IN2014CN03683A - - Google Patents

Download PDF

Info

Publication number
IN2014CN03683A
IN2014CN03683A IN3683CHN2014A IN2014CN03683A IN 2014CN03683 A IN2014CN03683 A IN 2014CN03683A IN 3683CHN2014 A IN3683CHN2014 A IN 3683CHN2014A IN 2014CN03683 A IN2014CN03683 A IN 2014CN03683A
Authority
IN
India
Prior art keywords
biological valve
artificial biological
pretreated
glutaraldehyde
groups
Prior art date
Application number
Inventor
Dakai Chen
Yu Li
Cong Tian
Yuan Fang
Jiaoming Dong
Cheng Chen
Xiulan Cheng
Guoming Chen
Chengjun Le
Qiyi Luo
Original Assignee
Shanghai Microport Medical Group Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Microport Medical Group Co Ltd filed Critical Shanghai Microport Medical Group Co Ltd
Publication of IN2014CN03683A publication Critical patent/IN2014CN03683A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2415—Manufacturing methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3625—Vascular tissue, e.g. heart valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0029—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in bending or flexure capacity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/02—Treatment of implants to prevent calcification or mineralisation in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/20—Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A method for preparing an edge rigidized artificial biological valve comprising: first soaking an artificial biological valve in a pretreated glutaraldehyde solution wherein the artificial biological valve can be partly fixed with glutaraldehyde before after or during contact with the pretreated glutaraldehyde solution; and then closing the free aldehyde groups carboxyl groups amino groups hydroxyl groups and carbonyl groups formed by the artificial biological valve pretreated with glutaraldehyde with a reducing agent and tannin extract. The edge rigidity of the artificial biological valve is enhanced so that the long term stability and durability of the artificial biological valve are improved.
IN3683CHN2014 2011-11-01 2011-12-14 IN2014CN03683A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201110339534.3A CN102499993B (en) 2011-11-01 2011-11-01 Method for preparing edge rigidized artificial biological valve
PCT/CN2011/083987 WO2013063842A1 (en) 2011-11-01 2011-12-14 Method for preparing edge-rigidized artificial biological valve

Publications (1)

Publication Number Publication Date
IN2014CN03683A true IN2014CN03683A (en) 2015-09-04

Family

ID=46212166

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3683CHN2014 IN2014CN03683A (en) 2011-11-01 2011-12-14

Country Status (7)

Country Link
EP (1) EP2774630B1 (en)
CN (1) CN102499993B (en)
AU (1) AU2011380375B2 (en)
BR (1) BR112014010668B1 (en)
ES (1) ES2639424T3 (en)
IN (1) IN2014CN03683A (en)
WO (1) WO2013063842A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
US10433952B2 (en) 2016-01-29 2019-10-08 Neovasc Tiara Inc. Prosthetic valve for avoiding obstruction of outflow
EP3541462A4 (en) 2016-11-21 2020-06-17 Neovasc Tiara Inc. Methods and systems for rapid retraction of a transcatheter heart valve delivery system
CN107007887B (en) * 2017-02-27 2020-10-02 杭州启明医疗器械股份有限公司 Cross-linked artificial biological valve and preparation method thereof
US10856984B2 (en) 2017-08-25 2020-12-08 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
WO2019092736A1 (en) * 2017-11-13 2019-05-16 Meril Life Sciences Pvt Ltd Anti-calcification of a tissue
EP3934591A4 (en) 2019-03-08 2022-11-23 Neovasc Tiara Inc. Retrievable prosthesis delivery system
JP7438236B2 (en) 2019-04-01 2024-02-26 ニオバスク ティアラ インコーポレイテッド Controllably deployable prosthetic valve
CA3136334A1 (en) 2019-04-10 2020-10-15 Neovasc Tiara Inc. Prosthetic valve with natural blood flow
CN114025813B (en) 2019-05-20 2024-05-14 内奥瓦斯克迪亚拉公司 Introducer with hemostatic mechanism
CN114144144A (en) 2019-06-20 2022-03-04 内奥瓦斯克迪亚拉公司 Low-profile prosthetic mitral valve
WO2021118964A1 (en) * 2019-12-09 2021-06-17 Edwards Lifesciences Corporation Bioprosthetic tissue preparation
CN111467574B (en) * 2020-04-21 2021-01-26 四川大学 Biological valve material based on EDC/NHS activation and recombinant human collagen modification and preparation method thereof
CN115998955A (en) * 2022-12-09 2023-04-25 首都医科大学附属北京安贞医院 Aldehyde-chromium composite crosslinking method of venous bridge
CN117563049B (en) * 2024-01-15 2024-05-03 北京佰仁医疗科技股份有限公司 Ophthalmic biological patch for posterior scleral reinforcement and preparation thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2523810B1 (en) * 1982-03-23 1988-11-25 Carpentier Alain ORGANIC GRAFT FABRIC AND PROCESS FOR ITS PREPARATION
EP0804255B1 (en) * 1994-07-29 2001-10-04 Edwards Lifesciences Corporation Methods for treating implantable biological tissues to mitigate the calcification thereof
EP0888142B1 (en) * 1996-03-04 2003-05-28 Edwards Lifesciences Corporation Nonpolymeric epoxy compounds for cross-linking biological tissue and bioprosthetic grafts prepared thereby
AU3229697A (en) * 1996-06-03 1998-01-05 Gore Enterprise Holdings, Inc. Improved blood contact surfaces using extracellular matrix synthesized (in vitro) having bioactive species immobilized thereto
US6214054B1 (en) * 1998-09-21 2001-04-10 Edwards Lifesciences Corporation Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby
JP2003509168A (en) * 1999-09-22 2003-03-11 バクスター・インターナショナル・インコーポレイテッド Heart valve and biological tissue preparation method
US20040153145A1 (en) * 2002-11-26 2004-08-05 Clemson University Fixation method for bioprostheses
US7579381B2 (en) * 2005-03-25 2009-08-25 Edwards Lifesciences Corporation Treatment of bioprosthetic tissues to mitigate post implantation calcification
US20060217804A1 (en) * 2005-03-25 2006-09-28 Dove Jeffrey S Treatment of bioprosthetic tissues to mitigate post implantation calcification
CN101161293A (en) * 2006-10-12 2008-04-16 胡盛寿 Resist calcification modified method of heterogeneity biological organization material
CN102114269B (en) * 2011-02-22 2013-12-11 上海微创医疗器械（集团）有限公司 Isocyano group-blocking anti-calcification artificial biological valve and preparation method thereof

