IL98164A0 - Antiviral nucleoside derivatives,process for their preparation and pharmaceutical compositions containing them - Google Patents
Antiviral nucleoside derivatives,process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL98164A0 IL98164A0 IL98164A IL9816491A IL98164A0 IL 98164 A0 IL98164 A0 IL 98164A0 IL 98164 A IL98164 A IL 98164A IL 9816491 A IL9816491 A IL 9816491A IL 98164 A0 IL98164 A0 IL 98164A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- nucleoside derivatives
- antiviral nucleoside
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52477390A | 1990-05-17 | 1990-05-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL98164A0 true IL98164A0 (en) | 1992-06-21 |
Family
ID=24090612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL98164A IL98164A0 (en) | 1990-05-17 | 1991-05-16 | Antiviral nucleoside derivatives,process for their preparation and pharmaceutical compositions containing them |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0457326A1 (de) |
| JP (1) | JPH04226999A (de) |
| KR (1) | KR910020027A (de) |
| AU (1) | AU7623991A (de) |
| CA (1) | CA2042795A1 (de) |
| FI (1) | FI912376A7 (de) |
| IE (1) | IE911673A1 (de) |
| IL (1) | IL98164A0 (de) |
| NO (1) | NO911936L (de) |
| NZ (1) | NZ238166A (de) |
| ZA (1) | ZA913721B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2504078C (en) * | 1991-07-05 | 2007-08-28 | Wellstat Therapeutics Corporation | Treatment of chemotherapeutic agent and antiviral agent toxicity with acylated pyrimidine nucleosides |
| US5446137B1 (en) * | 1993-12-09 | 1998-10-06 | Behringwerke Ag | Oligonucleotides containing 4'-substituted nucleotides |
| JP2002322192A (ja) * | 2000-08-10 | 2002-11-08 | Sankyo Co Ltd | ２’−ｏ，４’−ｃ−架橋ヌクレオシドトリリン酸体 |
| CN101862345B (zh) | 2000-10-18 | 2014-06-04 | 吉利德制药有限责任公司 | 用于治疗病毒感染和异常细胞增殖的修饰核苷类化合物 |
| GB0114286D0 (en) | 2001-06-12 | 2001-08-01 | Hoffmann La Roche | Nucleoside Derivatives |
| TWI294882B (en) * | 2002-12-09 | 2008-03-21 | Hoffmann La Roche | Anhydrous crystalline azido cytosine hemisulfate derivative |
| WO2004062676A1 (en) * | 2003-01-09 | 2004-07-29 | F. Hoffmann-La Roche Ag | -modified nucleoside derivatives for treating flaviviridae infections |
| WO2005003147A2 (en) | 2003-05-30 | 2005-01-13 | Pharmasset, Inc. | Modified fluorinated nucleoside analogues |
| CN101023094B (zh) | 2004-07-21 | 2011-05-18 | 法莫赛特股份有限公司 | 烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备 |
| MX2007003085A (es) | 2004-09-14 | 2007-08-02 | Pharmasset Inc | Preparacion de 2'-fluoro-2'-alquilo sustituido u otras ribofuranosil pirimidinas y purinas opcionalmente sustituidas y sus derivados. |
| NZ597544A (en) * | 2005-09-26 | 2013-04-26 | Gilead Pharmasset Llc | Modified 4'-nucleosides as antiviral agents |
| CN101573370B (zh) * | 2006-10-10 | 2013-09-11 | 美迪维尔公司 | Hcv核苷类抑制剂 |
| AU2011305652B2 (en) | 2010-09-22 | 2016-10-20 | Janssen Biopharma, Inc. | Azido nucleosides and nucleotide analogs |
| EP2794627B1 (de) * | 2011-12-22 | 2018-09-26 | Alios Biopharma, Inc. | Substituierte nukleoside, nukleotide und analoga davon |
| US9441007B2 (en) | 2012-03-21 | 2016-09-13 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| USRE48171E1 (en) | 2012-03-21 | 2020-08-25 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| CN110540555B (zh) * | 2018-05-28 | 2023-01-24 | 江苏恒瑞医药股份有限公司 | 一种游离核苷磷酸的方法 |
| CN109893536B (zh) * | 2018-07-02 | 2021-04-27 | 河南真实生物科技有限公司 | 4’-取代核苷的晶型、制备和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3910885A (en) * | 1974-03-12 | 1975-10-07 | Syntex Inc | 4-Alkoxy nucleosides and intermediates therefore |
| DK582489A (da) * | 1988-11-21 | 1990-05-22 | Syntex Inc | Substituerede 2'-deoxy-4'-azido-nucleosider, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende samme |
-
1991
- 1991-04-29 AU AU76239/91A patent/AU7623991A/en not_active Abandoned
- 1991-05-16 EP EP91107964A patent/EP0457326A1/de not_active Withdrawn
- 1991-05-16 KR KR1019910007917A patent/KR910020027A/ko not_active Withdrawn
- 1991-05-16 NO NO91911936A patent/NO911936L/no unknown
- 1991-05-16 FI FI912376A patent/FI912376A7/fi not_active Application Discontinuation
- 1991-05-16 IL IL98164A patent/IL98164A0/xx unknown
- 1991-05-16 ZA ZA913721A patent/ZA913721B/xx unknown
- 1991-05-16 IE IE167391A patent/IE911673A1/en unknown
- 1991-05-16 NZ NZ238166A patent/NZ238166A/xx unknown
- 1991-05-16 JP JP3141210A patent/JPH04226999A/ja active Pending
- 1991-05-16 CA CA002042795A patent/CA2042795A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0457326A1 (de) | 1991-11-21 |
| AU7623991A (en) | 1991-11-21 |
| JPH04226999A (ja) | 1992-08-17 |
| FI912376A7 (fi) | 1991-11-18 |
| NO911936L (no) | 1991-11-18 |
| CA2042795A1 (en) | 1991-11-18 |
| NO911936D0 (no) | 1991-05-16 |
| NZ238166A (en) | 1993-09-27 |
| KR910020027A (ko) | 1991-12-19 |
| FI912376A0 (fi) | 1991-05-16 |
| ZA913721B (en) | 1992-02-26 |
| IE911673A1 (en) | 1991-11-20 |
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