IN2013DE01960A - - Google Patents
Info
- Publication number
- IN2013DE01960A IN2013DE01960A IN1960DE2013A IN2013DE01960A IN 2013DE01960 A IN2013DE01960 A IN 2013DE01960A IN 1960DE2013 A IN1960DE2013 A IN 1960DE2013A IN 2013DE01960 A IN2013DE01960 A IN 2013DE01960A
- Authority
- IN
- India
- Prior art keywords
- chikungunya virus
- seq
- rnai agents
- inhibition
- nspl
- Prior art date
Links
- 241001502567 Chikungunya virus Species 0.000 abstract 5
- 108091030071 RNAI Proteins 0.000 abstract 5
- 230000009368 gene silencing by RNA Effects 0.000 abstract 5
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- 230000005764 inhibitory process Effects 0.000 abstract 3
- 239000002773 nucleotide Substances 0.000 abstract 3
- 125000003729 nucleotide group Chemical group 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 208000004293 Chikungunya Fever Diseases 0.000 abstract 1
- 206010067256 Chikungunya virus infection Diseases 0.000 abstract 1
- 101150082674 E2 gene Proteins 0.000 abstract 1
- 101710125507 Integrase/recombinase Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000029812 viral genome replication Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2014/000441 WO2015001570A1 (en) | 2013-07-02 | 2014-07-02 | Rnai agent for inhibition of chikungunya virus |
| US14/899,135 US9574195B2 (en) | 2013-07-02 | 2014-07-02 | RNAi agent for inhibition of Chikungunya virus |
| CN201480037556.6A CN105392886B (zh) | 2013-07-02 | 2014-07-02 | 用于抑制切昆贡亚病毒的RNAi剂 |
| IN1960DE2013 IN2013DE01960A (enrdf_load_stackoverflow) | 2013-07-02 | 2014-07-02 | |
| EP14753163.6A EP3017046B1 (en) | 2013-07-02 | 2014-07-02 | Rnai agent for inhibition of chikungunya virus |
| AU2014285701A AU2014285701C1 (en) | 2013-07-02 | 2014-07-02 | RNAi agent for inhibition of Chikungunya virus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1960DE2013 IN2013DE01960A (enrdf_load_stackoverflow) | 2013-07-02 | 2014-07-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013DE01960A true IN2013DE01960A (enrdf_load_stackoverflow) | 2015-06-26 |
Family
ID=51383914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1960DE2013 IN2013DE01960A (enrdf_load_stackoverflow) | 2013-07-02 | 2014-07-02 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9574195B2 (enrdf_load_stackoverflow) |
| EP (1) | EP3017046B1 (enrdf_load_stackoverflow) |
| CN (1) | CN105392886B (enrdf_load_stackoverflow) |
| AU (1) | AU2014285701C1 (enrdf_load_stackoverflow) |
| IN (1) | IN2013DE01960A (enrdf_load_stackoverflow) |
| WO (1) | WO2015001570A1 (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110832077B (zh) * | 2017-07-06 | 2025-01-03 | 箭头药业股份有限公司 | 用于抑制α-ENaC表达的RNAi剂及使用方法 |
-
2014
- 2014-07-02 AU AU2014285701A patent/AU2014285701C1/en active Active
- 2014-07-02 WO PCT/IN2014/000441 patent/WO2015001570A1/en active Application Filing
- 2014-07-02 CN CN201480037556.6A patent/CN105392886B/zh active Active
- 2014-07-02 EP EP14753163.6A patent/EP3017046B1/en active Active
- 2014-07-02 US US14/899,135 patent/US9574195B2/en active Active
- 2014-07-02 IN IN1960DE2013 patent/IN2013DE01960A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20160145621A1 (en) | 2016-05-26 |
| AU2014285701C1 (en) | 2021-07-15 |
| US9574195B2 (en) | 2017-02-21 |
| AU2014285701A1 (en) | 2016-01-21 |
| EP3017046B1 (en) | 2019-09-11 |
| CN105392886A (zh) | 2016-03-09 |
| AU2014285701B2 (en) | 2021-04-01 |
| CN105392886B (zh) | 2019-10-22 |
| WO2015001570A1 (en) | 2015-01-08 |
| EP3017046A1 (en) | 2016-05-11 |
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