IN2012DN01985A - - Google Patents
Info
- Publication number
- IN2012DN01985A IN2012DN01985A IN1985DEN2012A IN2012DN01985A IN 2012DN01985 A IN2012DN01985 A IN 2012DN01985A IN 1985DEN2012 A IN1985DEN2012 A IN 1985DEN2012A IN 2012DN01985 A IN2012DN01985 A IN 2012DN01985A
- Authority
- IN
- India
- Prior art keywords
- independently
- group
- lower alkyl
- linked
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Quinoline Compounds (AREA)
- Pyridine Compounds (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
The present invention provides a novel diazepine compound that blocks the Ikw current or the Kv1.5 channel potently and more selectively than other K+ channels. The present invention relates to a diazepine com¬pound represented by General Formula (1) or a salt thereof; wherein R1, R2, R3, and R4 are each independently hydrogen, lower alkyl, cy¬clo lower alkyl or lower alkoxy lower alkyl; R2 and R3 may be linked to form lower alky-lene; A1 is lower alkylene optionally substitut¬ed with one or more substiruents selected from the group consisting of hydroxyl and oxo; Y1 and Y2 are each independently -N= or -CH=; and R5 is group represented by (2) wherein R6 and R7 are each independently hy- ' drogen or organic group; R6 and R7 may be linked to form a ring together with the neigh¬boring group -XA-N-XB-; XA and XB are each independently a bond, lower alkylene, etc.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23597309P | 2009-08-21 | 2009-08-21 | |
US23598309P | 2009-08-21 | 2009-08-21 | |
US23598109P | 2009-08-21 | 2009-08-21 | |
US35968610P | 2010-06-29 | 2010-06-29 | |
PCT/JP2010/064545 WO2011021726A2 (en) | 2009-08-21 | 2010-08-20 | Nitrogen-containing compound and pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN01985A true IN2012DN01985A (en) | 2015-07-24 |
Family
ID=43014533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN1985DEN2012 IN2012DN01985A (en) | 2009-08-21 | 2010-08-20 |
Country Status (25)
Country | Link |
---|---|
US (3) | US8822453B2 (en) |
EP (3) | EP2727917A1 (en) |
JP (2) | JP5769700B2 (en) |
KR (1) | KR20120081973A (en) |
CN (1) | CN102482234B (en) |
AR (1) | AR078098A1 (en) |
AU (2) | AU2010285621A1 (en) |
CA (1) | CA2771579A1 (en) |
CO (1) | CO6440511A2 (en) |
DK (1) | DK2467364T3 (en) |
ES (1) | ES2477221T3 (en) |
HK (1) | HK1167391A1 (en) |
HR (1) | HRP20140636T1 (en) |
IL (2) | IL217101A0 (en) |
IN (1) | IN2012DN01985A (en) |
MX (1) | MX2012002149A (en) |
NZ (1) | NZ598918A (en) |
PL (1) | PL2467364T3 (en) |
PT (1) | PT2467364E (en) |
RU (1) | RU2012110553A (en) |
SG (1) | SG177316A1 (en) |
SI (1) | SI2467364T1 (en) |
TW (1) | TWI481601B (en) |
WO (1) | WO2011021726A2 (en) |
ZA (1) | ZA201201025B (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN2012DN00986A (en) * | 2009-08-21 | 2015-04-10 | Otsuka Pharma Co Ltd | |
US9738606B2 (en) * | 2011-06-03 | 2017-08-22 | Queen's University At Kingston | Substituted diarylamines and use of same as antioxidants |
US8940742B2 (en) | 2012-04-10 | 2015-01-27 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
CN102627597B (en) * | 2012-04-25 | 2013-10-23 | 山东轻工业学院 | Indole-3-carboxaldehyde isobutyryl hydrazone derivatives and preparation method thereof |
US9849127B2 (en) | 2013-05-14 | 2017-12-26 | Medizinisch Hochschule Hannover | Means and methods for treating cancer |
MX2016004340A (en) | 2013-10-04 | 2016-08-08 | Infinity Pharmaceuticals Inc | Heterocyclic compounds and uses thereof. |
WO2015051241A1 (en) | 2013-10-04 | 2015-04-09 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
