A patent/CN104379154A/en active Pending
- 2012-08-21 EA EA201401157A patent/EA026534B1/en unknown
- 2012-08-21 WO PCT/RU2012/000689 patent/WO2013157984A1/en not_active Ceased
- 2012-08-21 EP EP12874726.8A patent/EP2875820A4/en not_active Withdrawn
- 2012-08-21 BR BR112014025973-9A patent/BR112014025973B1/en active IP Right Grant
- 2012-08-21 AU AU2012377478A patent/AU2012377478B2/en not_active Ceased
- 2012-08-21 US US14/395,482 patent/US20150174176A1/en active Pending
- 2012-08-21 JP JP2015506935A patent/JP6286418B2/en not_active Expired - Fee Related
-
2014
- 2014-10-19 IL IL235171A patent/IL235171B/en active IP Right Grant
- 2014-11-19 IN IN9779DEN2014 patent/IN2014DN09779A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2498811C1 (en) | 2013-11-20 |
| US20150174176A1 (en) | 2015-06-25 |
| JP6286418B2 (en) | 2018-02-28 |
| BR112014025973A2 (en) | 2017-06-27 |
| EA026534B1 (en) | 2017-04-28 |
| EP2875820A4 (en) | 2016-01-27 |
| AU2012377478B2 (en) | 2017-07-06 |
| WO2013157984A1 (en) | 2013-10-24 |
| CN104379154A (en) | 2015-02-25 |
| EP2875820A1 (en) | 2015-05-27 |
| IL235171B (en) | 2019-09-26 |
| AU2012377478A1 (en) | 2014-12-11 |
| CA2870828C (en) | 2019-01-15 |
| IL235171A0 (en) | 2014-12-31 |
| CA2870828A1 (en) | 2013-10-24 |
| JP2015514755A (en) | 2015-05-21 |
| AU2012377478A8 (en) | 2014-12-18 |
| BR112014025973B1 (en) | 2021-09-28 |
| UA111280C2 (en) | 2016-04-11 |
| EA201401157A1 (en) | 2015-05-29 |
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