IN2012DN02046A - - Google Patents

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Publication number
IN2012DN02046A
IN2012DN02046A IN2046DEN2012A IN2012DN02046A IN 2012DN02046 A IN2012DN02046 A IN 2012DN02046A IN 2046DEN2012 A IN2046DEN2012 A IN 2046DEN2012A IN 2012DN02046 A IN2012DN02046 A IN 2012DN02046A
Authority
IN
India
Prior art keywords
tvemps
compositions
mammal
methods
present specification
Prior art date
Application number
Inventor
P S Jacky Birgitte
E Garay Patton
Molina Yanira
G Stathakis Dean
Francis Joseph
Roger Aoki Kei
Fernandez-Salas Ester
E Steward Lance
Ghanshani Sanjiv
J Hunt Terrence
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of IN2012DN02046A publication Critical patent/IN2012DN02046A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893—Botulinum neurotoxin (3.4.24.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating cancer in a mammal using such TVEMP compositions.
IN2046DEN2012 2009-08-14 2010-08-16 IN2012DN02046A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23394709P 2009-08-14 2009-08-14
PCT/US2010/045659 WO2011020115A2 (en) 2009-08-14 2010-08-16 Methods of treating cancer using growth factor retargeted endopeptidases

Publications (1)

Publication Number Publication Date
IN2012DN02046A true IN2012DN02046A (en) 2015-08-21

Family

ID=43478303

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2046DEN2012 IN2012DN02046A (en) 2009-08-14 2010-08-16

Country Status (9)

Country Link
US (2) US20110070186A1 (en)
EP (1) EP2464366A2 (en)
KR (1) KR20140015129A (en)
CN (1) CN102971001A (en)
AU (1) AU2010282274A1 (en)
CA (1) CA2771181A1 (en)
IL (1) IL218066A0 (en)
IN (1) IN2012DN02046A (en)
WO (1) WO2011020115A2 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
US20100303757A1 (en) * 2009-05-29 2010-12-02 Allergan, Inc. Methods of Treating Chronic Neurogenic Inflammation Using Interleukin Retargeted Endopepidases
WO2013033680A1 (en) 2011-09-02 2013-03-07 Lifenet Health Bmp peptides & methods of use
US11078248B2 (en) 2010-03-19 2021-08-03 Lifenet Health BMP peptides and methods of use
AU2011315962B2 (en) 2010-10-14 2016-06-02 Allergan, Inc. Targeted delivery of Targeted Exocytosis Modulators to the sphenopalatine ganglion for treatment of headache disorders
WO2012112422A1 (en) * 2011-02-14 2012-08-23 Allergan, Inc. Inhibiting aberrant blood vessel formation using growth factor retargeted endopeptidases
US20120244188A1 (en) 2011-03-25 2012-09-27 Allergan, Inc. Treatment of Sensory Disturbance Disorders
US20120251573A1 (en) 2011-03-28 2012-10-04 Allergan, Inc. Endopeptidase Treatment of Neuroendocrine Disorders
US20120251574A1 (en) 2011-03-28 2012-10-04 Allergan, Inc. Endopeptidase and Neurotoxin Combination Treatment of Multiple Medical Conditions
US20120251575A1 (en) 2011-03-28 2012-10-04 Allergan, Inc. Endopeptidase Treatment of Involuntary Movement Disorders
US20120251518A1 (en) 2011-03-29 2012-10-04 Allergan, Inc. Endopeptidase Treatment of Sexual Dysfunction Disorders
US20120251519A1 (en) 2011-03-29 2012-10-04 Allergan, Inc. Endopeptidase Treatment of Smooth Muscle Disorders
US20120251515A1 (en) 2011-03-29 2012-10-04 Allergan, Inc. Endopeptidase Treatment of Cosmesis Disorders
US20120258132A1 (en) 2011-03-29 2012-10-11 Allergan, Inc. Vagal Nerve-Based Disorders
AR086245A1 (en) * 2011-05-02 2013-11-27 Baxter Int FIBRINE-UNION FIBRINE PEPTIDES
WO2012174123A1 (en) 2011-06-13 2012-12-20 Allergan, Inc. Treatment of psychological trauma
US20130171122A1 (en) 2011-12-29 2013-07-04 Allergan, Inc. Endopeptidase and neurotoxin combination treatment of bladder disorders
WO2014100019A1 (en) 2012-12-18 2014-06-26 Allergan, Inc. Prophylactic treatment of herpes recurrence
CN104634982B (en) * 2013-11-06 2016-08-17 中国科学院上海生命科学研究院 VEGF-C purposes in preparation septicemia and serious bacterial infections diagnostic reagent
KR102471057B1 (en) * 2014-09-16 2022-11-28 리제너론 파아마슈티컬스, 인크. Predictive and prognostic biomarkers related to anti-angiogenic therapy of metastatic colorectal cancer
JP6991863B2 (en) 2015-03-03 2022-02-03 カヴァ ヘルスケア インコーポレイテッド Modulation of cancer immunity by type 2 innate lymphoid cells, interleukin 33, and / or interferon-inducible protein 44
CN108070651A (en) * 2016-11-07 2018-05-25 苏州安康盟医疗科技有限公司 A kind of diagnostic analysis/prognostic analysis method for assessing CRC risks of recurrence
KR102277147B1 (en) * 2017-12-13 2021-07-13 건국대학교 산학협력단 Use of peptides derived from fibroblast growth factor to promote osteogenic or chondrogenic differentiation
WO2018141313A2 (en) * 2018-04-17 2018-08-09 Novo Nordisk A/S Uses of fgf-4 compounds
GB201900621D0 (en) * 2019-01-16 2019-03-06 Ipsen Biopharm Ltd Labelled polypeptides
CN114075272B (en) * 2020-08-10 2023-09-22 杭州俊丰生物工程有限公司 Preparation method of human neuregulin 4
CN113621690B (en) * 2021-07-26 2023-08-22 山西医科大学 Application of interleukin 32 as target in screening and targeting medicine for treating esophageal squamous carcinoma
CN114295839A (en) * 2021-08-11 2022-04-08 首都医科大学附属北京地坛医院 Application of HOXB7 protein in preparation of kit for identifying oligodendroglioma and astrocytoma

