IL94980A - תולדות פנטאפפטיד נגד הרפז, בעלות שרשרת צדדית של חומצה אספרטית מותמרת, הכנתן ותכשירי רוקחות המכילים אותן - Google Patents

תולדות פנטאפפטיד נגד הרפז, בעלות שרשרת צדדית של חומצה אספרטית מותמרת, הכנתן ותכשירי רוקחות המכילים אותן

Info

Publication number
IL94980A
IL94980A IL9498090A IL9498090A IL94980A IL 94980 A IL94980 A IL 94980A IL 9498090 A IL9498090 A IL 9498090A IL 9498090 A IL9498090 A IL 9498090A IL 94980 A IL94980 A IL 94980A
Authority
IL
Israel
Prior art keywords
asp
alkyl
val
hydrogen
phenyl
Prior art date
Application number
IL9498090A
Other languages
English (en)
Other versions
IL94980A0 (en
Original Assignee
Bio Mega Boehringer Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA000605091A external-priority patent/CA1340683C/en
Priority claimed from CA002019005A external-priority patent/CA2019005C/en
Application filed by Bio Mega Boehringer Ingelheim filed Critical Bio Mega Boehringer Ingelheim
Publication of IL94980A0 publication Critical patent/IL94980A0/xx
Publication of IL94980A publication Critical patent/IL94980A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
IL9498090A 1989-07-07 1990-07-05 תולדות פנטאפפטיד נגד הרפז, בעלות שרשרת צדדית של חומצה אספרטית מותמרת, הכנתן ותכשירי רוקחות המכילים אותן IL94980A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA000605091A CA1340683C (en) 1989-07-07 1989-07-07 Antiherpes pentapeptides having a substituted aspartic acid side chain
CA002019005A CA2019005C (en) 1990-06-14 1990-06-14 Antiherpes pentapeptide derivatives having a cycloalkyl substituted aspartic acid side chain

Publications (2)

Publication Number Publication Date
IL94980A0 IL94980A0 (en) 1991-06-10
IL94980A true IL94980A (he) 1995-03-15

Family

ID=25672870

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9498090A IL94980A (he) 1989-07-07 1990-07-05 תולדות פנטאפפטיד נגד הרפז, בעלות שרשרת צדדית של חומצה אספרטית מותמרת, הכנתן ותכשירי רוקחות המכילים אותן

Country Status (6)

Country Link
EP (1) EP0411334B1 (he)
JP (1) JP2877909B2 (he)
AT (1) ATE118785T1 (he)
DE (1) DE69017113T2 (he)
IL (1) IL94980A (he)
NZ (1) NZ234376A (he)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69320390T2 (de) 1992-03-12 1999-02-11 Boehringer Ingelheim (Canada) Ltd., Laval, Quebec Isosterische Peptidderivate gegen Herpes
US5830864A (en) * 1992-03-12 1998-11-03 Boehringer Ingelheim (Canada), Ltd. Antiherpes peptide derivatives having a ureido n-terminus
US5846941A (en) * 1992-03-12 1998-12-08 Boehringer Ingelheim (Canada) Ltd. Isosteric antiherpes peptide derivatives II
ES2152269T3 (es) * 1993-03-03 2001-02-01 Boehringer Ingelheim Ca Ltd Inhibidores de ribonucleotido-reductasa de herpesvirus.
CA2152541C (en) * 1995-06-23 1998-12-15 Boehringer Ingelheim (Canada) Ltd./ Boehringer Ingelheim (Canada) Ltee Herpes ribonucleotide reductase inhibitors
US5948935A (en) * 1997-01-23 1999-09-07 Boehringer Ingelheim (Canada) Ltd. Process and intermediates for (s)-α-amino-1-carboxycyclopentaneacetic acid
JP5828217B2 (ja) 2011-04-15 2015-12-02 三菱マテリアル株式会社 ドリル

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795740A (en) * 1986-05-20 1989-01-03 Cohen Eric A Antiviral peptides and means for treating herpes infections
EP0292255A3 (en) * 1987-05-22 1990-08-22 Merck & Co. Inc. Inhibitor of ribonucleotide reductase

Also Published As

Publication number Publication date
EP0411334A1 (en) 1991-02-06
DE69017113D1 (de) 1995-03-30
DE69017113T2 (de) 1995-08-03
JPH03215497A (ja) 1991-09-20
NZ234376A (en) 1997-05-26
JP2877909B2 (ja) 1999-04-05
IL94980A0 (en) 1991-06-10
EP0411334B1 (en) 1995-02-22
ATE118785T1 (de) 1995-03-15

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