IN2014DN07588A - - Google Patents
Info
- Publication number
 - IN2014DN07588A IN2014DN07588A IN7588DEN2014A IN2014DN07588A IN 2014DN07588 A IN2014DN07588 A IN 2014DN07588A IN 7588DEN2014 A IN7588DEN2014 A IN 7588DEN2014A IN 2014DN07588 A IN2014DN07588 A IN 2014DN07588A
 - Authority
 - IN
 - India
 - Prior art keywords
 - guest molecule
 - composite
 - low density
 - density polyethylene
 - polymer host
 - Prior art date
 
Links
- -1 polyethylene terephthalate Polymers 0.000 abstract 5
 - 239000002131 composite material Substances 0.000 abstract 3
 - 229930040373 Paraformaldehyde Natural products 0.000 abstract 2
 - 239000004743 Polypropylene Substances 0.000 abstract 2
 - 239000004205 dimethyl polysiloxane Substances 0.000 abstract 2
 - 229920001684 low density polyethylene Polymers 0.000 abstract 2
 - 239000004702 low-density polyethylene Substances 0.000 abstract 2
 - 229920000435 poly(dimethylsiloxane) Polymers 0.000 abstract 2
 - 229920003229 poly(methyl methacrylate) Polymers 0.000 abstract 2
 - 229920001610 polycaprolactone Polymers 0.000 abstract 2
 - 239000004632 polycaprolactone Substances 0.000 abstract 2
 - 239000005020 polyethylene terephthalate Substances 0.000 abstract 2
 - 229920000139 polyethylene terephthalate Polymers 0.000 abstract 2
 - 229920000642 polymer Polymers 0.000 abstract 2
 - 239000004926 polymethyl methacrylate Substances 0.000 abstract 2
 - 229920006324 polyoxymethylene Polymers 0.000 abstract 2
 - 229920001155 polypropylene Polymers 0.000 abstract 2
 - 229920001343 polytetrafluoroethylene Polymers 0.000 abstract 2
 - 239000004810 polytetrafluoroethylene Substances 0.000 abstract 2
 - KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
 - 229920010126 Linear Low Density Polyethylene (LLDPE) Polymers 0.000 abstract 1
 - 239000008280 blood Substances 0.000 abstract 1
 - 210000004369 blood Anatomy 0.000 abstract 1
 - 210000003709 heart valve Anatomy 0.000 abstract 1
 - 229920002674 hyaluronan Polymers 0.000 abstract 1
 - 229960003160 hyaluronic acid Drugs 0.000 abstract 1
 - 229920002635 polyurethane Polymers 0.000 abstract 1
 - 239000004814 polyurethane Substances 0.000 abstract 1
 - 230000002792 vascular Effects 0.000 abstract 1
 
Classifications
- 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
 - A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
 - A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
 - A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
 - A61L17/06—At least partially resorbable materials
 - A61L17/10—At least partially resorbable materials containing macromolecular materials
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
 - A61L27/14—Macromolecular materials
 - A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
 - A61L27/14—Macromolecular materials
 - A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
 - A61L27/14—Macromolecular materials
 - A61L27/20—Polysaccharides
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
 - A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
 - A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
 - A61L27/54—Biologically active materials, e.g. therapeutic substances
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
 - A61L29/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
 - A61L29/126—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
 - A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
 - A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
 - A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
 - A61L31/129—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing macromolecular fillers
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
