IN2014DN06822A - - Google Patents

Info

Publication number
IN2014DN06822A
IN2014DN06822A IN6822DEN2014A IN2014DN06822A IN 2014DN06822 A IN2014DN06822 A IN 2014DN06822A IN 6822DEN2014 A IN6822DEN2014 A IN 6822DEN2014A IN 2014DN06822 A IN2014DN06822 A IN 2014DN06822A
Authority
IN
India
Prior art keywords
test solution
test
light source
magnets
detector
Prior art date
Application number
Inventor
Asuka Uchikawa
Shoichi Kanayama
Naru Ikeda
Original Assignee
Toshiba Kk
Toshiba Medical Sys Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toshiba Kk, Toshiba Medical Sys Corp filed Critical Toshiba Kk
Publication of IN2014DN06822A publication Critical patent/IN2014DN06822A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0439—Rotary sample carriers, i.e. carousels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0439—Rotary sample carriers, i.e. carousels
    • G01N2035/0446—Combinations of the above
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0439—Rotary sample carriers, i.e. carousels
    • G01N2035/0453—Multiple carousels working in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0439—Rotary sample carriers, i.e. carousels
    • G01N2035/0453—Multiple carousels working in parallel
    • G01N2035/0455—Coaxial carousels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The purpose of the present invention is to obtain highly accurate testing results in a sample testing device in which molecules to be detected are quantified by optically measuring the turbidity or absorbance of a test solution originating from magnetic particles. Magnets (41) apply a magnetic field to a test solution comprising a sample and magnetic particles accommodated in a test container (31). A photometric mechanism has a light source (210) and a detector (220). The light source (210) irradiates the test solution with light. The detector (220) is provided to a position opposing the light source (210) with the test container (31) interposed therebetween and detects light coming from the test solution. The magnets (41) have a geometric arrangement such that there is substantially uniform magnetic flux density of the magnetic field in the test solution inside the test container (31).
IN6822DEN2014 2012-08-31 2013-08-30 IN2014DN06822A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012192587 2012-08-31
PCT/JP2013/073448 WO2014034908A1 (en) 2012-08-31 2013-08-30 Sample testing device

Publications (1)

Publication Number Publication Date
IN2014DN06822A true IN2014DN06822A (en) 2015-05-22

Family

ID=50183710

Family Applications (1)

Application Number Title Priority Date Filing Date
IN6822DEN2014 IN2014DN06822A (en) 2012-08-31 2013-08-30

Country Status (5)

Country Link
US (1) US9470700B2 (en)
JP (2) JP6207933B2 (en)
CN (1) CN103765214B (en)
IN (1) IN2014DN06822A (en)
WO (1) WO2014034908A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3187832B1 (en) * 2014-08-26 2020-10-14 TDK Corporation Magnetic position detection device
WO2016043291A1 (en) * 2014-09-19 2016-03-24 協和メデックス株式会社 Method for cleaning magnetic carrier particles, device for cleaning magnetic carrier particles, and immunoassay method using magnetic carrier particles
CN104297039B (en) * 2014-09-25 2017-01-11 深圳市奥特库贝科技有限公司 Novel magnetic separation mechanism
EP3262397B1 (en) * 2015-02-27 2022-06-08 Hycor Biomedical, LLC Apparatuses for suspending and washing the contents of a plurality of cuvettes
JP6829950B2 (en) * 2016-05-31 2021-02-17 シスメックス株式会社 Analytical methods, analyzers and analytical systems
RU2762936C2 (en) * 2016-10-28 2021-12-24 Бекман Каултер, Инк. System for assessing substance preparation
US11041756B2 (en) 2017-10-20 2021-06-22 Charted Scientific Inc. Method and apparatus of filtering light using a spectrometer enhanced with additional spectral filters with optical analysis of fluorescence and scattered light from particles suspended in a liquid medium using confocal and non confocal illumination and imaging
US10585028B2 (en) 2017-10-20 2020-03-10 Charted Scientific, Inc. Method and apparatus for optical analysis
JP7076282B2 (en) * 2018-05-11 2022-05-27 株式会社日立ハイテク Stirrer, analyzer, dispensing method
CN110832301B (en) * 2018-05-30 2022-05-27 务实诊断有限公司 Optical magneto-optical method for detecting biological and chemical substances
CN111239079B (en) * 2020-03-09 2022-11-11 上海交通大学 A time-varying turbidity field simulation device with a fixed optical depth
JP7507899B2 (en) * 2021-01-26 2024-06-28 京セラ株式会社 Liquid storage container and method of manufacturing same
CN113030068A (en) * 2021-02-01 2021-06-25 苏州易莱生物技术有限公司 Electrochemiluminescence detection device
KR102455161B1 (en) * 2021-04-23 2022-10-18 대전대학교 산학협력단 Apparatus for spectroscopy using electric and magnetic fields and led
CN114136927A (en) * 2021-10-15 2022-03-04 国科温州研究院(温州生物材料与工程研究所) A kind of solution magnetic detection device and detection method thereof

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62118255A (en) * 1985-11-19 1987-05-29 Toshimitsu Musha Detection of immunological reaction by using magnetic field
JPS62168636A (en) * 1986-01-20 1987-07-24 Kao Corp Coating agent for mold mandrel
JP2510551B2 (en) 1987-01-30 1996-06-26 三菱化学株式会社 Method for measuring antigen-antibody reaction
JPS63210773A (en) * 1987-02-27 1988-09-01 Toshimitsu Musha Method for accelerating specific bond reaction
JP2603843B2 (en) 1988-01-29 1997-04-23 三菱化学株式会社 Measuring method of antigen or antibody
US5200084A (en) * 1990-09-26 1993-04-06 Immunicon Corporation Apparatus and methods for magnetic separation
JP2967597B2 (en) * 1991-03-07 1999-10-25 富士通株式会社 Potentiometer
US5186827A (en) * 1991-03-25 1993-02-16 Immunicon Corporation Apparatus for magnetic separation featuring external magnetic means
JPH0572206A (en) * 1991-06-28 1993-03-23 Olympus Optical Co Ltd Detecting method of agglutination reaction using magnetic field
JPH05144628A (en) * 1991-11-18 1993-06-11 Shin Etsu Chem Co Ltd Magnetic field generator
JPH0663150U (en) * 1993-02-15 1994-09-06 東レ株式会社 Unreacted component removal device
JP3249609B2 (en) * 1992-11-25 2002-01-21 三菱化学株式会社 Immunochemical measurement device
JPH06213900A (en) 1993-01-21 1994-08-05 Hitachi Ltd Method device for settlement fractional measurement using magnetic particle
DE59410037D1 (en) 1993-09-17 2002-03-14 Hoffmann La Roche Analysis device with a device for separating magnetic microparticles
JP3355246B2 (en) * 1994-05-25 2002-12-09 三菱化学株式会社 Immunochemical measurement device
JPH08178931A (en) * 1994-12-22 1996-07-12 Toshiba Corp Automatic analyzer
JP3213798B2 (en) * 1996-06-04 2001-10-02 株式会社日立製作所 Chemical analyzer
DE69729101T2 (en) * 1996-06-07 2005-05-12 Immunivest Corp., Wilmington MAGNETIC SEPARATION WITH THE HELP OF EXTERNAL AND INTERNAL GRADIENTS
JP4043132B2 (en) * 1998-03-19 2008-02-06 オリンパス株式会社 Automatic analyzer
JP2000346843A (en) * 1999-06-02 2000-12-15 Tdk Corp Immunological many-item measuring method
CA2949524C (en) * 2003-07-18 2017-07-04 Bio-Rad Laboratories, Inc. System and method for multi-analyte detection
JP2006078182A (en) * 2004-09-07 2006-03-23 Jeol Ltd Static magnetic field generator for magnetic resonance equipment
JP4902205B2 (en) * 2006-01-23 2012-03-21 シスメックス株式会社 Analysis apparatus and analysis method
JP5276980B2 (en) * 2006-06-30 2013-08-28 Ｊｎｃ株式会社 Detection target, quantitative kit, and detection, quantitative method
DE102007043281A1 (en) * 2007-09-11 2009-05-28 Sebastian Dr. med. Chakrit Bhakdi Apparatus, materials and methods for high gradient magnetic separation of biological material
JP5214982B2 (en) * 2008-01-16 2013-06-19 オーソ・クリニカル・ダイアグノスティックス株式会社 Inspection device
CN101319976B (en) * 2008-07-03 2010-08-25 清华大学 Micro-pore plate type electromagnetic separator
EP2177271B8 (en) * 2008-10-15 2019-12-18 F. Hoffmann-La Roche AG Magnetic separation system comprising flexible magnetic pins and corresponding method

Also Published As

Publication number Publication date
WO2014034908A1 (en) 2014-03-06
JP2014062901A (en) 2014-04-10
US9470700B2 (en) 2016-10-18
JP6491287B2 (en) 2019-03-27
CN103765214A (en) 2014-04-30
JP6207933B2 (en) 2017-10-04
US20140356235A1 (en) 2014-12-04
CN103765214B (en) 2015-10-21
JP2017227650A (en) 2017-12-28

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