CY1117823T1 - Μεθοδος για την παρασκευη κρυσταλλικης μορφης ι της αγομελατινης - Google Patents
Μεθοδος για την παρασκευη κρυσταλλικης μορφης ι της αγομελατινηςInfo
- Publication number
- CY1117823T1 CY1117823T1 CY20161100712T CY161100712T CY1117823T1 CY 1117823 T1 CY1117823 T1 CY 1117823T1 CY 20161100712 T CY20161100712 T CY 20161100712T CY 161100712 T CY161100712 T CY 161100712T CY 1117823 T1 CY1117823 T1 CY 1117823T1
- Authority
- CY
- Cyprus
- Prior art keywords
- agomelatin
- crystal form
- preparing crystal
- preparing
- freeze
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Abstract
Η εφεύρεση αφορά μια νέα μέθοδο για την παρασκευή κρυσταλλικής μορφής Ι της αγομελατίνης με ξήρανση με κατάψυξη.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IB2011/001805 WO2013017903A1 (en) | 2011-08-03 | 2011-08-03 | Process for the preparation of crystalline form i of agomelatine |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1117823T1 true CY1117823T1 (el) | 2017-05-17 |
Family
ID=44802320
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20161100712T CY1117823T1 (el) | 2011-08-03 | 2016-07-20 | Μεθοδος για την παρασκευη κρυσταλλικης μορφης ι της αγομελατινης |
Country Status (16)
Country | Link |
---|---|
US (1) | US20150291508A1 (el) |
EP (1) | EP2739605B1 (el) |
CN (1) | CN103827078B (el) |
BR (1) | BR112014002523A2 (el) |
CA (1) | CA2843827A1 (el) |
CY (1) | CY1117823T1 (el) |
DK (1) | DK2739605T3 (el) |
EA (1) | EA024650B1 (el) |
ES (1) | ES2577177T3 (el) |
HR (1) | HRP20160767T1 (el) |
HU (1) | HUE030282T2 (el) |
IN (1) | IN2014CN00348A (el) |
PL (1) | PL2739605T3 (el) |
PT (1) | PT2739605E (el) |
SI (1) | SI2739605T1 (el) |
WO (1) | WO2013017903A1 (el) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104876830A (zh) * | 2015-06-09 | 2015-09-02 | 江苏中邦制药有限公司 | 一种阿戈美拉汀i晶型晶体的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2658818B1 (fr) | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
FR2866335B1 (fr) | 2004-02-13 | 2006-05-26 | Servier Lab | Nouveau procede de synthese de l'agomelatine |
EP2319827A1 (en) | 2009-11-09 | 2011-05-11 | Ratiopharm GmbH | Process for the production of polymorph form I of agomelatine |
CN101704763B (zh) | 2009-11-25 | 2012-03-28 | 天津泰普药品科技发展有限公司 | 阿戈美拉汀i型晶体的制备方法 |
CN101921205B (zh) * | 2010-08-30 | 2013-11-20 | 江苏恩华药业股份有限公司 | 阿戈美拉汀ⅰ晶型的制备方法 |
-
2011
- 2011-08-03 PL PL11770507.9T patent/PL2739605T3/pl unknown
- 2011-08-03 US US14/236,772 patent/US20150291508A1/en not_active Abandoned
- 2011-08-03 PT PT117705079T patent/PT2739605E/pt unknown
- 2011-08-03 WO PCT/IB2011/001805 patent/WO2013017903A1/en active Application Filing
- 2011-08-03 BR BR112014002523A patent/BR112014002523A2/pt not_active Application Discontinuation
- 2011-08-03 CN CN201180072630.4A patent/CN103827078B/zh not_active Expired - Fee Related
- 2011-08-03 EP EP11770507.9A patent/EP2739605B1/en not_active Not-in-force
- 2011-08-03 EA EA201400188A patent/EA024650B1/ru not_active IP Right Cessation
- 2011-08-03 CA CA2843827A patent/CA2843827A1/en not_active Abandoned
- 2011-08-03 HU HUE11770507A patent/HUE030282T2/en unknown
- 2011-08-03 SI SI201130880A patent/SI2739605T1/sl unknown
- 2011-08-03 DK DK11770507.9T patent/DK2739605T3/en active
- 2011-08-03 ES ES11770507.9T patent/ES2577177T3/es active Active
- 2011-08-03 IN IN348CHN2014 patent/IN2014CN00348A/en unknown
-
2016
- 2016-06-30 HR HRP20160767TT patent/HRP20160767T1/hr unknown
- 2016-07-20 CY CY20161100712T patent/CY1117823T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO2013017903A1 (en) | 2013-02-07 |
PT2739605E (pt) | 2016-06-20 |
CN103827078A (zh) | 2014-05-28 |
SI2739605T1 (sl) | 2016-08-31 |
EA024650B1 (ru) | 2016-10-31 |
EP2739605A1 (en) | 2014-06-11 |
DK2739605T3 (en) | 2016-07-25 |
HUE030282T2 (en) | 2017-05-29 |
ES2577177T3 (es) | 2016-07-13 |
IN2014CN00348A (el) | 2015-04-03 |
EP2739605B1 (en) | 2016-04-27 |
BR112014002523A2 (pt) | 2017-03-14 |
EA201400188A1 (ru) | 2014-07-30 |
US20150291508A1 (en) | 2015-10-15 |
PL2739605T3 (pl) | 2016-11-30 |
HRP20160767T1 (hr) | 2016-08-12 |
CA2843827A1 (en) | 2013-02-07 |
CN103827078B (zh) | 2015-08-05 |
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