IN2013DE02892A - - Google Patents
Info
- Publication number
- IN2013DE02892A IN2013DE02892A IN2892DE2013A IN2013DE02892A IN 2013DE02892 A IN2013DE02892 A IN 2013DE02892A IN 2892DE2013 A IN2892DE2013 A IN 2892DE2013A IN 2013DE02892 A IN2013DE02892 A IN 2013DE02892A
- Authority
- IN
- India
- Prior art keywords
- groups
- relates
- lower alkyl
- collagen
- platelet
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 239000003146 anticoagulant agent Substances 0.000 abstract 3
- 102000008186 Collagen Human genes 0.000 abstract 2
- 108010035532 Collagen Proteins 0.000 abstract 2
- 230000000702 anti-platelet effect Effects 0.000 abstract 2
- 229920001436 collagen Polymers 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 abstract 2
- CKXUBCFMNGAALX-UHFFFAOYSA-N C12(CNCC(CNC1)C2)C(=O)N Chemical class C12(CNCC(CNC1)C2)C(=O)N CKXUBCFMNGAALX-UHFFFAOYSA-N 0.000 abstract 1
- 102000009268 Collagen Receptors Human genes 0.000 abstract 1
- 108010048623 Collagen Receptors Proteins 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229940122119 Thromboxane receptor agonist Drugs 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 230000009977 dual effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
- 125000005931 tert-butyloxycarbonyl group Chemical group [H]C([H])([H])C(OC(*)=O)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- 239000003767 thromboxane receptor stimulating agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2014/000458 WO2015044951A1 (en) | 2013-09-30 | 2014-07-09 | 3,7-diazabicyclo[3.3.1 ]nonane carboxamides as antithrombotic agents |
| EP14759059.0A EP3052498A1 (en) | 2013-09-30 | 2014-07-09 | 3,7-diazabicyclo[3.3.1]nonane carboxamides as antithrombotic agents |
| IN2892DE2013 IN2013DE02892A (cs) | 2013-09-30 | 2014-07-09 | |
| US15/025,864 US20160214983A1 (en) | 2013-09-30 | 2014-07-09 | 3,7-diazabicyclo[3.3.1]nonane carboxamides as antithrombotic agents |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2892DE2013 IN2013DE02892A (cs) | 2013-09-30 | 2014-07-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013DE02892A true IN2013DE02892A (cs) | 2015-04-03 |
Family
ID=51485809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2892DE2013 IN2013DE02892A (cs) | 2013-09-30 | 2014-07-09 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20160214983A1 (cs) |
| EP (1) | EP3052498A1 (cs) |
| IN (1) | IN2013DE02892A (cs) |
| WO (1) | WO2015044951A1 (cs) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9602263D0 (sv) | 1996-06-07 | 1996-06-07 | Astra Ab | New amino acid derivatives |
| SE9902270D0 (sv) | 1999-06-16 | 1999-06-16 | Astra Ab | Pharmaceutically active compounds |
| WO2012104866A1 (en) * | 2011-01-31 | 2012-08-09 | Council Of Scientific & Industrial Research | Chiral 1-(4-methylphenylmethyl)-5-oxo-{n-[(3-t-butoxycarbonyl- aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamides as inhibitors of collagen induced platelet activation and adhesion |
-
2014
- 2014-07-09 IN IN2892DE2013 patent/IN2013DE02892A/en unknown
- 2014-07-09 WO PCT/IN2014/000458 patent/WO2015044951A1/en not_active Ceased
- 2014-07-09 EP EP14759059.0A patent/EP3052498A1/en not_active Withdrawn
- 2014-07-09 US US15/025,864 patent/US20160214983A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015044951A1 (en) | 2015-04-02 |
| EP3052498A1 (en) | 2016-08-10 |
| US20160214983A1 (en) | 2016-07-28 |
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| IN2013DE02892A (cs) |