IL80476A0 - Prazosin-pirbuterol combination for bronchodilation - Google Patents
Prazosin-pirbuterol combination for bronchodilationInfo
- Publication number
- IL80476A0 IL80476A0 IL80476A IL8047686A IL80476A0 IL 80476 A0 IL80476 A0 IL 80476A0 IL 80476 A IL80476 A IL 80476A IL 8047686 A IL8047686 A IL 8047686A IL 80476 A0 IL80476 A0 IL 80476A0
- Authority
- IL
- Israel
- Prior art keywords
- pirbuterol
- prazosin
- pharmaceutically acceptable
- bronchodilation
- combination
- Prior art date
Links
- 229960005414 pirbuterol Drugs 0.000 title abstract 2
- 230000007883 bronchodilation Effects 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 206010006482 Bronchospasm Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- VQDBNKDJNJQRDG-UHFFFAOYSA-N Pirbuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=N1 VQDBNKDJNJQRDG-UHFFFAOYSA-N 0.000 abstract 1
- 230000007885 bronchoconstriction Effects 0.000 abstract 1
- 230000003182 bronchodilatating effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- IENZQIKPVFGBNW-UHFFFAOYSA-N prazosin Chemical compound N=1C(N)=C2C=C(OC)C(OC)=CC2=NC=1N(CC1)CCN1C(=O)C1=CC=CO1 IENZQIKPVFGBNW-UHFFFAOYSA-N 0.000 abstract 1
- 229960001289 prazosin Drugs 0.000 abstract 1
- 230000002040 relaxant effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/795,689 US4601897A (en) | 1985-11-06 | 1985-11-06 | Prazosin-pirbuterol combination for bronchodilation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL80476A0 true IL80476A0 (en) | 1987-02-27 |
Family
ID=25166193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL80476A IL80476A0 (en) | 1985-11-06 | 1986-11-03 | Prazosin-pirbuterol combination for bronchodilation |
Country Status (14)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4868182A (en) * | 1986-11-05 | 1989-09-19 | Merrell Dow Pharmaceuticals Inc. | Enhancement of prazosin |
| ZA878182B (en) * | 1986-11-05 | 1988-05-02 | Merrell Dow Pharmaceuticals Inc. | Enhancement of prazosin |
| US5110927A (en) * | 1987-12-31 | 1992-05-05 | The United States Of America As Represented By The Department Of Health And Human Services | Prazosin analog with increased selectivity and duration of action |
| US5225183A (en) * | 1988-12-06 | 1993-07-06 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| US5776434A (en) | 1988-12-06 | 1998-07-07 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| US6048857A (en) * | 1989-10-17 | 2000-04-11 | Ellinwood, Jr.; Everett H. | Dosing method of administering medicaments via inhalation administration |
| US5439670A (en) * | 1989-11-28 | 1995-08-08 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
| US5503869A (en) * | 1994-10-21 | 1996-04-02 | Glaxo Wellcome Inc. | Process for forming medicament carrier for dry powder inhalator |
| JP2008535924A (ja) * | 2005-04-12 | 2008-09-04 | エラン ファーマ インターナショナル リミテッド | ナノ粒子キナゾリン誘導体製剤 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3517005A (en) * | 1967-10-26 | 1970-06-23 | Pfizer & Co C | Certain 2- and 4-substituted quinazolines |
| US3511836A (en) * | 1967-12-13 | 1970-05-12 | Pfizer & Co C | 2,4,6,7-tetra substituted quinazolines |
| US3723434A (en) * | 1970-07-17 | 1973-03-27 | Pfizer | Piperazino isoquinoline bronchodilators |
| US3786160A (en) * | 1971-02-16 | 1974-01-15 | Pfizer | Use of 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-aminoethyl)-pyridines as bronchodilators |
| US3700681A (en) * | 1971-02-16 | 1972-10-24 | Pfizer | 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-aminoethyl)pyridines |
| US4092315A (en) * | 1976-03-01 | 1978-05-30 | Pfizer Inc. | Novel crystalline forms of prazosin hydrochloride |
| GB1591490A (en) * | 1977-08-04 | 1981-06-24 | Abbott Lab | 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate |
| US4175128A (en) * | 1979-01-03 | 1979-11-20 | Pfizer Inc. | Method for treating congestive heart failure |
| FI67699C (fi) * | 1979-01-31 | 1985-05-10 | Orion Yhtymae Oy | Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan |
| DE3235565A1 (de) * | 1982-09-25 | 1984-03-29 | Boehringer Ingelheim KG, 6507 Ingelheim | Piperidinderivate, ihre herstellung und verwendung |
-
1985
- 1985-11-06 US US06/795,689 patent/US4601897A/en not_active Expired - Fee Related
-
1986
- 1986-11-03 IL IL80476A patent/IL80476A0/xx not_active IP Right Cessation
- 1986-11-03 DE DE8686308544T patent/DE3676640D1/de not_active Expired - Lifetime
- 1986-11-03 EP EP86308544A patent/EP0222575B1/en not_active Expired - Lifetime
- 1986-11-03 ES ES198686308544T patent/ES2036174T3/es not_active Expired - Lifetime
- 1986-11-03 AT AT86308544T patent/ATE59295T1/de active
- 1986-11-04 CA CA000522113A patent/CA1284107C/en not_active Expired - Lifetime
- 1986-11-05 JP JP61263624A patent/JPS62135424A/ja active Granted
- 1986-11-05 ZA ZA868427A patent/ZA868427B/xx unknown
- 1986-11-05 IE IE291186A patent/IE59327B1/en not_active IP Right Cessation
- 1986-11-05 AU AU64832/86A patent/AU567018B2/en not_active Ceased
- 1986-11-05 DK DK527186A patent/DK527186A/da not_active Application Discontinuation
- 1986-11-05 NZ NZ218175A patent/NZ218175A/xx unknown
-
1991
- 1991-01-31 GR GR91400121T patent/GR3001420T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE862911L (en) | 1987-05-06 |
| AU567018B2 (en) | 1987-11-05 |
| JPH0524890B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-04-09 |
| EP0222575B1 (en) | 1990-12-27 |
| US4601897A (en) | 1986-07-22 |
| ATE59295T1 (de) | 1991-01-15 |
| JPS62135424A (ja) | 1987-06-18 |
| NZ218175A (en) | 1989-04-26 |
| EP0222575A1 (en) | 1987-05-20 |
| DK527186D0 (da) | 1986-11-05 |
| GR3001420T3 (en) | 1992-09-25 |
| DK527186A (da) | 1987-05-07 |
| ZA868427B (en) | 1988-06-29 |
| AU6483286A (en) | 1987-05-21 |
| DE3676640D1 (de) | 1991-02-07 |
| ES2036174T3 (es) | 1993-05-16 |
| CA1284107C (en) | 1991-05-14 |
| IE59327B1 (en) | 1994-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |