IN2014CN00348A - - Google Patents

Info

Publication number
IN2014CN00348A
IN2014CN00348A IN348CHN2014A IN2014CN00348A IN 2014CN00348 A IN2014CN00348 A IN 2014CN00348A IN 348CHN2014 A IN348CHN2014 A IN 348CHN2014A IN 2014CN00348 A IN2014CN00348 A IN 2014CN00348A
Authority
IN
India
Prior art keywords
agomelatine
preparation
crystalline form
invention concerns
freeze drying
Prior art date
Application number
Other languages
English (en)
Inventor
Giorgio Bertolini
Angelis Bruno De
Original Assignee
Laboratorio Chimico Int Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Chimico Int Spa filed Critical Laboratorio Chimico Int Spa
Publication of IN2014CN00348A publication Critical patent/IN2014CN00348A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/25Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/22Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Battery Electrode And Active Subsutance (AREA)
IN348CHN2014 2011-08-03 2011-08-03 IN2014CN00348A (enrdf_load_stackoverflow)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2011/001805 WO2013017903A1 (en) 2011-08-03 2011-08-03 Process for the preparation of crystalline form i of agomelatine

Publications (1)

Publication Number Publication Date
IN2014CN00348A true IN2014CN00348A (enrdf_load_stackoverflow) 2015-04-03

Family

ID=44802320

Family Applications (1)

Application Number Title Priority Date Filing Date
IN348CHN2014 IN2014CN00348A (enrdf_load_stackoverflow) 2011-08-03 2011-08-03

Country Status (16)

Country Link
US (1) US20150291508A1 (enrdf_load_stackoverflow)
EP (1) EP2739605B1 (enrdf_load_stackoverflow)
CN (1) CN103827078B (enrdf_load_stackoverflow)
BR (1) BR112014002523A2 (enrdf_load_stackoverflow)
CA (1) CA2843827A1 (enrdf_load_stackoverflow)
CY (1) CY1117823T1 (enrdf_load_stackoverflow)
DK (1) DK2739605T3 (enrdf_load_stackoverflow)
EA (1) EA024650B1 (enrdf_load_stackoverflow)
ES (1) ES2577177T3 (enrdf_load_stackoverflow)
HR (1) HRP20160767T1 (enrdf_load_stackoverflow)
HU (1) HUE030282T2 (enrdf_load_stackoverflow)
IN (1) IN2014CN00348A (enrdf_load_stackoverflow)
PL (1) PL2739605T3 (enrdf_load_stackoverflow)
PT (1) PT2739605E (enrdf_load_stackoverflow)
SI (1) SI2739605T1 (enrdf_load_stackoverflow)
WO (1) WO2013017903A1 (enrdf_load_stackoverflow)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104876830A (zh) * 2015-06-09 2015-09-02 江苏中邦制药有限公司 一种阿戈美拉汀i晶型晶体的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2658818B1 (fr) 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2866335B1 (fr) 2004-02-13 2006-05-26 Servier Lab Nouveau procede de synthese de l'agomelatine
EP2319827A1 (en) * 2009-11-09 2011-05-11 Ratiopharm GmbH Process for the production of polymorph form I of agomelatine
CN101704763B (zh) 2009-11-25 2012-03-28 天津泰普药品科技发展有限公司 阿戈美拉汀i型晶体的制备方法
CN101921205B (zh) * 2010-08-30 2013-11-20 江苏恩华药业股份有限公司 阿戈美拉汀ⅰ晶型的制备方法

Also Published As

Publication number Publication date
CN103827078A (zh) 2014-05-28
CY1117823T1 (el) 2017-05-17
PL2739605T3 (pl) 2016-11-30
EP2739605A1 (en) 2014-06-11
EA024650B1 (ru) 2016-10-31
WO2013017903A1 (en) 2013-02-07
SI2739605T1 (sl) 2016-08-31
US20150291508A1 (en) 2015-10-15
EP2739605B1 (en) 2016-04-27
PT2739605E (pt) 2016-06-20
CA2843827A1 (en) 2013-02-07
ES2577177T3 (es) 2016-07-13
HRP20160767T1 (hr) 2016-08-12
HUE030282T2 (en) 2017-05-29
BR112014002523A2 (pt) 2017-03-14
DK2739605T3 (en) 2016-07-25
CN103827078B (zh) 2015-08-05
EA201400188A1 (ru) 2014-07-30

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