PT3119397T (en) | 2014-03-19 | 2022-04-11 | Infinity Pharmaceuticals Inc | Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders |
US9708348B2 (en) | 2014-10-03 | 2017-07-18 | Infinity Pharmaceuticals, Inc. | Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof |
US10160761B2 (en) | 2015-09-14 | 2018-12-25 | Infinity Pharmaceuticals, Inc. | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same |
WO2017161116A1 (en) | 2016-03-17 | 2017-09-21 | Infinity Pharmaceuticals, Inc. | Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors |
US10919914B2 (en) | 2016-06-08 | 2021-02-16 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
WO2018112843A1 (en) | 2016-12-22 | 2018-06-28 | Merck Sharp & Dohme Corp. | Heteroaryl piperidine ether allosteric modulators of the m4 muscarinic acetylcholine receptor |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
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US3133056A (en) * | 1961-05-15 | 1964-05-12 | May & Baker Ltd | N-phenylpiperazine derivatives of tetrahydrobenzodiazepines |
US3984398A (en) | 1966-12-14 | 1976-10-05 | Roussel-Uclaf | 1,5-Benzodiazepine-2,4-diones |
US4001408A (en) | 1966-12-14 | 1977-01-04 | Roussel-Uclaf | Substituted heterocyclic compounds, processes and composition including those |
BE707667A (en) | 1966-12-14 | 1968-06-07 | ||
GB1460936A (en) | 1974-10-01 | 1977-01-06 | Beecham Group Ltd | Benzodiazepines |
JPS545981A (en) * | 1977-06-10 | 1979-01-17 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivatives |
NZ187452A (en) * | 1977-06-10 | 1980-05-27 | Otsuka Pharma Co Ltd | N- substituted-aminocarbonylpropoxy-carbostyrils and their preparation |
JPS54163825A (en) * | 1978-06-15 | 1979-12-26 | Otsuka Pharma Co Ltd | Phosphoesterase inhibitor |
JPS5579372A (en) * | 1978-12-08 | 1980-06-14 | Otsuka Pharmaceut Co Ltd | Preparation of carbostyril derivative |
JPS56122356A (en) | 1980-02-29 | 1981-09-25 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
JPS5780322A (en) * | 1980-11-05 | 1982-05-19 | Otsuka Pharmaceut Co Ltd | Cardiotonic agent |
JPS6010008B2 (en) * | 1982-07-12 | 1985-03-14 | 大塚製薬株式会社 | Platelet aggregation inhibitor |
JP2753622B2 (en) * | 1988-05-02 | 1998-05-20 | 大塚製薬株式会社 | Carbostyril derivative |
DK391189A (en) * | 1988-08-10 | 1990-02-11 | Otsuka Pharma Co Ltd | carbostyril derivatives |
JPH0296133A (en) | 1988-10-01 | 1990-04-06 | Fuji Photo Film Co Ltd | Silver halide color photographic sensitive material |
JPH03148223A (en) * | 1989-11-02 | 1991-06-25 | Otsuka Pharmaceut Co Ltd | Inhibitor of blood platelet aggregation |
BR9200951A (en) * | 1991-03-21 | 1992-11-17 | Hoffmann La Roche | COMPOUNDS, PROCESS FOR ITS PRODUCTION, PHARMACEUTICAL PREPARATIONS AND USE |
JPH05194405A (en) * | 1991-08-23 | 1993-08-03 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative and platelet aggregation suppressing agent |
CA2093633A1 (en) * | 1991-08-23 | 1993-02-24 | Seiji Sato | Carbostyril derivative and platelets aggregation inhibitory agent |
PE27497A1 (en) | 1994-04-15 | 1997-08-07 | Glaxo Inc | DERIVATIVES OF 1,5 BENZODIAZEPINA |
US5700797A (en) | 1995-06-07 | 1997-12-23 | Merck & Co, Inc. | N-(2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)-3-amides |
US5691331A (en) | 1995-06-07 | 1997-11-25 | Merck & Co., Inc. | N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides |
TW338037B (en) | 1995-10-05 | 1998-08-11 | Otsuka Pharma Co Ltd | Carbostyril derivatives possessing platelet aggregation inhibitory activity, antithrombotic activity, intima thinkening, inhibitory activity and phosphoriesterase inhibitory activity, their preparation and pharmaceutical composition |
