IN2014CN02963A - - Google Patents
Info
- Publication number
- IN2014CN02963A IN2014CN02963A IN2963CHN2014A IN2014CN02963A IN 2014CN02963 A IN2014CN02963 A IN 2014CN02963A IN 2963CHN2014 A IN2963CHN2014 A IN 2963CHN2014A IN 2014CN02963 A IN2014CN02963 A IN 2014CN02963A
- Authority
- IN
- India
- Prior art keywords
- strains
- generating
- methods
- host cells
- relates
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161552674P | 2011-10-28 | 2011-10-28 | |
| PCT/US2012/061432 WO2013062940A1 (en) | 2011-10-28 | 2012-10-23 | Engineered lower eukaryotic host strains for recombinant protein expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN02963A true IN2014CN02963A (forum.php) | 2015-07-03 |
Family
ID=48168381
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2963CHN2014 IN2014CN02963A (forum.php) | 2011-10-28 | 2012-10-23 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9328367B2 (forum.php) |
| EP (1) | EP2771461B1 (forum.php) |
| JP (1) | JP2014532406A (forum.php) |
| KR (1) | KR20140091018A (forum.php) |
| CN (1) | CN104024409A (forum.php) |
| AU (1) | AU2012329091A1 (forum.php) |
| CA (1) | CA2853341A1 (forum.php) |
| IN (1) | IN2014CN02963A (forum.php) |
| WO (1) | WO2013062940A1 (forum.php) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101790802B1 (ko) | 2009-09-03 | 2017-10-27 | 머크 샤프 앤드 돔 코포레이션 | 항-ｇｉｔｒ 항체 |
| EP2771461B1 (en) | 2011-10-28 | 2019-12-04 | Merck Sharp & Dohme Corp. | Engineered lower eukaryotic host strains for recombinant protein expression |
| US9416389B2 (en) * | 2012-02-16 | 2016-08-16 | Merck Sharp & Dohme Corp. | Methods for reducing mannosyltransferase activity in lower eukaryotes |
| WO2014066134A1 (en) * | 2012-10-22 | 2014-05-01 | Merck Sharp & Dohme Corp. | Crz1 mutant fungal cells |
| EP3889169A1 (en) * | 2015-03-03 | 2021-10-06 | Novartis AG | Constitutive yeast llp promoter-based expression system |
| WO2017194699A1 (en) * | 2016-05-13 | 2017-11-16 | University Of Copenhagen | A cell-based array platform |
| JP2018038286A (ja) * | 2016-09-05 | 2018-03-15 | 国立大学法人神戸大学 | 新規宿主細胞及びそれを用いた目的タンパク質の製造方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060148000A1 (en) * | 1999-04-21 | 2006-07-06 | Wyeth | Methods for identifying modulators of N-type ion channel inactivation |
| EP1194756A4 (en) * | 1999-04-21 | 2004-12-29 | Wyeth Corp | METHODS OF IDENTIFYING N-TYPE ION CHANNEL INACTIVATION MODULATORS |
| WO2001081548A1 (en) * | 2000-04-24 | 2001-11-01 | Wyeth | Novel cell systems having specific interaction of peptide binding pairs |
| JP4969011B2 (ja) | 2000-05-17 | 2012-07-04 | 田辺三菱製薬株式会社 | 酸性糖鎖減少蛋白質の製造方法および該製造された糖蛋白質 |
| EP1522590B1 (en) | 2000-06-28 | 2009-08-26 | Glycofi, Inc. | Methods for producing modified glycoproteins |
| US7795002B2 (en) | 2000-06-28 | 2010-09-14 | Glycofi, Inc. | Production of galactosylated glycoproteins in lower eukaryotes |
| JP4861830B2 (ja) | 2003-12-24 | 2012-01-25 | グライコフィ， インコーポレイテッド | 糖タンパク質の産生において、グリカンのマンノシルリン酸化を除去する方法 |
| US7465577B2 (en) | 2004-04-29 | 2008-12-16 | Glycofi, Inc. | Methods for reducing or eliminating α-mannosidase resistant glycans for the production of glycoproteins |
| CN101606769A (zh) | 2009-07-15 | 2009-12-23 | 陈德芳 | 一种宝石连接结构 |
| AR087433A1 (es) * | 2011-08-08 | 2014-03-26 | Merck Sharp & Dohme | Analogos de insulina n-glicosilados |
| EP2771461B1 (en) | 2011-10-28 | 2019-12-04 | Merck Sharp & Dohme Corp. | Engineered lower eukaryotic host strains for recombinant protein expression |
-
2012
- 2012-10-23 EP EP12843508.8A patent/EP2771461B1/en active Active
- 2012-10-23 JP JP2014538873A patent/JP2014532406A/ja active Pending
- 2012-10-23 US US14/354,628 patent/US9328367B2/en active Active
- 2012-10-23 CN CN201280064747.2A patent/CN104024409A/zh active Pending
- 2012-10-23 CA CA2853341A patent/CA2853341A1/en not_active Abandoned
- 2012-10-23 AU AU2012329091A patent/AU2012329091A1/en not_active Abandoned
- 2012-10-23 KR KR1020147013881A patent/KR20140091018A/ko not_active Withdrawn
- 2012-10-23 IN IN2963CHN2014 patent/IN2014CN02963A/en unknown
- 2012-10-23 WO PCT/US2012/061432 patent/WO2013062940A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| KR20140091018A (ko) | 2014-07-18 |
| EP2771461A1 (en) | 2014-09-03 |
| US20140302557A1 (en) | 2014-10-09 |
| EP2771461A4 (en) | 2015-06-17 |
| US9328367B2 (en) | 2016-05-03 |
| WO2013062940A1 (en) | 2013-05-02 |
| AU2012329091A1 (en) | 2014-05-01 |
| CN104024409A (zh) | 2014-09-03 |
| CA2853341A1 (en) | 2013-05-02 |
| JP2014532406A (ja) | 2014-12-08 |
| EP2771461B1 (en) | 2019-12-04 |
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