IL82555A0 - Di-and tetrahydroisoquinoline derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
Di-and tetrahydroisoquinoline derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL82555A0 IL82555A0 IL82555A IL8255587A IL82555A0 IL 82555 A0 IL82555 A0 IL 82555A0 IL 82555 A IL82555 A IL 82555A IL 8255587 A IL8255587 A IL 8255587A IL 82555 A0 IL82555 A0 IL 82555A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- tetrahydroisoquinoline derivatives
- tetrahydroisoquinoline
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000003039 tetrahydroisoquinolinyl group Chemical class C1(NCCC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D515/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D515/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8601279 | 1986-05-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL82555A0 true IL82555A0 (en) | 1987-11-30 |
Family
ID=19848040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL82555A IL82555A0 (en) | 1986-05-21 | 1987-05-18 | Di-and tetrahydroisoquinoline derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5162335A (da) |
| EP (1) | EP0251361A1 (da) |
| JP (1) | JPS62283960A (da) |
| AU (1) | AU7314987A (da) |
| CA (1) | CA1330560C (da) |
| DK (1) | DK250387A (da) |
| IL (1) | IL82555A0 (da) |
| NZ (1) | NZ220336A (da) |
| PH (1) | PH25651A (da) |
| ZA (1) | ZA873561B (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8800397D0 (en) * | 1988-01-08 | 1988-02-10 | Sandoz Ltd | Improvements in/relating to organic compounds |
| EP0357122A3 (en) * | 1988-08-29 | 1991-10-23 | Duphar International Research B.V | Use of beta-carbolines, their bio-isosteric benzofuran and benzothiophene analogues for the manufacture of a medicament having cytostatic properties |
| GB8921304D0 (en) * | 1989-09-20 | 1989-11-08 | Wyeth John & Brother Ltd | New method of treatment and heterocyclic compounds used therein |
| US5248677A (en) * | 1990-03-30 | 1993-09-28 | Abbott Laboratories | Biogentic amine uptake inhibitors |
| JPH06504034A (ja) * | 1990-06-11 | 1994-05-12 | バイオケム ファーマ インコーポレイテッド | 複素環式アントラサイクリオンならびにアントラサイクリン類似化合物 |
| US5593970A (en) * | 1990-06-11 | 1997-01-14 | Biochem Pharma Inc. | Heterocyclic anthracycline analogs |
| GB9027055D0 (en) * | 1990-12-13 | 1991-02-06 | Sandoz Ltd | Organic compounds |
| BR9107169A (pt) * | 1990-12-17 | 1993-11-16 | Shell Int Research | Derivados de isoquinolina fungicidas |
| GB9322828D0 (en) * | 1993-11-05 | 1993-12-22 | Sandoz Ltd | Organic compounds |
| US5998620A (en) * | 1997-03-25 | 1999-12-07 | Schering Corporation | Synthesis of intermediates useful in preparing tricyclic compounds |
| US6900228B1 (en) | 1998-03-10 | 2005-05-31 | Research Triangle Institute | Opiate compounds, methods of making and methods of use |
| DE10035997A1 (de) * | 2000-07-25 | 2002-02-07 | Boehringer Ingelheim Pharma | Verwendung von anellierten Dihydropyridinen zur Herstellung von Mitteln für die Behandlung von chronischen Schmerzen |
| SI1732898T1 (sl) * | 2004-03-12 | 2008-06-30 | Analytecon Sa | Tetrahidroizokinolinski in tetrahidrobenzazepinski derivati kot inhibitorji IGF-1R |
| US8507523B2 (en) * | 2006-11-21 | 2013-08-13 | Renukadevi Patil | Therapeutic tetrahydroisoquinoline-based compositions for cancer therapy |
| CN110551066B (zh) * | 2019-09-03 | 2022-03-11 | 云南中烟工业有限责任公司 | 一种从烟草根茎中提取的异喹啉生物碱类化合物及其应用 |
| CN110483536B (zh) * | 2019-09-03 | 2022-03-11 | 云南中烟工业有限责任公司 | 一种从铁刀木中提取的三环异喹啉生物碱类化合物及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1437802A (en) * | 1921-11-26 | 1922-12-05 | Chem Ind Basel | Derivatives of dihydroisoquinoline |
| AT281829B (de) * | 1967-09-11 | 1970-06-10 | Richter Gedeon Vegyeszet | Verfahren zur Herstellung von neuen quartären 1,2-disubstituierten 6,7-Dialkoxy-1,2,3,4-tetrahydroisochinolinderivaten |
| US3597431A (en) * | 1969-07-23 | 1971-08-03 | American Cyanamid Co | 1-(4'-substituted-phenyl)-2-(phenyl lower alkyl)-1,2,3,4-tetrahydroisoquinolines |
| US3629265A (en) * | 1969-10-30 | 1971-12-21 | Hoffmann La Roche | 7-halo-4-isoquinolones |
| US4001244A (en) * | 1973-07-23 | 1977-01-04 | G. D. Searle & Co. | 1-aryl-3,4-dihydro-2(1h)-isoquinoline carbonyl chlorides |
| US4567253A (en) * | 1984-02-03 | 1986-01-28 | Tony Durst | 2-Substituted derivatives of podophyllotoxin and etoposide |
-
1987
- 1987-05-15 PH PH35266A patent/PH25651A/en unknown
- 1987-05-15 CA CA000537195A patent/CA1330560C/en not_active Expired - Fee Related
- 1987-05-18 AU AU73149/87A patent/AU7314987A/en not_active Abandoned
- 1987-05-18 NZ NZ220336A patent/NZ220336A/xx unknown
- 1987-05-18 JP JP62119169A patent/JPS62283960A/ja active Pending
- 1987-05-18 ZA ZA873561A patent/ZA873561B/xx unknown
- 1987-05-18 DK DK250387A patent/DK250387A/da not_active Application Discontinuation
- 1987-05-18 IL IL82555A patent/IL82555A0/xx not_active IP Right Cessation
- 1987-05-19 EP EP87200926A patent/EP0251361A1/en not_active Withdrawn
-
1989
- 1989-11-27 US US07/480,755 patent/US5162335A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0251361A1 (en) | 1988-01-07 |
| NZ220336A (en) | 1990-10-26 |
| DK250387A (da) | 1987-11-22 |
| AU7314987A (en) | 1987-11-26 |
| JPS62283960A (ja) | 1987-12-09 |
| CA1330560C (en) | 1994-07-05 |
| PH25651A (en) | 1991-08-21 |
| DK250387D0 (da) | 1987-05-18 |
| ZA873561B (en) | 1987-11-11 |
| US5162335A (en) | 1992-11-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |