IL72487A - Angiotensin-converting enzyme inhibiting hydrogenated oxoindolizine-(and oxoquinolizine)propanoic acids,their preparation and pharmaceutical compositions containing them - Google Patents
Angiotensin-converting enzyme inhibiting hydrogenated oxoindolizine-(and oxoquinolizine)propanoic acids,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL72487A IL72487A IL72487A IL7248784A IL72487A IL 72487 A IL72487 A IL 72487A IL 72487 A IL72487 A IL 72487A IL 7248784 A IL7248784 A IL 7248784A IL 72487 A IL72487 A IL 72487A
- Authority
- IL
- Israel
- Prior art keywords
- oxoquinolizine
- oxoindolizine
- angiotensin
- hydrogenated
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/519,360 US4594431A (en) | 1983-08-01 | 1983-08-01 | Octahydroindolizinepropanoic acids and related compounds as enzyme inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL72487A0 IL72487A0 (en) | 1984-11-30 |
| IL72487A true IL72487A (en) | 1988-03-31 |
Family
ID=24067968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL72487A IL72487A (en) | 1983-08-01 | 1984-07-24 | Angiotensin-converting enzyme inhibiting hydrogenated oxoindolizine-(and oxoquinolizine)propanoic acids,their preparation and pharmaceutical compositions containing them |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4594431A (da) |
| EP (1) | EP0133038A3 (da) |
| JP (1) | JPS60115579A (da) |
| KR (1) | KR870000340B1 (da) |
| CA (1) | CA1257268A (da) |
| DK (1) | DK371684A (da) |
| GB (1) | GB2144421B (da) |
| GR (1) | GR82660B (da) |
| HU (1) | HU199461B (da) |
| IL (1) | IL72487A (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998005333A1 (en) * | 1996-08-05 | 1998-02-12 | Molecumetics Ltd. | Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors |
| EP1661566A3 (en) * | 1996-08-05 | 2008-04-16 | Myriad Genetics, Inc. | Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors |
| US7498310B1 (en) | 1998-08-13 | 2009-03-03 | Beiersdorf Ag | Cosmetic or dermatological preparations comprising oligopeptides for lightening the skin of age marks and/or for preventing tanning of the skin, in particular tanning of the skin caused by UV radiation |
| US6841559B1 (en) | 1999-11-19 | 2005-01-11 | Washington University Of St. Louis | Pyridinones to treat and prevent bacterial infections |
| AU1923501A (en) * | 1999-11-19 | 2001-05-30 | Washington University | Pyridinones to treat and prevent bacterial infections |
| WO2005102330A2 (en) | 2004-04-16 | 2005-11-03 | Washingtion University | Amino methylated 2-pyridinones |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3274202A (en) * | 1963-04-02 | 1966-09-20 | Mcneilab Inc | Certain octohydro-3-oxo-indolizines |
| US3297704A (en) * | 1965-07-01 | 1967-01-10 | Mcneilab Inc | Octahydro-3-oxo indolizine carboxylates |
| US3494929A (en) * | 1967-07-25 | 1970-02-10 | American Home Prod | 1-keto octahydroquinolizine-4-carboxylic acids |
| US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
| US4154935A (en) * | 1978-02-21 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Halogen substituted mercaptoacylamino acids |
| US4316906A (en) * | 1978-08-11 | 1982-02-23 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of substituted prolines |
| US4316905A (en) * | 1980-07-01 | 1982-02-23 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of various 4-substituted prolines |
| US4508901A (en) * | 1982-08-19 | 1985-04-02 | Eli Lilly And Company | Quiuolizine and indolizine enzyme inhibitors |
| US4404282A (en) * | 1982-08-19 | 1983-09-13 | Eli Lilly And Company | Process for enzyme inhibitor |
| US4404281A (en) * | 1982-08-19 | 1983-09-13 | Eli Lilly And Company | Process for enzyme inhibitors |
-
1983
- 1983-08-01 US US06/519,360 patent/US4594431A/en not_active Expired - Fee Related
-
1984
- 1984-07-24 CA CA000459504A patent/CA1257268A/en not_active Expired
- 1984-07-24 IL IL72487A patent/IL72487A/xx unknown
- 1984-07-27 EP EP84305133A patent/EP0133038A3/en not_active Ceased
- 1984-07-27 GB GB08419279A patent/GB2144421B/en not_active Expired
- 1984-07-30 GR GR75450A patent/GR82660B/el unknown
- 1984-07-30 HU HU842920A patent/HU199461B/hu not_active IP Right Cessation
- 1984-07-31 JP JP59162758A patent/JPS60115579A/ja active Pending
- 1984-07-31 KR KR1019840004550A patent/KR870000340B1/ko not_active IP Right Cessation
- 1984-07-31 DK DK371684A patent/DK371684A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GB8419279D0 (en) | 1984-08-30 |
| DK371684D0 (da) | 1984-07-31 |
| GB2144421A (en) | 1985-03-06 |
| DK371684A (da) | 1985-02-02 |
| EP0133038A3 (en) | 1988-01-07 |
| HUT34476A (en) | 1985-03-28 |
| GR82660B (da) | 1985-02-07 |
| IL72487A0 (en) | 1984-11-30 |
| KR850002093A (ko) | 1985-05-06 |
| EP0133038A2 (en) | 1985-02-13 |
| GB2144421B (en) | 1987-01-07 |
| KR870000340B1 (ko) | 1987-03-04 |
| US4594431A (en) | 1986-06-10 |
| JPS60115579A (ja) | 1985-06-22 |
| HU199461B (en) | 1990-02-28 |
| CA1257268A (en) | 1989-07-11 |
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