 - A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
 - A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
 - A61L2300/23—Carbohydrates
 - A61L2300/236—Glycosaminoglycans, e.g. heparin, hyaluronic acid, chondroitin
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
 - A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
 - A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
 - A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
 - A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
 - A61L2430/00—Materials or treatment for tissue regeneration
 - A61L2430/20—Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves
 
 
Landscapes
- Health & Medical Sciences (AREA)
 - Chemical & Material Sciences (AREA)
 - Life Sciences & Earth Sciences (AREA)
 - Veterinary Medicine (AREA)
 - Public Health (AREA)
 - General Health & Medical Sciences (AREA)
 - Animal Behavior & Ethology (AREA)
 - Epidemiology (AREA)
 - Medicinal Chemistry (AREA)
 - Engineering & Computer Science (AREA)
 - Transplantation (AREA)
 - Oral & Maxillofacial Surgery (AREA)
 - Dermatology (AREA)
 - Materials Engineering (AREA)
 - Composite Materials (AREA)
 - Vascular Medicine (AREA)
 - Surgery (AREA)
 - Heart & Thoracic Surgery (AREA)
 - Chemical Kinetics & Catalysis (AREA)
 - Biomedical Technology (AREA)
 - Molecular Biology (AREA)
 - Materials For Medical Uses (AREA)
 - Cardiology (AREA)
 - Polymers & Plastics (AREA)
 - Organic Chemistry (AREA)
 - Silicon Polymers (AREA)
 - Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
 
Abstract
Provided herein is a composite comprising: a polymer host selected from the group consisting of low density polyethylene (LDPE) linear low density polyethylene (LLDPE) polyethylene terephthalate (PET) polytetrafluoroethylene (PTFE) and polypropylene (PP) polyurethane polycaprolactone (PCL) polydimethylsiloxane (PDMS) polymethylmethacrylate (PMMA) and polyoxymethylene (POM); and a guest molecule comprising hyaluronic acid; wherein the guest molecule is disposed within the polymer host and wherein the guest molecule is covalently bonded to at least one other guest molecule. Also provided herein are methods for forming the composite and blood contracting devices made from the composite such as heart valves and vascular grafts.
  Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| US201261609818P | 2012-03-12 | 2012-03-12 | |
| PCT/US2013/030230 WO2013138240A1 (en) | 2012-03-12 | 2013-03-11 | Glycosaminoglycan and synthetic polymer materials for blood-contacting applications | 
Publications (1)
| Publication Number | Publication Date | 
|---|---|
| IN2014DN07588A true IN2014DN07588A (en) | 2015-04-24 | 
Family
ID=49161691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| IN7588DEN2014 IN2014DN07588A (en) | 2012-03-12 | 2013-03-11 | 
Country Status (8)
| Country | Link | 
|---|---|
| US (1) | US10071186B2 (en) | 
| EP (1) | EP2825203B1 (en) | 
| AU (1) | AU2013232382B2 (en) | 
| CA (1) | CA2866315C (en) | 
| ES (1) | ES2856830T3 (en) | 
| IN (1) | IN2014DN07588A (en) | 
| NZ (1) | NZ629494A (en) | 
| WO (1) | WO2013138240A1 (en) | 
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| DE102007043830A1 (en) | 2007-09-13 | 2009-04-02 | Lozonschi, Lucian, Madison | Heart valve stent | 
| EP3300695B1 (en) | 2009-12-08 | 2023-05-24 | Avalon Medical Ltd. | Device and system for transcatheter mitral valve replacement | 
| US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis | 
| US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis | 
| US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue | 
| EP4289398A3 (en) * | 2011-08-11 | 2024-03-13 | Tendyne Holdings, Inc. | Improvements for prosthetic valves and related inventions | 
| US9827092B2 (en) | 2011-12-16 | 2017-11-28 | Tendyne Holdings, Inc. | Tethers for prosthetic mitral valve | 
| US10266684B2 (en) * | 2012-03-12 | 2019-04-23 | Colorado State University Research Foundation | Glycosaminoglycan and synthetic polymer materials for blood-contacting applications | 
| US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system | 
| WO2014022124A1 (en) | 2012-07-28 | 2014-02-06 | Tendyne Holdings, Inc. | Improved multi-component designs for heart valve retrieval device, sealing structures and stent assembly | 
| WO2014021905A1 (en) | 2012-07-30 | 2014-02-06 | Tendyne Holdings, Inc. | Improved delivery systems and methods for transcatheter prosthetic valves | 
| US10463489B2 (en) | 2013-04-02 | 2019-11-05 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same | 
| US11224510B2 (en) | 2013-04-02 | 2022-01-18 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same | 
| US10478293B2 (en) | 2013-04-04 | 2019-11-19 | Tendyne Holdings, Inc. | Retrieval and repositioning system for prosthetic heart valve | 
| US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart | 
| US9610159B2 (en) | 2013-05-30 | 2017-04-04 | Tendyne Holdings, Inc. | Structural members for prosthetic mitral valves | 
| CN105658178B (en) | 2013-06-25 | 2018-05-08 | 坦迪尼控股股份有限公司 | Thrombus management and structural compliance features for prosthetic heart valves | 
| AU2014296087B2 (en) | 2013-08-01 | 2019-08-01 | Tendyne Holdings, Inc. | Epicardial anchor devices and methods | 
| WO2015058039A1 (en) | 2013-10-17 | 2015-04-23 | Robert Vidlund | Apparatus and methods for alignment and deployment of intracardiac devices | 
| EP3062744B1 (en) | 2013-10-28 | 2020-01-22 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems for delivering the same | 
| US9526611B2 (en) | 2013-10-29 | 2016-12-27 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of transcatheter prosthetic valves | 
| WO2015120122A2 (en) | 2014-02-05 | 2015-08-13 | Robert Vidlund | Apparatus and methods for transfemoral delivery of prosthetic mitral valve | 
| WO2015119721A1 (en) * | 2014-02-07 | 2015-08-13 | C. R. Bard, Inc. | Eptfe valves | 
| US9986993B2 (en) | 2014-02-11 | 2018-06-05 | Tendyne Holdings, Inc. | Adjustable tether and epicardial pad system for prosthetic heart valve | 
| JP6865037B2 (en) | 2014-03-10 | 2021-04-28 | テンダイン ホールディングス,インコーポレイテッド | Devices and methods for positioning the artificial mitral valve and monitoring the tether load of the artificial mitral valve | 
| AU2016205371B2 (en) | 2015-01-07 | 2019-10-10 | Tendyne Holdings, Inc. | Prosthetic mitral valves and apparatus and methods for delivery of same | 
| AU2016215197B2 (en) | 2015-02-05 | 2020-01-02 | Tendyne Holdings Inc. | Expandable epicardial pads and devices and methods for their delivery | 
| CA2983002C (en) | 2015-04-16 | 2023-07-04 | Tendyne Holdings, Inc. | Apparatus and methods for delivery, repositioning, and retrieval of transcatheter prosthetic valves | 
| US10327894B2 (en) | 2015-09-18 | 2019-06-25 | Tendyne Holdings, Inc. | Methods for delivery of prosthetic mitral valves | 
| CN105326581B (en) * | 2015-09-29 | 2017-12-26 | 中国科学院金属研究所 | A kind of method for preparing polyethylene glycol protein fiber composite heart valve prosthesis | 
| AU2016362474B2 (en) | 2015-12-03 | 2021-04-22 | Tendyne Holdings, Inc. | Frame features for prosthetic mitral valves | 
| CA3007660A1 (en) | 2015-12-15 | 2017-06-22 | Neovasc Tiara Inc. | Transseptal delivery system | 
| WO2017117109A1 (en) | 2015-12-28 | 2017-07-06 | Tendyne Holdings, Inc. | Atrial pocket closures for prosthetic heart valves | 
| US10433952B2 (en) | 2016-01-29 | 2019-10-08 | Neovasc Tiara Inc. | Prosthetic valve for avoiding obstruction of outflow | 
| US10470877B2 (en) | 2016-05-03 | 2019-11-12 | Tendyne Holdings, Inc. | Apparatus and methods for anterior valve leaflet management | 
| US11039921B2 (en) | 2016-06-13 | 2021-06-22 | Tendyne Holdings, Inc. | Sequential delivery of two-part prosthetic mitral valve | 
| JP6968113B2 (en) | 2016-06-30 | 2021-11-17 | テンダイン ホールディングス,インコーポレイテッド | Transapical delivery device for artificial heart valves | 
| WO2018013515A1 (en) | 2016-07-12 | 2018-01-18 | Tendyne Holdings, Inc. | Apparatus and methods for trans-septal retrieval of prosthetic heart valves | 
| BR102016021508A2 (en) * | 2016-09-19 | 2018-04-03 | Angel Maluf Miguel | METHOD FOR OBTAINING AN EXPANSIBLE HEART VALVE STENT FROM POLYURETHANE MEMBRANE AND STENT POLYURETHANE MEMBRANE VALVE FOR CATHETER IMPLANTS IN ADULT AND PEDIATRIC PATIENTS | 
| CA3042588A1 (en) | 2016-11-21 | 2018-05-24 | Neovasc Tiara Inc. | Methods and systems for rapid retraction of a transcatheter heart valve delivery system | 
| EP3630212A4 (en) * | 2017-05-30 | 2021-02-24 | Evonik Canada Inc. | Vascular prostheses with a modified surface | 
| PL3644904T3 (en) * | 2017-06-30 | 2025-06-30 | Ohio State Innovation Foundation | Prosthetic heart valve with tri-leaflet design for use in percutaneous valve replacement procedures | 
| US20220133474A1 (en) * | 2017-06-30 | 2022-05-05 | Ohio State Innovation Foundation | Methods to improve the durability of polymeric heart valves | 
| ES2975102T3 (en) | 2017-06-30 | 2024-07-03 | Ohio State Innovation Foundation | Three-leaflet cardiac valve prosthesis | 
| CN111050702B (en) | 2017-07-13 | 2022-07-05 | 坦迪尼控股股份有限公司 | Prosthetic heart valve and devices and methods for delivering the prosthetic heart valve | 
| CA3073834A1 (en) | 2017-08-25 | 2019-02-28 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis | 
| AU2018323900A1 (en) | 2017-08-28 | 2020-02-27 | Tendyne Holdings, Inc. | Prosthetic heart valves with tether coupling features | 
| WO2019195860A2 (en) | 2018-04-04 | 2019-10-10 | Vdyne, Llc | Devices and methods for anchoring transcatheter heart valve | 
| US10321995B1 (en) | 2018-09-20 | 2019-06-18 | Vdyne, Llc | Orthogonally delivered transcatheter heart valve replacement | 
| US11344413B2 (en) | 2018-09-20 | 2022-05-31 | Vdyne, Inc. | Transcatheter deliverable prosthetic heart valves and methods of delivery | 
| US11071627B2 (en) | 2018-10-18 | 2021-07-27 | Vdyne, Inc. | Orthogonally delivered transcatheter heart valve frame for valve in valve prosthesis | 
| US10595994B1 (en) | 2018-09-20 | 2020-03-24 | Vdyne, Llc | Side-delivered transcatheter heart valve replacement | 
| US12186187B2 (en) | 2018-09-20 | 2025-01-07 | Vdyne, Inc. | Transcatheter deliverable prosthetic heart valves and methods of delivery | 
| US11278437B2 (en) | 2018-12-08 | 2022-03-22 | Vdyne, Inc. | Compression capable annular frames for side delivery of transcatheter heart valve replacement | 
| US11109969B2 (en) | 2018-10-22 | 2021-09-07 | Vdyne, Inc. | Guidewire delivery of transcatheter heart valve | 
| CN113271890B (en) | 2018-11-08 | 2024-08-30 | 内奥瓦斯克迪亚拉公司 | Ventricular deployment of transcatheter mitral valve prosthesis | 
| US11253359B2 (en) | 2018-12-20 | 2022-02-22 | Vdyne, Inc. | Proximal tab for side-delivered transcatheter heart valves and methods of delivery | 
| WO2020146842A1 (en) | 2019-01-10 | 2020-07-16 | Vdyne, Llc | Anchor hook for side-delivery transcatheter heart valve prosthesis | 
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