IL99468A - (3s, 4s)-delta- 6-tetrahydrocannabinol- 7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them - Google Patents
(3s, 4s)-delta- 6-tetrahydrocannabinol- 7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL99468A IL99468A IL99468A IL9946891A IL99468A IL 99468 A IL99468 A IL 99468A IL 99468 A IL99468 A IL 99468A IL 9946891 A IL9946891 A IL 9946891A IL 99468 A IL99468 A IL 99468A
- Authority
- IL
- Israel
- Prior art keywords
- group
- preparation
- pharmaceutical compositions
- formula
- alkyl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL99468A IL99468A (en) | 1991-09-12 | 1991-09-12 | (3s, 4s)-delta- 6-tetrahydrocannabinol- 7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them |
AT92920778T ATE187721T1 (de) | 1991-09-12 | 1992-09-11 | (3s, 4s)-delta-6-tetrahydrocannabinol-7-säuren und ihre derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen |
EP92920778A EP0642504B1 (de) | 1991-09-12 | 1992-09-11 | (3s, 4s)-delta-6-tetrahydrocannabinol-7-säuren und ihre derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen |
CA002118929A CA2118929C (en) | 1991-09-12 | 1992-09-11 | (3s,4s)-delta-6-tetrahydrocannabinol-7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them |
JP50551793A JP3298881B2 (ja) | 1991-09-12 | 1992-09-11 | (3s,4s)−デルタ−6−テトラヒドロカンナビノール−7−酸及びそれらの誘導体並びにそれらの合成方法並びにそれらを含む医薬組成物 |
PCT/US1992/007718 WO1993005031A1 (en) | 1991-09-12 | 1992-09-11 | (3s,4s)-delta-6-tetrahydrocannabinol-7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them |
US08/190,089 US5635530A (en) | 1991-09-12 | 1992-09-11 | (3S,4S)-delta-6-tetrahydrocannabinol-7-oic acids and derivatives thereof, processors for their preparation and pharmaceutical compositions containing them |
AU26787/92A AU664204B2 (en) | 1991-09-12 | 1992-09-11 | (3S,4S)-delta-6-tetrahydrocannabinol-7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them |
DE69230446T DE69230446T2 (de) | 1991-09-12 | 1992-09-11 | (3s, 4s)-delta-6-tetrahydrocannabinol-7-säuren und ihre derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen |
US08/192,923 US5538993A (en) | 1991-09-12 | 1994-02-07 | Certain tetrahydrocannabinol-7-oic acid derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL99468A IL99468A (en) | 1991-09-12 | 1991-09-12 | (3s, 4s)-delta- 6-tetrahydrocannabinol- 7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them |
Publications (2)
Publication Number | Publication Date |
---|---|
IL99468A0 IL99468A0 (en) | 1992-08-18 |
IL99468A true IL99468A (en) | 1997-09-30 |
Family
ID=11062883
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL99468A IL99468A (en) | 1991-09-12 | 1991-09-12 | (3s, 4s)-delta- 6-tetrahydrocannabinol- 7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0642504B1 (de) |
JP (1) | JP3298881B2 (de) |
AT (1) | ATE187721T1 (de) |
AU (1) | AU664204B2 (de) |
CA (1) | CA2118929C (de) |
DE (1) | DE69230446T2 (de) |
IL (1) | IL99468A (de) |
WO (1) | WO1993005031A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5338753A (en) * | 1992-07-14 | 1994-08-16 | Sumner H. Burstein | (3R,4R)-Δ6 -tetrahydrocannabinol-7-oic acids useful as antiinflammatory agents and analgesics |
DE19706903A1 (de) * | 1997-02-21 | 1998-08-27 | Bayer Ag | Verwendung von bekannten Agonisten des zentralen Cannabinoid-Rezeptors CB 1 |
US6162829A (en) * | 1997-10-17 | 2000-12-19 | Atlantic Pharmaceuticals, Inc. | (3R,4R)-Δ8 -tetrahydrocannabinol-11-oic acids useful as antiinflammatory agents and analgesics |
JP2002512188A (ja) | 1998-04-21 | 2002-04-23 | ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ, アズ レプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 抗酸化剤及び神経保護剤としてのカンナビノイド類 |
WO2003006010A1 (en) * | 2001-07-10 | 2003-01-23 | Norton Healthcare Limited | Aerosol formulations of δ8 tetrahydrocannabinol |
WO2003063847A1 (en) * | 2002-02-01 | 2003-08-07 | Gw Pharma Limited | Compositions comprising cannabinoids for treatment of nausea, vomiting, emesis, motion sickness or like conditions |
GB0202385D0 (en) * | 2002-02-01 | 2002-03-20 | Gw Pharma Ltd | Compositions for the treatment of nausea,vomiting,emesis,motion sicknes or like conditions |
IL148244A0 (en) | 2002-02-19 | 2002-09-12 | Yissum Res Dev Co | Anti-nausea and anti-vomiting activity of cannabidiol compounds |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4833073A (en) * | 1987-01-27 | 1989-05-23 | Hoffmann-La Roche Inc. | Immunoassay for tetrahydrocannabinol metabolites |
US5144030A (en) * | 1987-02-17 | 1992-09-01 | Abbott Laboratories | Fluorescene polarization immunoassay for tetrahydrocannabinoids |
US4973603A (en) * | 1988-06-16 | 1990-11-27 | Sumner Burstein | Platelet activating factor antagonist and methods of use therefor |
US5036014A (en) * | 1989-01-31 | 1991-07-30 | Elsohly Mahmoud A | Deuterated cannabinoids as standards for the analysis of tetrahydrocannabinol and its metabolites in biological fluids |
-
1991
- 1991-09-12 IL IL99468A patent/IL99468A/xx not_active IP Right Cessation
-
1992
- 1992-09-11 EP EP92920778A patent/EP0642504B1/de not_active Expired - Lifetime
- 1992-09-11 JP JP50551793A patent/JP3298881B2/ja not_active Expired - Fee Related
- 1992-09-11 AT AT92920778T patent/ATE187721T1/de not_active IP Right Cessation
- 1992-09-11 DE DE69230446T patent/DE69230446T2/de not_active Expired - Fee Related
- 1992-09-11 AU AU26787/92A patent/AU664204B2/en not_active Ceased
- 1992-09-11 WO PCT/US1992/007718 patent/WO1993005031A1/en active IP Right Grant
- 1992-09-11 CA CA002118929A patent/CA2118929C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0642504A4 (de) | 1994-08-22 |
AU2678792A (en) | 1993-04-05 |
WO1993005031A1 (en) | 1993-03-18 |
DE69230446D1 (de) | 2000-01-20 |
EP0642504A1 (de) | 1995-03-15 |
JPH07505119A (ja) | 1995-06-08 |
JP3298881B2 (ja) | 2002-07-08 |
ATE187721T1 (de) | 2000-01-15 |
CA2118929A1 (en) | 1993-03-18 |
EP0642504B1 (de) | 1999-12-15 |
IL99468A0 (en) | 1992-08-18 |
DE69230446T2 (de) | 2000-04-13 |
AU664204B2 (en) | 1995-11-09 |
CA2118929C (en) | 2004-04-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |