IL71987A - N-(beta-fluoroethyl)nortropine,its preparation and use in preparation of the corresponding 3-alpha-benzilate - Google Patents

N-(beta-fluoroethyl)nortropine,its preparation and use in preparation of the corresponding 3-alpha-benzilate

Info

Publication number
IL71987A
IL71987A IL71987A IL7198784A IL71987A IL 71987 A IL71987 A IL 71987A IL 71987 A IL71987 A IL 71987A IL 7198784 A IL7198784 A IL 7198784A IL 71987 A IL71987 A IL 71987A
Authority
IL
Israel
Prior art keywords
preparation
nortropine
benzilate
fluoroethyl
beta
Prior art date
Application number
IL71987A
Other languages
English (en)
Other versions
IL71987A0 (en
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of IL71987A0 publication Critical patent/IL71987A0/xx
Publication of IL71987A publication Critical patent/IL71987A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL71987A 1983-06-03 1984-06-01 N-(beta-fluoroethyl)nortropine,its preparation and use in preparation of the corresponding 3-alpha-benzilate IL71987A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833320138 DE3320138A1 (de) 1983-06-03 1983-06-03 Neues nortropinderivat, verfahren zu seiner herstellung und seine verwendung

Publications (2)

Publication Number Publication Date
IL71987A0 IL71987A0 (en) 1984-10-31
IL71987A true IL71987A (en) 1989-07-31

Family

ID=6200592

Family Applications (1)

Application Number Title Priority Date Filing Date
IL71987A IL71987A (en) 1983-06-03 1984-06-01 N-(beta-fluoroethyl)nortropine,its preparation and use in preparation of the corresponding 3-alpha-benzilate

Country Status (6)

Country Link
US (1) US4549021A (xx)
EP (1) EP0128437B1 (xx)
JP (1) JPS606687A (xx)
AT (1) ATE32719T1 (xx)
DE (2) DE3320138A1 (xx)
IL (1) IL71987A (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2630439A1 (fr) * 1988-04-22 1989-10-27 Agronomique Inst Nat Rech Composes chimiques et isomeres, leur preparation et leur utilisation pour la selection de microorganismes, procede pour cette selection et produit utilise
DE4108393A1 (de) * 1991-03-15 1992-09-17 Boehringer Ingelheim Kg Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3505337A (en) * 1967-12-22 1970-04-07 Boehringer Sohn Ingelheim N - hydrocarbyl-substituted noratropinium,haloalkylates and o-acyl derivatives thereof
DE2026661A1 (de) * 1970-06-01 1971-12-16 C H Boehnnger Sohn, 6507 Ingelheim Tropan 3 öl Derivate und Verfahren zu deren Herstellung
DE2540633A1 (de) * 1975-09-12 1977-04-28 Boehringer Sohn Ingelheim Neue quartaere n-beta-substituierte benzilsaeure-n-alkyl-nortropinester und verfahren zu deren herstellung
US4486441A (en) * 1982-12-03 1984-12-04 Merrell Toraude Et Compagnie Pseudotropyl halogeno-benzoates and their use in migraine treatment

Also Published As

Publication number Publication date
ATE32719T1 (de) 1988-03-15
DE3320138A1 (de) 1984-12-06
EP0128437A2 (de) 1984-12-19
DE3469527D1 (en) 1988-04-07
JPH0446276B2 (xx) 1992-07-29
EP0128437B1 (de) 1988-03-02
IL71987A0 (en) 1984-10-31
US4549021A (en) 1985-10-22
EP0128437A3 (en) 1985-10-30
JPS606687A (ja) 1985-01-14

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Legal Events

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