IN2013MU03118A - - Google Patents
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- Publication number
- IN2013MU03118A IN2013MU03118A IN3118MU2013A IN2013MU03118A IN 2013MU03118 A IN2013MU03118 A IN 2013MU03118A IN 3118MU2013 A IN3118MU2013 A IN 3118MU2013A IN 2013MU03118 A IN2013MU03118 A IN 2013MU03118A
- Authority
- IN
- India
- Prior art keywords
- capecitabine
- cyclophosphamide
- processes
- preparation
- pharmaceutical compositions
- Prior art date
Links
- GAGWJHPBXLXJQN-UORFTKCHSA-N Capecitabine Chemical compound C1=C(F)C(NC(=O)OCCCCC)=NC(=O)N1[C@H]1[C@H](O)[C@H](O)[C@@H](C)O1 GAGWJHPBXLXJQN-UORFTKCHSA-N 0.000 abstract 1
- GAGWJHPBXLXJQN-UHFFFAOYSA-N Capecitabine Natural products C1=C(F)C(NC(=O)OCCCCC)=NC(=O)N1C1C(O)C(O)C(C)O1 GAGWJHPBXLXJQN-UHFFFAOYSA-N 0.000 abstract 1
- CMSMOCZEIVJLDB-UHFFFAOYSA-N Cyclophosphamide Chemical compound ClCCN(CCCl)P1(=O)NCCCO1 CMSMOCZEIVJLDB-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 229960004117 capecitabine Drugs 0.000 abstract 1
- 229940000425 combination drug Drugs 0.000 abstract 1
- 229960004397 cyclophosphamide Drugs 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/025,819 US20160243034A1 (en) | 2013-09-30 | 2014-09-29 | Pharmaceutical composition comprising capecitabine and cyclophosphamide |
| ES14850037T ES2753435T3 (es) | 2013-09-30 | 2014-09-29 | Composición farmacéutica que comprende capecitabina y ciclofosfamida |
| BR112016007031A BR112016007031A8 (pt) | 2013-09-30 | 2014-09-29 | composição farmacêutica oral sólida, processo para preparar a composição farmacêutica oral sólida, e uso de uma composição farcêutica oral sólida |
| MX2016004094A MX2016004094A (es) | 2013-09-30 | 2014-09-29 | Composicion farmaceutica que comprende capecitabina y ciclofosfamida. |
| CA2925960A CA2925960A1 (en) | 2013-09-30 | 2014-09-29 | Pharmaceutical composition comprising capecitabine and cyclophosphamide |
| AU2014326142A AU2014326142B2 (en) | 2013-09-30 | 2014-09-29 | Pharmaceutical composition comprising capecitabine and cyclophosphamide |
| EP14850037.4A EP3052130B1 (en) | 2013-09-30 | 2014-09-29 | Pharmaceutical composition comprising capecitabine and cyclophosphamide |
| PCT/IN2014/000625 WO2015044961A2 (en) | 2013-09-30 | 2014-09-29 | Pharmaceutical composition comprising capecitabine and cyclophosphamide |
| IN3118MU2013 IN2013MU03118A (h) | 2013-09-30 | 2014-09-29 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3118MU2013 IN2013MU03118A (h) | 2013-09-30 | 2014-09-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013MU03118A true IN2013MU03118A (h) | 2015-08-14 |
Family
ID=52744637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3118MU2013 IN2013MU03118A (h) | 2013-09-30 | 2014-09-29 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20160243034A1 (h) |
| EP (1) | EP3052130B1 (h) |
| AU (1) | AU2014326142B2 (h) |
| BR (1) | BR112016007031A8 (h) |
| CA (1) | CA2925960A1 (h) |
| ES (1) | ES2753435T3 (h) |
| IN (1) | IN2013MU03118A (h) |
| MX (1) | MX2016004094A (h) |
| WO (1) | WO2015044961A2 (h) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201613563A (en) * | 2014-06-12 | 2016-04-16 | Sanofi Synthelabo India Ltd | Bi-layer tablet formulations of cyclophosphamide and CAPECITABINE and highly fractionated METRONOMIC administration thereof |
| CA2958332A1 (en) | 2014-09-26 | 2016-03-31 | Intas Pharmaceuticals Ltd. | Pharmaceutical composition having improved content uniformity |
| SG11201809658UA (en) * | 2016-05-03 | 2018-11-29 | Intas Pharmaceuticals Ltd | Tablet-in-tablet pharmaceutical composition comprising cyclophosphamide and capecitabine |
| CN115666516A (zh) * | 2020-06-01 | 2023-01-31 | 希尔帕医疗保健有限公司 | 包括卡培他滨的快速分散药物组合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5047246A (en) * | 1988-09-09 | 1991-09-10 | Bristol-Myers Company | Direct compression cyclophosphamide tablet |
| EP2032168A4 (en) * | 2006-06-02 | 2010-12-29 | Ariad Pharma Inc | COMBINED THERAPY BASED ON CAPECITABINE |
| AU2010250800A1 (en) * | 2009-05-20 | 2012-01-12 | Ranbaxy Laboratories Limited | Oral compositions of celecoxib |
| EP2747571A4 (en) * | 2011-08-24 | 2015-05-27 | David Kerr | COMBINED COMBINED CHEMOTHERAPY |
| CN103251569B (zh) * | 2013-05-30 | 2015-10-28 | 成都苑东药业有限公司 | 卡培他滨片组合物及其制备方法 |
-
2014
- 2014-09-29 AU AU2014326142A patent/AU2014326142B2/en not_active Ceased
- 2014-09-29 EP EP14850037.4A patent/EP3052130B1/en active Active
- 2014-09-29 CA CA2925960A patent/CA2925960A1/en not_active Abandoned
- 2014-09-29 WO PCT/IN2014/000625 patent/WO2015044961A2/en active Application Filing
- 2014-09-29 IN IN3118MU2013 patent/IN2013MU03118A/en unknown
- 2014-09-29 ES ES14850037T patent/ES2753435T3/es active Active
- 2014-09-29 MX MX2016004094A patent/MX2016004094A/es unknown
- 2014-09-29 BR BR112016007031A patent/BR112016007031A8/pt not_active IP Right Cessation
- 2014-09-29 US US15/025,819 patent/US20160243034A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BR112016007031A8 (pt) | 2020-02-27 |
| EP3052130B1 (en) | 2019-08-07 |
| WO2015044961A2 (en) | 2015-04-02 |
| EP3052130A4 (en) | 2017-05-31 |
| US20160243034A1 (en) | 2016-08-25 |
| EP3052130A2 (en) | 2016-08-10 |
| AU2014326142B2 (en) | 2019-07-25 |
| MX2016004094A (es) | 2016-10-28 |
| AU2014326142A1 (en) | 2016-04-21 |
| CA2925960A1 (en) | 2015-04-02 |
| ES2753435T3 (es) | 2020-04-08 |
| BR112016007031A2 (pt) | 2017-08-01 |
| WO2015044961A3 (en) | 2015-06-04 |
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