IL86930A - Preparation of(1r(1alpha(z),2beta,3beta,5alpha))-(+)-7-(5-(1,1'-biphenyl)-4-yl methoxy-3-hydroxy-2-(1-piperidinyl)cyclopentyl-4-heptenoic acid and novel intermediates thereof - Google Patents

Preparation of(1r(1alpha(z),2beta,3beta,5alpha))-(+)-7-(5-(1,1'-biphenyl)-4-yl methoxy-3-hydroxy-2-(1-piperidinyl)cyclopentyl-4-heptenoic acid and novel intermediates thereof

Info

Publication number
IL86930A
IL86930A IL86930A IL8693088A IL86930A IL 86930 A IL86930 A IL 86930A IL 86930 A IL86930 A IL 86930A IL 8693088 A IL8693088 A IL 8693088A IL 86930 A IL86930 A IL 86930A
Authority
IL
Israel
Prior art keywords
2beta
5alpha
3beta
1alpha
piperidinyl
Prior art date
Application number
IL86930A
Other languages
English (en)
Other versions
IL86930A0 (en
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IL86930A0 publication Critical patent/IL86930A0/xx
Publication of IL86930A publication Critical patent/IL86930A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL86930A 1987-06-30 1988-06-30 Preparation of(1r(1alpha(z),2beta,3beta,5alpha))-(+)-7-(5-(1,1'-biphenyl)-4-yl methoxy-3-hydroxy-2-(1-piperidinyl)cyclopentyl-4-heptenoic acid and novel intermediates thereof IL86930A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878715333A GB8715333D0 (en) 1987-06-30 1987-06-30 Process

Publications (2)

Publication Number Publication Date
IL86930A0 IL86930A0 (en) 1988-11-30
IL86930A true IL86930A (en) 1992-07-15

Family

ID=10619818

Family Applications (2)

Application Number Title Priority Date Filing Date
IL86548A IL86548A0 (en) 1987-06-30 1988-05-30 Preparation of piperidinylcyclopentylheptenoic acid derivatives
IL86930A IL86930A (en) 1987-06-30 1988-06-30 Preparation of(1r(1alpha(z),2beta,3beta,5alpha))-(+)-7-(5-(1,1'-biphenyl)-4-yl methoxy-3-hydroxy-2-(1-piperidinyl)cyclopentyl-4-heptenoic acid and novel intermediates thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL86548A IL86548A0 (en) 1987-06-30 1988-05-30 Preparation of piperidinylcyclopentylheptenoic acid derivatives

Country Status (15)

Country Link
US (1) US4933461A (xx)
EP (1) EP0297853A1 (xx)
JP (1) JPS6422864A (xx)
KR (1) KR890000425A (xx)
AU (1) AU615922B2 (xx)
CA (1) CA1312609C (xx)
DK (1) DK357388A (xx)
FI (1) FI883105A (xx)
GB (1) GB8715333D0 (xx)
IL (2) IL86548A0 (xx)
NO (1) NO882883L (xx)
NZ (1) NZ225221A (xx)
PH (1) PH24774A (xx)
PT (1) PT87861B (xx)
ZA (1) ZA884649B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE509731C2 (sv) * 1996-05-14 1999-03-01 Labwell Ab Metod för palladium-katalyserade organiska reaktioner innefattande ett uppvärmningssteg utfört med mikrovågsenergi
ZA974582B (en) * 1996-06-03 1998-11-26 American Cyanamid Co Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds
US5892131A (en) * 1997-05-29 1999-04-06 American Cyanamid Company Process for the preparation of pesticidal fluoroolefin compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU542949B2 (en) * 1980-01-09 1985-03-28 Glaxo Group Limited Prostanoid compounds
JPS5718671A (en) * 1980-04-30 1982-01-30 Glaxo Group Ltd Aminocyclopentane alkenoic acid and esters thereof,manufacture and drug composition
JPS57183772A (en) * 1981-04-29 1982-11-12 Glaxo Group Ltd Aminocyclopentanol acids and esters, manufacture and medicinal composition
GB2127406B (en) * 1982-09-16 1986-03-05 Glaxo Group Ltd Piperidinlycyclopentanolheptenoic acid salt
ZA838018B (en) * 1982-10-28 1984-06-27 Glaxo Group Ltd Preparation of aminocyclopentane acids
GB8601985D0 (en) * 1986-01-28 1986-03-05 Glaxo Group Ltd Chemical process
KR890000427A (ko) * 1987-06-22 1989-03-14 배리 에이.뉴샘 아미노시클로펜틸 에테르 및 그의 제조방법 및 약제

Also Published As

Publication number Publication date
ZA884649B (en) 1989-03-29
AU615922B2 (en) 1991-10-17
FI883105A0 (fi) 1988-06-29
KR890000425A (ko) 1989-03-14
DK357388A (da) 1988-12-31
NO882883L (no) 1989-01-02
NO882883D0 (no) 1988-06-29
FI883105A (fi) 1988-12-31
DK357388D0 (da) 1988-06-29
PT87861B (pt) 1992-11-30
IL86930A0 (en) 1988-11-30
PH24774A (en) 1990-10-30
IL86548A0 (en) 1988-11-15
CA1312609C (en) 1993-01-12
JPS6422864A (en) 1989-01-25
AU1873388A (en) 1989-01-05
GB8715333D0 (en) 1987-08-05
PT87861A (pt) 1988-07-01
EP0297853A1 (en) 1989-01-04
NZ225221A (en) 1990-10-26
US4933461A (en) 1990-06-12

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