IN2014CN02398A - - Google Patents
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- Publication number
- IN2014CN02398A IN2014CN02398A IN2398CHN2014A IN2014CN02398A IN 2014CN02398 A IN2014CN02398 A IN 2014CN02398A IN 2398CHN2014 A IN2398CHN2014 A IN 2398CHN2014A IN 2014CN02398 A IN2014CN02398 A IN 2014CN02398A
- Authority
- IN
- India
- Prior art keywords
- peptidomimetics
- salts
- making
- methods
- hydrogen bond
- Prior art date
Links
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 150000003973 alkyl amines Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000816 peptidomimetic Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000003568 thioethers Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161529414P | 2011-08-31 | 2011-08-31 | |
| PCT/US2012/053538 WO2013033645A1 (en) | 2011-08-31 | 2012-08-31 | Thioether-,ether-, and alkylamine-linked hydrogen bond surrogate pertidomimentics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN02398A true IN2014CN02398A (OSRAM) | 2015-06-19 |
Family
ID=47756932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2398CHN2014 IN2014CN02398A (OSRAM) | 2011-08-31 | 2012-08-31 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20130123196A1 (OSRAM) |
| EP (1) | EP3041491A1 (OSRAM) |
| CN (1) | CN103889437A (OSRAM) |
| AU (1) | AU2012301605A1 (OSRAM) |
| IN (1) | IN2014CN02398A (OSRAM) |
| WO (1) | WO2013033645A1 (OSRAM) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105061577A (zh) | 2006-12-14 | 2015-11-18 | 爱勒让治疗公司 | 双巯基大环化系统 |
| PT2118123E (pt) | 2007-01-31 | 2016-02-10 | Harvard College | Péptidos de p53 estabilizados e suas utilizações |
| CN109627287A (zh) | 2007-02-23 | 2019-04-16 | 爱勒让治疗公司 | 三唑大环系统 |
| JP5631201B2 (ja) | 2007-03-28 | 2014-11-26 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ステッチングされたポリペプチド |
| BRPI0918948A2 (pt) | 2008-09-22 | 2015-12-15 | Aileron Therapeutics Inc | macrociclos peptidomiméticos |
| JP2012509902A (ja) | 2008-11-24 | 2012-04-26 | エルロン・セラピューティクス・インコーポレイテッド | 改善された特性を有するペプチド模倣大環状分子 |
| EP2376100B1 (en) | 2009-01-14 | 2017-10-25 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| WO2011038049A1 (en) | 2009-09-22 | 2011-03-31 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| MX355543B (es) | 2010-08-13 | 2018-04-20 | Aileron Therapeutics Inc Star | Macrociclos peptidomiméticos. |
| TWI643868B (zh) | 2011-10-18 | 2018-12-11 | 艾利倫治療公司 | 擬肽巨環化合物 |
| WO2013096755A1 (en) | 2011-12-21 | 2013-06-27 | New York University | Proteolytically resistant hydrogen bond surrogate helices |
| SG11201404648PA (en) | 2012-02-15 | 2014-09-26 | Aileron Therapeutics Inc | Peptidomimetic macrocycles |
| EP2819688A4 (en) | 2012-02-15 | 2015-10-28 | Aileron Therapeutics Inc | PEPTIDOMIMETIC MACROCYCLES CROSS-LINKED WITH TRIAZOLE AND THIOETHER |
| KR20150082307A (ko) | 2012-11-01 | 2015-07-15 | 에일러론 테라퓨틱스 인코포레이티드 | 이치환 아미노산 및 이의 제조 및 사용 방법 |
| EP2964245A4 (en) * | 2013-01-19 | 2016-09-21 | Univ New York | HYDROGENIC SURROGATE PEPTIDES AND PEPTIDOMIMETICS FOR THE REACTIVATION OF P53 |
| US20150065436A1 (en) * | 2013-09-03 | 2015-03-05 | University Of Southern California | INHIBITING INTERACTION BETWEEN HIF-1ALPHA AND p300/CBP WITH HYDROGEN BOND SURROGATE-BASED HELICES |
| SG11201702223UA (en) | 2014-09-24 | 2017-04-27 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and uses thereof |
| EP3197477A4 (en) | 2014-09-24 | 2018-07-04 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and formulations thereof |
| KR20170129879A (ko) | 2015-03-20 | 2017-11-27 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티드모방 거대고리 및 이의 용도 |
| US10059741B2 (en) | 2015-07-01 | 2018-08-28 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| JP2018528217A (ja) | 2015-09-10 | 2018-09-27 | エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | Ｍｃｌ−１のモジュレーターとしてのペプチド模倣大環状分子 |
| CR20180232A (es) | 2015-10-27 | 2018-05-31 | Hoffmann La Roche | Macrociclos peptídicos contra acinetobacter baumannii |
| EP3388444A1 (en) | 2017-04-10 | 2018-10-17 | F. Hoffmann-La Roche AG | Anti-bacterial peptide macrocycles and use thereof |
| US11505573B2 (en) | 2018-03-28 | 2022-11-22 | Hoffmann-La Roche Inc. | Peptide macrocycles against Acinetobacter baumannii |
| US11819532B2 (en) | 2018-04-23 | 2023-11-21 | Hoffmann-La Roche Inc. | Peptide macrocycles against Acinetobacter baumannii |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1483290E (pt) * | 2002-01-17 | 2008-09-19 | Takeda Pharmaceutical | Peptídeos e peptidomiméticos possuindo actividade antiproliferativa e/ou que aumentam os agentes ou tratamentos de danificação dos ácidos nucleicos |
| AU2002342618C1 (en) * | 2002-08-20 | 2008-10-30 | Polyphor Ltd. | Template-fixed peptidomimetics with antibacterial activity |
| WO2005118620A2 (en) * | 2004-05-27 | 2005-12-15 | New York University | Methods for preparing internally constraied peptides and peptidomimetics |
| BRPI0918948A2 (pt) * | 2008-09-22 | 2015-12-15 | Aileron Therapeutics Inc | macrociclos peptidomiméticos |
| JP2012509902A (ja) * | 2008-11-24 | 2012-04-26 | エルロン・セラピューティクス・インコーポレイテッド | 改善された特性を有するペプチド模倣大環状分子 |
| WO2013096755A1 (en) * | 2011-12-21 | 2013-06-27 | New York University | Proteolytically resistant hydrogen bond surrogate helices |
| WO2013126703A1 (en) * | 2012-02-22 | 2013-08-29 | New York University | Reversibly crosslinked helical hydrogen bond surrogate macrocycles |
| US20150065436A1 (en) * | 2013-09-03 | 2015-03-05 | University Of Southern California | INHIBITING INTERACTION BETWEEN HIF-1ALPHA AND p300/CBP WITH HYDROGEN BOND SURROGATE-BASED HELICES |
-
2012
- 2012-08-31 IN IN2398CHN2014 patent/IN2014CN02398A/en unknown
- 2012-08-31 US US13/601,648 patent/US20130123196A1/en not_active Abandoned
- 2012-08-31 WO PCT/US2012/053538 patent/WO2013033645A1/en not_active Ceased
- 2012-08-31 AU AU2012301605A patent/AU2012301605A1/en not_active Abandoned
- 2012-08-31 CN CN201280051966.7A patent/CN103889437A/zh active Pending
- 2012-08-31 EP EP12827266.3A patent/EP3041491A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP3041491A1 (en) | 2016-07-13 |
| AU2012301605A1 (en) | 2014-04-17 |
| CN103889437A (zh) | 2014-06-25 |
| WO2013033645A1 (en) | 2013-03-07 |
| US20130123196A1 (en) | 2013-05-16 |
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