IN2014DN08260A - - Google Patents

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Publication number
IN2014DN08260A
IN2014DN08260A IN8260DEN2014A IN2014DN08260A IN 2014DN08260 A IN2014DN08260 A IN 2014DN08260A IN 8260DEN2014 A IN8260DEN2014 A IN 8260DEN2014A IN 2014DN08260 A IN2014DN08260 A IN 2014DN08260A
Authority
IN
India
Prior art keywords
telaprevir
solvate
preparation
pharmaceutically acceptable
acceptable salt
Prior art date
Application number
Inventor
Wolfgang Felzmann
Stefanie Brunner
Thorsten Wilhelm
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IN2014DN08260A publication Critical patent/IN2014DN08260A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Abstract

The invention relates to a process for the preparation of telaprevir or a pharmaceutically acceptable salt or solvate thereof wherein the process requires a smaller number of process steps and/or does not require the use of toxic and instable compounds compared to the known processes. Another embodiment refers to telaprevir or a pharmaceutically acceptable salt or solvate thereof as well as to intermediate products for preparation of the same wherein the afore mentioned products are obtained by the process described herein.
IN8260DEN2014 2012-03-16 2013-03-15 IN2014DN08260A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12159923 2012-03-16
PCT/EP2013/055397 WO2013135870A1 (en) 2012-03-16 2013-03-15 Process for the synthesis of telaprevir, or pharmaceutically acceptable salts or solvates as well as intermediate products thereof

Publications (1)

Publication Number Publication Date
IN2014DN08260A true IN2014DN08260A (en) 2015-05-15

Family

ID=47884350

Family Applications (1)

Application Number Title Priority Date Filing Date
IN8260DEN2014 IN2014DN08260A (en) 2012-03-16 2013-03-15

Country Status (4)

Country Link
US (1) US20150038677A1 (en)
EP (1) EP2825534A1 (en)
IN (1) IN2014DN08260A (en)
WO (1) WO2013135870A1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030017569A (en) * 2000-06-28 2003-03-03 테바 파마슈티컬 인더스트리즈 리미티드 Carvedilol
PT1934179E (en) 2005-08-19 2010-07-12 Vertex Pharma Processes and intermediates
US8399615B2 (en) 2005-08-19 2013-03-19 Vertex Pharmaceuticals Incorporated Processes and intermediates

Also Published As

Publication number Publication date
WO2013135870A1 (en) 2013-09-19
US20150038677A1 (en) 2015-02-05
EP2825534A1 (en) 2015-01-21

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