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6146886A (en) 1994-08-19 2000-11-14 Ribozyme Pharmaceuticals, Inc. RNA polymerase III-based expression of therapeutic RNAs
US6395713B1 (en) 1997-07-23 2002-05-28 Ribozyme Pharmaceuticals, Inc. Compositions for the delivery of negatively charged molecules
US7740868B2 (en) 1999-08-25 2010-06-22 Allergan, Inc. Activatable clostridial toxins
US20080032931A1 (en) * 1999-08-25 2008-02-07 Steward Lance E Activatable clostridial toxins
US7838008B2 (en) * 1999-12-07 2010-11-23 Allergan, Inc. Methods for treating diverse cancers
US6726918B1 (en) 2000-07-05 2004-04-27 Oculex Pharmaceuticals, Inc. Methods for treating inflammation-mediated conditions of the eye
US6899717B2 (en) 2002-09-18 2005-05-31 Allergan, Inc. Methods and apparatus for delivery of ocular implants
US20040137059A1 (en) 2003-01-09 2004-07-15 Thierry Nivaggioli Biodegradable ocular implant
US20060182783A1 (en) 2004-04-30 2006-08-17 Allergan, Inc. Sustained release intraocular drug delivery systems
WO2006059093A2 (en) * 2004-12-01 2006-06-08 Health Protection Agency Fusion proteins
AU2005311098B2 (en) 2004-12-01 2011-08-11 Allergan, Inc. Non-cytotoxic protein conjugates
WO2006101809A1 (en) * 2005-03-15 2006-09-28 Allergan, Inc. Modified clostridial toxins with enhanced targeting capabilities for endogenous clostridial toxin receptor systems
US7993656B2 (en) * 2006-07-11 2011-08-09 Allergan, Inc. Modified clostridial toxins with enhanced translocation capabilities and altered targeting activity for clostridial toxin target cells

Also Published As

Publication number Publication date
CN102971001A (en) 2013-03-13
KR20140015129A (en) 2014-02-06
AU2010282274A1 (en) 2012-03-15
IL218066A0 (en) 2012-04-30
EP2464366A2 (en) 2012-06-20
US20110070186A1 (en) 2011-03-24
WO2011020115A2 (en) 2011-02-17
WO2011020115A3 (en) 2013-04-04
CA2771181A1 (en) 2011-02-17
US20130195838A1 (en) 2013-08-01

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