IN186880B - - Google Patents
Info
- Publication number
- IN186880B IN186880B IN3102DE1997A IN186880B IN 186880 B IN186880 B IN 186880B IN 3102DE1997 A IN3102DE1997 A IN 3102DE1997A IN 186880 B IN186880 B IN 186880B
- Authority
- IN
- India
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN3102DE1997 IN186880B (de) | 1997-10-28 | 1997-10-28 | |
US09/064,285 US5917058A (en) | 1997-10-28 | 1998-04-22 | Process of lactonization in the preparation of statins |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN3102DE1997 IN186880B (de) | 1997-10-28 | 1997-10-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN186880B true IN186880B (de) | 2001-12-01 |
Family
ID=11092798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN3102DE1997 IN186880B (de) | 1997-10-28 | 1997-10-28 |
Country Status (2)
Country | Link |
---|---|
US (1) | US5917058A (de) |
IN (1) | IN186880B (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2127500A (en) | 1999-11-11 | 2001-06-06 | Biocon India Limited | Process for manufacturing simvastatin and the novel intermediates |
US6573385B1 (en) | 1999-11-11 | 2003-06-03 | Biocon India Limited | Process for manufacturing simvastatin and novel intermediates thereof |
US6521762B2 (en) | 2000-03-03 | 2003-02-18 | BIOGAL Gyógyszergyar RT. | Process for purifying lovastatin and simvastatin with reduced levels of dimeric impurities |
NL1017548C2 (nl) | 2001-03-09 | 2002-09-10 | Synthon Bv | Een lactonisatie proces. |
US6797831B2 (en) * | 2001-05-18 | 2004-09-28 | Aurobindo Pharma Limited | Process for lactonization to produce simvastatin |
SK692003A3 (en) * | 2001-05-18 | 2003-12-02 | Aurobindo Pharma Ltd | A process for lactonization to produce highly pure simvastatin |
KR100407758B1 (ko) * | 2001-08-27 | 2003-12-01 | 씨제이 주식회사 | 스타틴의 제조에 있어서 락톤화 방법 |
KR100423892B1 (ko) * | 2001-12-03 | 2004-03-22 | 씨제이 주식회사 | 스타틴의 제조에 있어서 새로운 락톤화 방법 |
KR100502834B1 (ko) * | 2002-03-25 | 2005-07-20 | 보령제약 주식회사 | 개선된 락톤화 반응에 의한 심바스타틴의 제조방법 및이의 정제방법 |
KR100502833B1 (ko) * | 2002-03-25 | 2005-07-25 | 보령제약 주식회사 | 심바스타틴 및 이의 중간체 화합물들의 개선된 제조방법 |
US6603022B1 (en) | 2002-05-10 | 2003-08-05 | Biocon India Limited | Process for manufacturing Simvastatin and novel intermediates thereof |
US7777056B2 (en) * | 2004-03-30 | 2010-08-17 | Lupin Ltd. | Method for manufacture of 4-hydroxy pyran-2-one derivatives |
US20050239885A1 (en) * | 2004-04-22 | 2005-10-27 | Glenmark Pharmaceuticals Limited | Processes for the preparation of simvastatin |
AU2004323102A1 (en) * | 2004-09-08 | 2006-03-16 | Jubilant Organosys Limited | An improved process for lactonization in the preparation of statins |
WO2006059346A2 (en) * | 2004-12-01 | 2006-06-08 | Morepen Laboratories Limited | An improved process for lactonization to produce highly pure statins |
WO2007020079A2 (en) * | 2005-08-17 | 2007-02-22 | Synthon B.V. | Orally disintegratable simvastatin tablets |
US20090048335A1 (en) * | 2007-08-17 | 2009-02-19 | Venkata Naga Mandava | Process for preparing simvastatin |
EP3190123B1 (de) | 2009-09-30 | 2019-07-24 | Codexis, Inc. | Verbesserte durch lov-d-acyltransferase vermittelte acylierung |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4820850A (en) * | 1987-07-10 | 1989-04-11 | Merck & Co., Inc. | Process for α-C-alkylation of the 8-acyl group on mevinolin and analogs thereof |
US4916239A (en) * | 1988-07-19 | 1990-04-10 | Merck & Co., Inc. | Process for the lactonization of mevinic acids and analogs thereof |
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1997
- 1997-10-28 IN IN3102DE1997 patent/IN186880B/en unknown
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1998
- 1998-04-22 US US09/064,285 patent/US5917058A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5917058A (en) | 1999-06-29 |