IL71819A - Pharmaceutical composition for treatment of neurological disease or aging containing amino acids together with choline - Google Patents
Pharmaceutical composition for treatment of neurological disease or aging containing amino acids together with cholineInfo
- Publication number
- IL71819A IL71819A IL71819A IL7181984A IL71819A IL 71819 A IL71819 A IL 71819A IL 71819 A IL71819 A IL 71819A IL 7181984 A IL7181984 A IL 7181984A IL 71819 A IL71819 A IL 71819A
- Authority
- IL
- Israel
- Prior art keywords
- choline
- pharmaceutical composition
- neurological disease
- treatment
- amino acids
- Prior art date
Links
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 title abstract 4
- 229960001231 choline Drugs 0.000 title abstract 4
- 208000012902 Nervous system disease Diseases 0.000 title abstract 2
- 208000025966 Neurological disease Diseases 0.000 title abstract 2
- 230000032683 aging Effects 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000002243 precursor Substances 0.000 abstract 2
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 abstract 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 239000002858 neurotransmitter agent Substances 0.000 abstract 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49520283A | 1983-05-16 | 1983-05-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL71819A0 IL71819A0 (en) | 1984-09-30 |
| IL71819A true IL71819A (en) | 1987-12-31 |
Family
ID=23967687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL71819A IL71819A (en) | 1983-05-16 | 1984-05-13 | Pharmaceutical composition for treatment of neurological disease or aging containing amino acids together with choline |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0125900B1 (de) |
| JP (1) | JPS60214734A (de) |
| AT (1) | ATE45672T1 (de) |
| CA (1) | CA1228301A (de) |
| DE (1) | DE3479477D1 (de) |
| ES (1) | ES8602409A1 (de) |
| GR (1) | GR79973B (de) |
| IL (1) | IL71819A (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2657013B1 (fr) * | 1990-01-18 | 1992-05-15 | Medgenix Group Sa | Composition dietetique a base de polypeptides et acides amines. |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1114295A (en) * | 1977-11-02 | 1981-12-15 | John H. Growdon | Process and composition for treating disorders by administering choline or a compound that dissociates to choline |
| US4296119A (en) * | 1978-04-24 | 1981-10-20 | Massachusetts Institute Of Technology | Process and composition for reducing blood pressure in animals |
| DE2962429D1 (en) * | 1978-04-24 | 1982-05-19 | Massachusetts Inst Technology | A pharmaceutical composition comprising an amino acid for reducing blood serum prolactin levels |
| EP0005058B1 (de) * | 1978-04-24 | 1984-10-17 | Massachusetts Institute Of Technology | Zusammensetzung zur Regulierung des Dopamin- oder Norepinephrin-Spiegels in Neuronen-Synapsen |
| JPS5566512A (en) * | 1978-11-15 | 1980-05-20 | Massachusetts Inst Technology | Method and composition for treating difficulties by administration of choline or choline dissociating compound |
| US4221784A (en) * | 1979-04-05 | 1980-09-09 | Massachusetts Institute Of Technology | Process and composition for treating disorders by administering lecithin |
| DE2915433A1 (de) * | 1979-04-17 | 1980-10-30 | Christensen Plantorgan Werk | Verwendung von physiologisch vertraeglichen methyldonatoren |
| US4397866A (en) * | 1979-05-07 | 1983-08-09 | Massachusetts Institute Of Technology | Process for increasing glycine levels in the brain and spinal cord |
-
1984
- 1984-05-11 DE DE8484303195T patent/DE3479477D1/de not_active Expired
- 1984-05-11 EP EP84303195A patent/EP0125900B1/de not_active Expired
- 1984-05-11 AT AT84303195T patent/ATE45672T1/de not_active IP Right Cessation
- 1984-05-13 IL IL71819A patent/IL71819A/xx not_active IP Right Cessation
- 1984-05-14 JP JP59094739A patent/JPS60214734A/ja active Granted
- 1984-05-15 ES ES532873A patent/ES8602409A1/es not_active Expired
- 1984-05-16 GR GR74742A patent/GR79973B/el unknown
- 1984-05-16 CA CA000454518A patent/CA1228301A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ATE45672T1 (de) | 1989-09-15 |
| IL71819A0 (en) | 1984-09-30 |
| ES532873A0 (es) | 1985-12-16 |
| ES8602409A1 (es) | 1985-12-16 |
| DE3479477D1 (en) | 1989-09-28 |
| JPS60214734A (ja) | 1985-10-28 |
| CA1228301A (en) | 1987-10-20 |
| EP0125900A1 (de) | 1984-11-21 |
| JPH0141124B2 (de) | 1989-09-04 |
| GR79973B (de) | 1984-10-31 |
| EP0125900B1 (de) | 1989-08-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |