IL73509A - 1,4-dihydro-3-carbamoyl pyridines,their preparation and pharmaceutical compositions comprising them - Google Patents

1,4-dihydro-3-carbamoyl pyridines,their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL73509A
IL73509A IL73509A IL7350984A IL73509A IL 73509 A IL73509 A IL 73509A IL 73509 A IL73509 A IL 73509A IL 7350984 A IL7350984 A IL 7350984A IL 73509 A IL73509 A IL 73509A
Authority
IL
Israel
Prior art keywords
pyridines
carbamoyl
dihydro
preparation
pharmaceutical compositions
Prior art date
Application number
IL73509A
Other languages
English (en)
Other versions
IL73509A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL73509A0 publication Critical patent/IL73509A0/xx
Publication of IL73509A publication Critical patent/IL73509A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL73509A 1983-11-16 1984-11-14 1,4-dihydro-3-carbamoyl pyridines,their preparation and pharmaceutical compositions comprising them IL73509A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH615483 1983-11-16
CH342584 1984-07-13

Publications (2)

Publication Number Publication Date
IL73509A0 IL73509A0 (en) 1985-02-28
IL73509A true IL73509A (en) 1988-05-31

Family

ID=25692968

Family Applications (1)

Application Number Title Priority Date Filing Date
IL73509A IL73509A (en) 1983-11-16 1984-11-14 1,4-dihydro-3-carbamoyl pyridines,their preparation and pharmaceutical compositions comprising them

Country Status (13)

Country Link
EP (1) EP0145956A1 (fr)
KR (1) KR850003713A (fr)
AU (1) AU578633B2 (fr)
DD (1) DD228547A5 (fr)
DK (1) DK543084A (fr)
ES (4) ES8706634A1 (fr)
FI (1) FI844466L (fr)
GR (1) GR80948B (fr)
HU (1) HU193909B (fr)
IL (1) IL73509A (fr)
NO (1) NO844560L (fr)
NZ (1) NZ210223A (fr)
PT (1) PT79498B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994476A (en) * 1984-10-31 1991-02-19 Bristol-Myers Company Dihydropyridin-3,5-dicarboxylates incorporating aryloxypropanolamine moieties
JPH0676405B2 (ja) * 1986-06-13 1994-09-28 日清製粉株式会社 １，４―ジヒドロピリジン誘導体およびそれを含有する医薬組成物
US4808603A (en) * 1985-08-14 1989-02-28 Ciba-Geigy Corporation 3,5-diacyl-2,6-dialkyl-4-aryl-1,4-dihydropyridines, their use, and pharmaceutical compositions thereof
US4771057A (en) * 1986-02-03 1988-09-13 University Of Alberta Reduced pyridyl derivatives with cardiovascular regulating properties
IT1204460B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
DE69131444T2 (de) * 1990-11-30 1999-12-23 Fujirebio Inc., Tokio/Tokyo Optisch aktive 1,4-Dihydropyridinderivate sowie Verfahren zu ihrer Herstellung
EP0536671B1 (fr) * 1991-10-07 1996-03-06 Hoechst Aktiengesellschaft Groupes de protection ester d'acides carboxyliques, procédé pour les synthétiser, leur couplage à un groupe fonctionnel et leur utilisation
US6265417B1 (en) 1997-12-18 2001-07-24 Abbott Laboratories Potassium channel openers
US6593335B1 (en) * 1997-12-18 2003-07-15 Abbott Laboratories Potassium channel openers
CN107857712B (zh) * 2016-09-22 2022-09-09 烟台益诺依生物医药科技有限公司 (r)-3-甲基-2-(3-氧代酰胺基)正丁酸酯

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4285955A (en) * 1978-10-31 1981-08-25 Bayer Aktiengesellschaft 1,4-Dihydropyridinecarboxylic acids
DE3042769A1 (de) * 1980-11-13 1982-06-09 Bayer Ag, 5090 Leverkusen C-3 verknuepfte 1,4-dihydropyridine, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung
FR2508446B1 (fr) * 1981-06-25 1986-05-02 Rhone Poulenc Agrochimie Herbicides a fonctions amide et ester derives de la pyridine ainsi que leur procede de preparation et leur application
EP0111453A1 (fr) * 1982-12-10 1984-06-20 Ciba-Geigy Ag Dérivés d'amides
DE3319956A1 (de) * 1983-06-01 1984-12-06 Bayer Ag, 5090 Leverkusen 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
US4755512A (en) * 1984-04-11 1988-07-05 Bristol-Myers Company Pharmaceutically useful dihydropyridinyldicarboxylate amides and esters incorporating arylpiperazinylalkyl moities

Also Published As

Publication number Publication date
ES537646A0 (es) 1987-06-16
PT79498B (en) 1987-01-13
ES550926A0 (es) 1987-02-16
DK543084D0 (da) 1984-11-15
ES8703424A1 (es) 1987-02-16
NO844560L (no) 1985-05-20
NZ210223A (en) 1988-10-28
KR850003713A (ko) 1985-06-26
DD228547A5 (de) 1985-10-16
PT79498A (en) 1984-12-01
FI844466A0 (fi) 1984-11-14
ES550927A0 (es) 1987-02-16
AU578633B2 (en) 1988-11-03
EP0145956A1 (fr) 1985-06-26
ES8706634A1 (es) 1987-06-16
HUT35645A (en) 1985-07-29
IL73509A0 (en) 1985-02-28
ES8703428A1 (es) 1987-02-16
FI844466L (fi) 1985-05-17
AU3547484A (en) 1985-05-23
GR80948B (en) 1985-03-01
ES550928A0 (es) 1987-02-16
ES8703427A1 (es) 1987-02-16
HU193909B (en) 1987-12-28
DK543084A (da) 1985-05-17

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