IN2013CN00459A - - Google Patents

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Publication number
IN2013CN00459A
IN2013CN00459A IN459CHN2013A IN2013CN00459A IN 2013CN00459 A IN2013CN00459 A IN 2013CN00459A IN 459CHN2013 A IN459CHN2013 A IN 459CHN2013A IN 2013CN00459 A IN2013CN00459 A IN 2013CN00459A
Authority
IN
India
Prior art keywords
dicarboxylic acid
methods
relates
present
dicarboxylic
Prior art date
Application number
Inventor
Sheryl Luttringer
Debbie Yaver
Original Assignee
Novozymes Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes Inc filed Critical Novozymes Inc
Publication of IN2013CN00459A publication Critical patent/IN2013CN00459A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to methods of producing C4 dicarboxylic acids such as malic acid comprising: (a) cultivating a host cell comprising a polynucleotide encoding a C4 dicarboxylic acid transporter; and (b) recovering the C4 dicarboxylic acid. The present invention also relates to methods for increasing C4 dicarboxylic acid production as well as host cells comprising the polynucleotides.
IN459CHN2013 2010-06-21 2011-06-21 IN2013CN00459A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35700710P 2010-06-21 2010-06-21
PCT/US2011/041301 WO2011163270A1 (en) 2010-06-21 2011-06-21 Methods for improved c4-dicarboxylic acid production in filamentous fungi

Publications (1)

Publication Number Publication Date
IN2013CN00459A true IN2013CN00459A (en) 2015-07-03

Family

ID=44504321

Family Applications (1)

Application Number Title Priority Date Filing Date
IN459CHN2013 IN2013CN00459A (en) 2010-06-21 2011-06-21

Country Status (6)

Country Link
US (2) US8497103B2 (en)
EP (1) EP2582829B1 (en)
CN (1) CN102947458B (en)
BR (1) BR112012028031A2 (en)
IN (1) IN2013CN00459A (en)
WO (1) WO2011163270A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011028643A1 (en) * 2009-09-01 2011-03-10 Novozymes, Inc. Methods for improving malic acid production in filamentous fungi
WO2014142647A1 (en) * 2013-03-14 2014-09-18 Wageningen Universiteit Fungals strains with improved citric acid and itaconic acid production
WO2015200545A1 (en) 2014-06-26 2015-12-30 Lygos, Inc. Recombinant host cells for the production of malonate
WO2016127920A1 (en) * 2015-02-15 2016-08-18 中国科学院天津工业生物技术研究所 New dibasic organic acid producing strain and preparation and application of same
CN106148208B (en) * 2015-03-23 2020-12-18 中国科学院天津工业生物技术研究所 Novel binary organic acid producing strain and preparation and application thereof
CN106148209B (en) * 2015-03-23 2020-11-20 中国科学院天津工业生物技术研究所 Novel binary organic acid producing strain and preparation and application thereof
JP6637712B2 (en) * 2015-10-13 2020-01-29 花王株式会社 Method for producing C4 dicarboxylic acid
CN105754963A (en) * 2016-05-19 2016-07-13 江南大学 Method for improving yield of fumaric acid
JP6970101B2 (en) * 2016-09-15 2021-11-24 花王株式会社 Mutant filamentous fungus and a method for producing a C4 dicarboxylic acid using the mutant filamentous fungus.
CN114806899B (en) * 2022-04-14 2024-04-02 王玮 Trichoderma reesei engineering bacteria for producing L-malic acid and application thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1047002A (en) 1911-04-03 1912-12-10 James S Diehl Scissors.
US3063910A (en) 1960-02-03 1962-11-13 Kyowa Hakko Kogyo Kk Method of producing l-malic acid by fermentation
US5536661A (en) 1987-03-10 1996-07-16 Novo Nordisk A/S Process for the production of protein products in aspergillus
DK122686D0 (en) 1986-03-17 1986-03-17 Novo Industri As PREPARATION OF PROTEINS
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE4343591A1 (en) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Process for the evolutionary design and synthesis of functional polymers based on shape elements and shape codes
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
ATE206460T1 (en) 1994-06-03 2001-10-15 Novo Nordisk Biotech Inc PURIFIED MYCELIOPTHHORA LACCASES AND NUCLEIC ACIDS CODING THEREOF
WO1996000787A1 (en) 1994-06-30 1996-01-11 Novo Nordisk Biotech, Inc. Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein
US5766439A (en) 1996-10-10 1998-06-16 A. E. Staley Manufacturing Co. Production and recovery of organic acids
US7504490B1 (en) * 1998-10-16 2009-03-17 Oscient Pharmaceuticals Corporation Nucleic acid and amino acid sequences relating to Apergillus fumigatus for diagnostics and therapeutics
AU6188599A (en) 1998-10-26 2000-05-15 Novozymes A/S Constructing and screening a dna library of interest in filamentous fungal cells
WO2000056900A2 (en) 1999-03-22 2000-09-28 Novo Nordisk Biotech, Inc. Promoter sequences derived from fusarium venenatum and uses thereof
MX306561B (en) 2004-01-29 2013-01-09 Zeachem Inc Recovery of organic acids.
US20080090273A1 (en) * 2005-11-21 2008-04-17 Aaron Adriaan Winkler Malic Acid Production in Recombinant Yeast
EP2158323A4 (en) 2007-05-18 2011-06-22 Microbia Prec Engineering Inc Organic acid production by fungal cells
WO2008144626A1 (en) 2007-05-18 2008-11-27 Microbia Precision Engineering, Inc. Malic acid production in recombinant yeast
WO2009065778A1 (en) 2007-11-20 2009-05-28 Dsm Ip Assets B.V. Succinic acid production in a eukaryotic cell
WO2009155382A1 (en) 2008-06-17 2009-12-23 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
BRPI0915534B1 (en) 2008-07-08 2021-04-20 Dsm Ip Assets B.V. low ph succinic acid production
WO2010111344A2 (en) 2009-03-24 2010-09-30 Microbia, Inc. Methods and microorganisms for production of c4-dicarboxylic acids
JP2012223091A (en) 2009-08-25 2012-11-15 Ajinomoto Co Inc Method for producing l-amino acid
WO2011028643A1 (en) 2009-09-01 2011-03-10 Novozymes, Inc. Methods for improving malic acid production in filamentous fungi
WO2011066304A2 (en) 2009-11-25 2011-06-03 Codexis, Inc. Engineered beta-class carbonic anhydrase polypeptides and uses thereof

Also Published As

Publication number Publication date
BR112012028031A2 (en) 2019-09-24
WO2011163270A1 (en) 2011-12-29
US20130288321A1 (en) 2013-10-31
US8497103B2 (en) 2013-07-30
CN102947458B (en) 2016-05-04
EP2582829B1 (en) 2016-11-30
CN102947458A (en) 2013-02-27
EP2582829A1 (en) 2013-04-24
US20110312046A1 (en) 2011-12-22

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