IL70698A - Indole derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Indole derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL70698A
IL70698A IL70698A IL7069884A IL70698A IL 70698 A IL70698 A IL 70698A IL 70698 A IL70698 A IL 70698A IL 7069884 A IL7069884 A IL 7069884A IL 70698 A IL70698 A IL 70698A
Authority
IL
Israel
Prior art keywords
alkyl
indole derivatives
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL70698A
Other versions
IL70698A0 (en
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of IL70698A0 publication Critical patent/IL70698A0/en
Publication of IL70698A publication Critical patent/IL70698A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1. Indole derivatives of the general formula I see diagramm : EP0114603,P10,F1 in which Ind is a 3-indolyl radical which can be substituted once or twice by alkyl, O-alkyl, S-alkyl, SO-alkyl, SO2 -alkyl, OH, F, CL, Br, CF3 and/or CN or by a methylenedioxy group, A is -(CH2 )n -, n is 3, 4 or 5, Ar is a hydroxyphenyl group and the two radicals L are each H or together are a C-C bond, and in which the alkyl groups each have 1-4 C atoms, and their physiologically acceptable acid addition salts.
IL70698A 1983-01-20 1984-01-16 Indole derivatives,their preparation and pharmaceutical compositions containing them IL70698A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3301758A DE3301758A1 (en) 1983-01-20 1983-01-20 INDOLDER DERIVATIVES

Publications (2)

Publication Number Publication Date
IL70698A0 IL70698A0 (en) 1984-04-30
IL70698A true IL70698A (en) 1987-03-31

Family

ID=6188727

Family Applications (1)

Application Number Title Priority Date Filing Date
IL70698A IL70698A (en) 1983-01-20 1984-01-16 Indole derivatives,their preparation and pharmaceutical compositions containing them

Country Status (11)

Country Link
EP (1) EP0114603B1 (en)
JP (1) JPS59181276A (en)
AT (1) ATE34983T1 (en)
AU (1) AU565894B2 (en)
CA (1) CA1257273A (en)
DE (2) DE3301758A1 (en)
ES (1) ES529013A0 (en)
FI (1) FI840225A7 (en)
HU (1) HU193196B (en)
IL (1) IL70698A (en)
ZA (1) ZA84424B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3342632A1 (en) * 1983-11-25 1985-06-05 Merck Patent Gmbh, 6100 Darmstadt INDOLDER DERIVATIVES
DE3604949A1 (en) * 1986-02-17 1987-08-20 Merck Patent Gmbh HYDROXYINDOLESTER
DE3614758A1 (en) * 1986-04-30 1987-11-05 Merck Patent Gmbh INDOLDER DERIVATIVE

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238215A (en) * 1963-10-17 1966-03-01 Sterling Drug Inc 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
SE307788B (en) * 1965-04-23 1969-01-20 Yoshitomi Pharmaceutical
US4160862A (en) * 1972-06-12 1979-07-10 Sterling Drug Inc. 1-Acyl-3-(amino-lower-alkyl)indoles
DE2708913A1 (en) * 1976-03-04 1977-09-08 Hoechst Ag BENZOYL PIPERIDYALKYL INDOLES AND RELATED COMPOUNDS
DE2961867D1 (en) * 1978-06-24 1982-03-04 Merck Patent Gmbh Indolylalkyl amines, pharmaceutical preparations containing them and process for their manufacture
EP0077607A1 (en) * 1981-09-17 1983-04-27 Beecham Group Plc N-substituted 3-aryl piperidines and derivatives thereof

Also Published As

Publication number Publication date
ZA84424B (en) 1984-09-26
EP0114603B1 (en) 1988-06-08
FI840225L (en) 1984-07-21
HU193196B (en) 1987-08-28
EP0114603A1 (en) 1984-08-01
JPS59181276A (en) 1984-10-15
CA1257273A (en) 1989-07-11
ATE34983T1 (en) 1988-06-15
AU565894B2 (en) 1987-10-01
DE3301758A1 (en) 1984-07-26
AU2302484A (en) 1984-07-26
ES8503679A1 (en) 1985-03-01
FI840225A0 (en) 1984-01-19
FI840225A7 (en) 1984-07-22
DE3471935D1 (en) 1988-07-14
ES529013A0 (en) 1985-03-01
IL70698A0 (en) 1984-04-30

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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees