IN2013MN01394A - - Google Patents

Download PDF

Info

Publication number
IN2013MN01394A
IN2013MN01394A IN1394MUN2013A IN2013MN01394A IN 2013MN01394 A IN2013MN01394 A IN 2013MN01394A IN 1394MUN2013 A IN1394MUN2013 A IN 1394MUN2013A IN 2013MN01394 A IN2013MN01394 A IN 2013MN01394A
Authority
IN
India
Prior art keywords
alphabodies
polypeptides
nucleic acids
host cells
compositions
Prior art date
Application number
Other languages
English (en)
Inventor
Ignace Lasters
Johan Desmet
Maria Henderikx
Anita Wehnert
Geert Meersseman
Original Assignee
Complix Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Complix Nv filed Critical Complix Nv
Publication of IN2013MN01394A publication Critical patent/IN2013MN01394A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2318/00—Antibody mimetics or scaffolds
    • C07K2318/20—Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IN1394MUN2013 2011-01-06 2012-01-06 IN2013MN01394A (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2011050138 2011-01-06
PCT/EP2012/050193 WO2012093172A1 (en) 2011-01-06 2012-01-06 Alphabodies specifically binding to cytokines or growth factors and/or cytokine or growth factor receptors

Publications (1)

Publication Number Publication Date
IN2013MN01394A true IN2013MN01394A (ro) 2015-06-12

Family

ID=44242740

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1394MUN2013 IN2013MN01394A (ro) 2011-01-06 2012-01-06

Country Status (9)

Country Link
US (1) US20140057830A1 (ro)
JP (1) JP2014504869A (ro)
CN (1) CN103339148A (ro)
AU (1) AU2012204846B2 (ro)
BR (1) BR112013017367A2 (ro)
CA (1) CA2821646A1 (ro)
DK (1) DK2661447T3 (ro)
IN (1) IN2013MN01394A (ro)
WO (1) WO2012093172A1 (ro)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2668210T3 (da) 2011-01-26 2020-08-24 Celldex Therapeutics Inc Anti-kit antistoffer og anvendelser deraf
WO2013102659A2 (en) 2012-01-06 2013-07-11 Complix Nv Binding agents to intracellular target molecules
CN116574185A (zh) 2012-07-25 2023-08-11 塞尔德克斯医疗公司 抗kit抗体及其用途
CA2888930C (en) 2012-10-22 2020-10-20 Complix Nv Polypeptides capable of cellular internalization
WO2014064080A1 (en) 2012-10-22 2014-05-01 Complix Nv Polypeptides specifically binding to il-23
CN113908269A (zh) 2014-05-23 2022-01-11 塞尔德克斯医疗公司 嗜酸性粒细胞或肥大细胞相关病症的治疗
WO2017102835A1 (en) * 2015-12-14 2017-06-22 Complix Nv Binding molecule comprising an alphabody-polypeptide and an antibody
CN113315431B (zh) * 2021-04-22 2023-07-28 湖南工业大学 基于等价输入干扰系统的pmsm失磁故障控制方法、电机
CN114544812B (zh) * 2022-02-18 2023-06-30 复旦大学附属中山医院 一种代谢组合式标志物在诊断哮喘中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101323643B (zh) * 2007-06-15 2010-12-01 烟台荣昌生物工程有限公司 优化的TACI-Fc融合蛋白
EP2161278B1 (en) * 2008-09-08 2012-05-23 Complix N.V. Single-chain coiled coil scaffold
CN102245623A (zh) * 2008-12-08 2011-11-16 康普里斯有限公司 单链反向平行卷曲型螺旋蛋白
EP2661446B1 (en) * 2011-01-06 2015-09-30 Complix SA Alphabody libraries and methods for producing the same

Also Published As

Publication number Publication date
CN103339148A (zh) 2013-10-02
US20140057830A1 (en) 2014-02-27
JP2014504869A (ja) 2014-02-27
BR112013017367A2 (pt) 2016-11-22
AU2012204846B2 (en) 2016-09-08
DK2661447T3 (en) 2015-11-02
AU2012204846A1 (en) 2013-07-04
CA2821646A1 (en) 2012-07-12
WO2012093172A1 (en) 2012-07-12

Similar Documents

Publication Publication Date Title
IN2013MN01394A (ro)
EA201290567A1 (ru) Получение гетерологичных полипептидов в микроводорослях, внеклеточные микроводорослевые тельца, композиции и способы их получения и применения
PH12014501912A1 (en) Cx3cr1-binding polypeptides
PH12019500441A1 (en) Monoclonal antibodies against tissue factor pathway inhibitor (tfpi)
TN2014000438A1 (en) Anti-fcrn antibodies
MX346923B (es) Genes y proteinas para sintesis de alcanoil-coa.
ZA201400490B (en) Arginine- free tnfr: fc- fusion polypeptide compositions and methods of use
IN2014MN01562A (ro)
MX2015007921A (es) Compuestos heterociclicos novedosos como inhibidores de bromodominio.
MX2012011771A (es) Aptameros para beta-ngf y su uso en el tratamiento de enfermedades y trastornos mediados por beta-ngf.
TN2012000512A1 (en) Compositions and methods of use for therapeutic low density lipoprotein - related protein 6 (lrp6) multivalent antibodies
HK1255729A1 (zh) 包含針對pcsk9的人抗體的藥物組合物
MY162737A (en) 4-1bb binding molecules
CA2818969A1 (en) Improved n-terminal capping modules for designed ankyrin repeat proteins
SG194469A1 (en) Tetrahydroquinoline derivatives useful as bromodomain inhibitors
MX2013003681A (es) Ácidos nucleicos manipulados y métodos de uso de los mismos.
TN2012000511A1 (en) Compositions and methods of use for therapeutic low density lipoprotein -related protein 6 (lrp6) antibodies
MX361874B (es) Anticuerpos frente a los ligandos del receptor b1 de bradicinina.
EP2855503A4 (en) METHOD OF USE OF MIXED MULTIFUNCTIONAL SURFACES TO REDUCE THE AGGREGATE CONTENT IN PROTEIN PREPARATIONS
MX366178B (es) Proteinas de btnl3, acidos nucleicos, y anticuerpos y los usos de los mismos.
EP2744480A4 (en) GELIFYING COMPOSITIONS WITH LOW PROTEIN CONCENTRATION
MX2014010958A (es) Composicion de celulas inmunoestimuladora activada y sus usos.
IL261409A (en) Methods and compositions for production of recombinant pharmaceutical proteins in medicinal plants
TN2014000395A1 (en) Antibodies to bradykinin b1 receptor ligands