IN2014CN02963A - - Google Patents
Info
- Publication number
- IN2014CN02963A IN2014CN02963A IN2963CHN2014A IN2014CN02963A IN 2014CN02963 A IN2014CN02963 A IN 2014CN02963A IN 2963CHN2014 A IN2963CHN2014 A IN 2963CHN2014A IN 2014CN02963 A IN2014CN02963 A IN 2014CN02963A
- Authority
- IN
- India
- Prior art keywords
- strains
- generating
- methods
- host cells
- relates
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161552674P | 2011-10-28 | 2011-10-28 | |
| PCT/US2012/061432 WO2013062940A1 (en) | 2011-10-28 | 2012-10-23 | Engineered lower eukaryotic host strains for recombinant protein expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN02963A true IN2014CN02963A (pm) | 2015-07-03 |
Family
ID=48168381
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2963CHN2014 IN2014CN02963A (pm) | 2011-10-28 | 2012-10-23 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9328367B2 (pm) |
| EP (1) | EP2771461B1 (pm) |
| JP (1) | JP2014532406A (pm) |
| KR (1) | KR20140091018A (pm) |
| CN (1) | CN104024409A (pm) |
| AU (1) | AU2012329091A1 (pm) |
| CA (1) | CA2853341A1 (pm) |
| IN (1) | IN2014CN02963A (pm) |
| WO (1) | WO2013062940A1 (pm) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2772613C (en) | 2009-09-03 | 2020-03-10 | Schering Corporation | Anti-gitr antibodies |
| KR20140091018A (ko) | 2011-10-28 | 2014-07-18 | 머크 샤프 앤드 돔 코포레이션 | 재조합 단백질 발현을 위한 조작된 하등 진핵 숙주 균주 |
| KR20140134272A (ko) * | 2012-02-16 | 2014-11-21 | 머크 샤프 앤드 돔 코포레이션 | 효모에서 만노실트랜스퍼라제 활성을 감소시키는 방법 |
| EP2909306B1 (en) | 2012-10-22 | 2019-12-11 | Merck Sharp & Dohme Corp. | Crz1 mutant fungal cells |
| KR20170118104A (ko) * | 2015-03-03 | 2017-10-24 | 산도즈 아게 | 구성적 효모 llp 프로모터-기반 발현 시스템 |
| EP3455635A1 (en) * | 2016-05-13 | 2019-03-20 | The University of Copenhagen | A cell-based array platform |
| JP2018038286A (ja) * | 2016-09-05 | 2018-03-15 | 国立大学法人神戸大学 | 新規宿主細胞及びそれを用いた目的タンパク質の製造方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002541863A (ja) * | 1999-04-21 | 2002-12-10 | ワイス | Ｎ−型イオンチャンネル不活性化のモジュレーターを同定する方法 |
| US20060148000A1 (en) * | 1999-04-21 | 2006-07-06 | Wyeth | Methods for identifying modulators of N-type ion channel inactivation |
| BR0110214A (pt) * | 2000-04-24 | 2003-01-21 | Wyeth Corp | Célula de levedura e métodos de detecção da interação de um primeiro peptìdio com um segundo peptìdio de um par de ligação de peptìdios, de determinação da interação de uma amostra de teste com um primeiro ou um segundo peptìdios de um par de ligação de peptìdios e de detecção simultânea da interação de dois pares de ligação de peptìdios diferentes |
| DK1283265T3 (da) | 2000-05-17 | 2009-11-09 | Mitsubishi Tanabe Pharma Corp | Fremgangsmåde til fremstilling af protein med reduktion af mannosephosphat i sukkerkæden og glycoprotein fremstillet derved |
| JP2004501642A (ja) | 2000-06-28 | 2004-01-22 | グライコフィ， インコーポレイテッド | 改変された糖タンパク質を生成するための方法 |
| US7795002B2 (en) | 2000-06-28 | 2010-09-14 | Glycofi, Inc. | Production of galactosylated glycoproteins in lower eukaryotes |
| JP4861830B2 (ja) | 2003-12-24 | 2012-01-25 | グライコフィ， インコーポレイテッド | 糖タンパク質の産生において、グリカンのマンノシルリン酸化を除去する方法 |
| CA2565125A1 (en) * | 2004-04-29 | 2005-11-10 | Glycofi, Inc. | Methods for reducing or eliminating alpha-mannosidase resistant glycans in the production of glycoproteins |
| CN101606769A (zh) | 2009-07-15 | 2009-12-23 | 陈德芳 | 一种宝石连接结构 |
| AR087433A1 (es) * | 2011-08-08 | 2014-03-26 | Merck Sharp & Dohme | Analogos de insulina n-glicosilados |
| KR20140091018A (ko) | 2011-10-28 | 2014-07-18 | 머크 샤프 앤드 돔 코포레이션 | 재조합 단백질 발현을 위한 조작된 하등 진핵 숙주 균주 |
-
2012
- 2012-10-23 KR KR1020147013881A patent/KR20140091018A/ko not_active Withdrawn
- 2012-10-23 EP EP12843508.8A patent/EP2771461B1/en active Active
- 2012-10-23 US US14/354,628 patent/US9328367B2/en active Active
- 2012-10-23 CN CN201280064747.2A patent/CN104024409A/zh active Pending
- 2012-10-23 JP JP2014538873A patent/JP2014532406A/ja active Pending
- 2012-10-23 IN IN2963CHN2014 patent/IN2014CN02963A/en unknown
- 2012-10-23 CA CA2853341A patent/CA2853341A1/en not_active Abandoned
- 2012-10-23 AU AU2012329091A patent/AU2012329091A1/en not_active Abandoned
- 2012-10-23 WO PCT/US2012/061432 patent/WO2013062940A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014532406A (ja) | 2014-12-08 |
| EP2771461A1 (en) | 2014-09-03 |
| KR20140091018A (ko) | 2014-07-18 |
| CA2853341A1 (en) | 2013-05-02 |
| US9328367B2 (en) | 2016-05-03 |
| WO2013062940A1 (en) | 2013-05-02 |
| EP2771461B1 (en) | 2019-12-04 |
| CN104024409A (zh) | 2014-09-03 |
| AU2012329091A1 (en) | 2014-05-01 |
| US20140302557A1 (en) | 2014-10-09 |
| EP2771461A4 (en) | 2015-06-17 |
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