IL87600A0 - Hmg-coa reductase inhibitors,their preparation and pharmaceutical compositions containing them - Google Patents
Hmg-coa reductase inhibitors,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL87600A0 IL87600A0 IL87600A IL8760088A IL87600A0 IL 87600 A0 IL87600 A0 IL 87600A0 IL 87600 A IL87600 A IL 87600A IL 8760088 A IL8760088 A IL 8760088A IL 87600 A0 IL87600 A0 IL 87600A0
- Authority
- IL
- Israel
- Prior art keywords
- hmg
- preparation
- pharmaceutical compositions
- compositions containing
- coa reductase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9235487A | 1987-09-02 | 1987-09-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL87600A0 true IL87600A0 (en) | 1989-01-31 |
Family
ID=22232825
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL87600A IL87600A0 (en) | 1987-09-02 | 1988-08-30 | Hmg-coa reductase inhibitors,their preparation and pharmaceutical compositions containing them |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0306264A3 (ja) |
JP (1) | JPH0196152A (ja) |
KR (1) | KR890005080A (ja) |
AU (1) | AU606203B2 (ja) |
DK (1) | DK485888A (ja) |
IL (1) | IL87600A0 (ja) |
PT (1) | PT88364A (ja) |
ZA (1) | ZA886468B (ja) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI893004A (fi) * | 1988-06-29 | 1989-12-30 | Merck & Co Inc | 5-oxygenerade hmg-coa-reduktas -inhibitorer. |
US5073568A (en) * | 1988-11-14 | 1991-12-17 | Hoffmann-La Roche Inc. | Antipsoriatic agents |
US5001148A (en) * | 1989-06-07 | 1991-03-19 | E. R. Squibb & Sons, Inc. | Mevinic acid derivatives |
EP0415488B1 (en) * | 1989-08-31 | 1994-04-20 | Merck & Co. Inc. | 7-Substituted HMG-COA reductase inhibitors |
US5025017A (en) * | 1989-09-28 | 1991-06-18 | E. R. Squibb & Sons, Inc. | Seco-mevinic acid derivatives useful as antihypercholesterolemic agents and new intermediates |
GB9007738D0 (en) * | 1990-04-05 | 1990-06-06 | British Bio Technology | Compounds |
TW227552B (ja) * | 1990-07-06 | 1994-08-01 | Squibb & Sons Inc | |
US5159104A (en) * | 1991-05-01 | 1992-10-27 | Merck & Co., Inc. | Process to simvastatin ester |
US8877221B2 (en) | 2010-10-27 | 2014-11-04 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising calcium phosphate particles and statins and methods of using the same |
US9107983B2 (en) | 2010-10-27 | 2015-08-18 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising statins |
US9308190B2 (en) | 2011-06-06 | 2016-04-12 | Warsaw Orthopedic, Inc. | Methods and compositions to enhance bone growth comprising a statin |
EP3698797A1 (en) | 2017-10-16 | 2020-08-26 | Tsinghua University | Mevalonic acid pathway inhibitor and pharmaceutical composition thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4294846A (en) * | 1979-09-21 | 1981-10-13 | Merck & Co., Inc. | Hypocholesteremic fermentation products and products of preparation |
EP0204287A3 (en) * | 1985-06-04 | 1987-07-01 | Merck & Co. Inc. | Process for the preparation of hmg-coa reductase inhibitors with a 3,5-dihydroxypentanoate subunit |
US4668699A (en) * | 1985-08-05 | 1987-05-26 | Merck & Co., Inc. | Novel HMG-CoA reductase inhibitors |
PT85109A (en) * | 1986-06-23 | 1987-07-01 | Merck & Co Inc | Process for the preparation of hydroxy-tetrahydropyranone derivatives or corresponding ring opened dihydroxy acids which are hmg-coa reductase inhibitors |
FI893004A (fi) * | 1988-06-29 | 1989-12-30 | Merck & Co Inc | 5-oxygenerade hmg-coa-reduktas -inhibitorer. |
-
1988
- 1988-08-29 PT PT88364A patent/PT88364A/pt not_active Application Discontinuation
- 1988-08-30 EP EP88308011A patent/EP0306264A3/en not_active Withdrawn
- 1988-08-30 IL IL87600A patent/IL87600A0/xx unknown
- 1988-08-31 ZA ZA886468A patent/ZA886468B/xx unknown
- 1988-09-01 KR KR1019880011278A patent/KR890005080A/ko not_active Application Discontinuation
- 1988-09-01 AU AU21750/88A patent/AU606203B2/en not_active Expired - Fee Related
- 1988-09-01 DK DK485888A patent/DK485888A/da not_active Application Discontinuation
- 1988-09-02 JP JP63218653A patent/JPH0196152A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
PT88364A (pt) | 1989-07-31 |
AU2175088A (en) | 1989-03-16 |
EP0306264A2 (en) | 1989-03-08 |
DK485888D0 (da) | 1988-09-01 |
DK485888A (da) | 1989-03-03 |
JPH0196152A (ja) | 1989-04-14 |
EP0306264A3 (en) | 1989-08-16 |
KR890005080A (ko) | 1989-05-11 |
AU606203B2 (en) | 1991-01-31 |
ZA886468B (en) | 1989-04-26 |
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