Also Published As

Publication number Publication date
BR112014010668B1 (en) 2019-04-02
EP2774630A1 (en) 2014-09-10
CN102499993A (en) 2012-06-20
EP2774630A4 (en) 2015-07-22
EP2774630B1 (en) 2017-07-05
AU2011380375B2 (en) 2015-09-17
CN102499993B (en) 2014-01-15
WO2013063842A1 (en) 2013-05-10
AU2011380375A1 (en) 2014-05-29
ES2639424T3 (en) 2017-10-26
BR112014010668A2 (en) 2017-12-05

Similar Documents

Publication Publication Date Title
IN2014CN03683A (en)
MX349658B (en) Method for differentiation of pluripotent stem cells into vascular bed cells.
GB2485725A (en) Systems and methods for optimizing enterprise performance
WO2011022369A3 (en) Method for processing tissues
MX342200B (en) Method for processing mesenchymal stem cells and the use thereof in the treatment of diseases associated with oxidative stress.
AR060902A1 (en) DRINK PRESERVERS
MX2013011430A (en) Protein beverage and method of making the same.
MY178152A (en) Isolation of stem cells from adipose tissue by ultrasonic cavitation, and methods of use
EA201300780A1 (en) METHOD FOR OBTAINING INDUCED PLURIPOTENT STEM CELLS AND DIFFERENTIATED CELLS
WO2010088064A3 (en) Preservation of ergothioneine
WO2013028262A3 (en) Systems and methods for stimulating cellular function in tissue
RU2013134126A (en) METHOD FOR REDUCING THE LEVEL OF THE C-END BODY COLLAGEN TYPE 2
AR077403A1 (en) A METHOD FOR THE PRODUCTION OF AN ALCOHOLIC DRINK WITH A REDUCED ALCOHOL CONTENT
MX2013000026A (en) Stabilizing and dyeing process for strawberries.
MX2016006656A (en) Methods of treating antibody-mediated rejection in organ transplant patients with c1-esterase inhibitor.
GB2497453A (en) Pharmaceutical composition and methods of treating and preventing the diseases caused by HIV or associated with HIV
MX2013007053A (en) Use of a nitrogen- free peroxygen- releasing compound to reduce growth of contaminant microorganisms in ethanol fermentation.
MX346515B (en) Effervescent compositions and uses thereof.
MX2014006192A (en) Methods for the preparation of hydrogels using lipase enzymes.
WO2012116055A3 (en) Methods for improving the appearance of hyperpigmented skin using a synergistic composition comprising banyan tree, lotus, and clover serum fractions
ATE521249T1 (en) METHOD FOR PRODUCING FERMENTED BEVERAGES
MX2014013049A (en) Compositions and methods for heparan sulfate as a biomarker for transplant rejection.
WO2011129607A8 (en) Method for increasing stem cell activity and stem cells produced thereby
EP2683392A4 (en) Cinnamomum burmanii extract, extraction process and its use as proton pump down-regulator, enzyme inhibitor, and mucoprotector
UA110996C2 (en) Method for acetate producing