JP2964029B2 (en) * | 1995-10-05 | 1999-10-18 | 大塚製薬株式会社 | Carbostyril derivative |
GB0008179D0 (en) | 2000-04-05 | 2000-05-24 | Glaxo Group Ltd | Chemical process |
WO2001010216A1 (en) | 1999-08-09 | 2001-02-15 | Merck & Co., Inc. | Antiarrhythmic compounds |
US6949542B2 (en) | 2002-02-06 | 2005-09-27 | Hoffman-La Roche Inc. | Dihydro-benzo[b][1,4]diazepin-2-one derivatives |
US7772433B2 (en) | 2002-02-28 | 2010-08-10 | University Of Tennessee Research Foundation | SARMS and method of use thereof |
EA011087B1 (en) * | 2002-12-20 | 2008-12-30 | Эмджен Инк. | Compounds and pharmaceutical compositions for treating inflammation diseases |
AR055203A1 (en) | 2005-08-31 | 2007-08-08 | Otsuka Pharma Co Ltd | BENZOTIOPHENE DERIVATIVES WITH ANTIPSYTICAL PROPERTIES |
JP2007290984A (en) * | 2006-04-21 | 2007-11-08 | Kowa Co | Cofilin binder and anticancer agent having cofilin binder as active ingredient |
JP4785881B2 (en) | 2007-02-27 | 2011-10-05 | 大塚製薬株式会社 | Medicine |
PT2254873E (en) * | 2008-02-22 | 2014-08-29 | Otsuka Pharma Co Ltd | Benzodiazepine compound and pharmaceutical composition |
-
2010
- 2010-08-19 TW TW099127738A patent/TWI481601B/en active
- 2010-08-20 PL PL10751720T patent/PL2467364T3/en unknown
- 2010-08-20 US US13/388,442 patent/US8822453B2/en not_active Expired - Fee Related
- 2010-08-20 RU RU2012110553/04A patent/RU2012110553A/en unknown
- 2010-08-20 KR KR1020127004471A patent/KR20120081973A/en not_active Application Discontinuation
- 2010-08-20 WO PCT/JP2010/064545 patent/WO2011021726A2/en active Application Filing
- 2010-08-20 MX MX2012002149A patent/MX2012002149A/en active IP Right Grant
- 2010-08-20 DK DK10751720.3T patent/DK2467364T3/en active
- 2010-08-20 AR ARP100103052A patent/AR078098A1/en unknown
- 2010-08-20 PT PT107517203T patent/PT2467364E/en unknown
- 2010-08-20 EP EP20140153417 patent/EP2727917A1/en not_active Withdrawn
- 2010-08-20 EP EP14153418.0A patent/EP2746272A1/en not_active Withdrawn
- 2010-08-20 SG SG2011095098A patent/SG177316A1/en unknown
- 2010-08-20 CN CN201080037286.0A patent/CN102482234B/en not_active Expired - Fee Related
- 2010-08-20 ES ES10751720.3T patent/ES2477221T3/en active Active
- 2010-08-20 EP EP10751720.3A patent/EP2467364B9/en not_active Not-in-force
- 2010-08-20 SI SI201030598T patent/SI2467364T1/en unknown
- 2010-08-20 NZ NZ598918A patent/NZ598918A/en not_active IP Right Cessation
- 2010-08-20 CA CA2771579A patent/CA2771579A1/en not_active Abandoned
- 2010-08-20 AU AU2010285621A patent/AU2010285621A1/en not_active Abandoned
- 2010-08-20 IN IN1985DEN2012 patent/IN2012DN01985A/en unknown
- 2010-08-20 JP JP2012508284A patent/JP5769700B2/en not_active Expired - Fee Related
-
2011
- 2011-12-20 IL IL217101A patent/IL217101A0/en unknown
-
2012
- 2012-02-13 ZA ZA2012/01025A patent/ZA201201025B/en unknown
- 2012-03-20 CO CO12046744A patent/CO6440511A2/en active IP Right Grant
- 2012-08-15 HK HK12108042.7A patent/HK1167391A1/en not_active IP Right Cessation
-
2014
- 2014-06-25 US US14/314,142 patent/US20140343277A1/en not_active Abandoned
- 2014-06-25 US US14/314,189 patent/US9212187B2/en not_active Expired - Fee Related
- 2014-07-04 HR HRP20140636AT patent/HRP20140636T1/en unknown
-
2015
- 2015-06-08 JP JP2015115391A patent/JP2015199748A/en active Pending
-
2016
- 2016-08-03 IL IL247086A patent/IL247086A0/en unknown
- 2016-08-08 AU AU2016210778A patent/AU2016210778A1/en not_active Abandoned
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