IN2013MU03491A - - Google Patents

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Publication number
IN2013MU03491A
IN2013MU03491A IN3491MU2013A IN2013MU03491A IN 2013MU03491 A IN2013MU03491 A IN 2013MU03491A IN 3491MU2013 A IN3491MU2013 A IN 3491MU2013A IN 2013MU03491 A IN2013MU03491 A IN 2013MU03491A
Authority
IN
India
Prior art keywords
treosulfan
relates
present
improved
methylsulfonyloxybutyl
Prior art date
Application number
Inventor
Sougata Pramanick
Vikram Shamrao Gharge
Krishna Barsu Kinage
Rushil Vidhyutbhai Shah
Mukund Keshav Gurjar
Samit Satish Mehta
Original Assignee
Emcure Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emcure Pharmaceuticals Ltd filed Critical Emcure Pharmaceuticals Ltd
Priority to IN3491MU2013 priority Critical patent/IN2013MU03491A/en
Priority to PCT/IN2014/000692 priority patent/WO2015107534A1/en
Publication of IN2013MU03491A publication Critical patent/IN2013MU03491A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Abstract

The present invention relates to an improved solid formulation of (2S,3S)-2,3-Dihydroxy-4-methylsulfonyloxybutyl] methanesulfonate. The improved formulations are lyophilized pharmaceutical solid composition containing treosulfan for reconstitution with water to provide a solution for parenteral administration. The present invention also relates to Polymorphic Form I and II of treosulfan.
IN3491MU2013 2013-11-04 2014-10-31 IN2013MU03491A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IN3491MU2013 IN2013MU03491A (en) 2013-11-04 2014-10-31
PCT/IN2014/000692 WO2015107534A1 (en) 2013-11-04 2014-10-31 Lyophilized formulation of treosulfan

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN3491MU2013 IN2013MU03491A (en) 2013-11-04 2014-10-31

Publications (1)

Publication Number Publication Date
IN2013MU03491A true IN2013MU03491A (en) 2015-07-31

Family

ID=53039936

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3491MU2013 IN2013MU03491A (en) 2013-11-04 2014-10-31

Country Status (2)

Country Link
IN (1) IN2013MU03491A (en)
WO (1) WO2015107534A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA202190615A1 (en) * 2018-09-26 2021-06-24 Медак Гезельшафт Фюр Клинише Шпециальпрепарате Мбх CRYSTAL FORM OF TREOSULPHANE
EP3856252A1 (en) 2018-09-26 2021-08-04 medac Gesellschaft für klinische Spezialpräparate mbH Solution comprising treosulfan
EP3856151B1 (en) * 2018-09-26 2023-08-23 medac Gesellschaft für klinische Spezialpräparate mbH Lyophilisate of treosulfan

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155702A (en) 1960-02-22 1964-11-03 Lphivens Kemiske Fabrik Ved A Stereoisomers and the racemate of butane-1, 2, 3, 4-tetrol-1, 4-di
ATE452896T1 (en) * 2002-03-12 2010-01-15 Bristol Myers Squibb Co C3-CYANOEPOTHILONE DERIVATIVES
WO2008135232A1 (en) * 2007-05-02 2008-11-13 Riccardo Cortese Use and compositions of purine derivatives for the treatment of proliferative disorders
DE102009022046A1 (en) * 2009-05-16 2010-11-18 Evoria Gmbh Decoloured extracts of the plant Pandanus conoideus

Also Published As

Publication number Publication date
WO2015107534A1 (en) 2015-07-23

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