IL69659A - 6-(2-(cyclic amino)ethylamino)tetrahydrotriazolo(3,4-a)phthalazines,their preparation and pharmaceutical compositions containing them - Google Patents
6-(2-(cyclic amino)ethylamino)tetrahydrotriazolo(3,4-a)phthalazines,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL69659A IL69659A IL69659A IL6965983A IL69659A IL 69659 A IL69659 A IL 69659A IL 69659 A IL69659 A IL 69659A IL 6965983 A IL6965983 A IL 6965983A IL 69659 A IL69659 A IL 69659A
- Authority
- IL
- Israel
- Prior art keywords
- cyclic amino
- tetrahydrotriazolo
- phthalazines
- ethylamino
- preparation
- Prior art date
Links
- 125000000031 ethylamino group Chemical group [H]C([H])([H])C([H])([H])N([H])[*] 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003973 alkyl amines Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 229940124630 bronchodilator Drugs 0.000 abstract 1
- 239000000168 bronchodilator agent Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/414,766 US4487930A (en) | 1982-09-07 | 1982-09-07 | 6-[(Cyclic amino)alkylamino]-tetrahydrotriazolo[3,4-a]phthalazines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL69659A0 IL69659A0 (en) | 1983-12-30 |
| IL69659A true IL69659A (en) | 1986-08-31 |
Family
ID=23642869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL69659A IL69659A (en) | 1982-09-07 | 1983-09-05 | 6-(2-(cyclic amino)ethylamino)tetrahydrotriazolo(3,4-a)phthalazines,their preparation and pharmaceutical compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4487930A (cs) |
| EP (1) | EP0104506B1 (cs) |
| JP (1) | JPS5965092A (cs) |
| KR (1) | KR880002685B1 (cs) |
| AT (1) | ATE23339T1 (cs) |
| AU (1) | AU555725B2 (cs) |
| CA (1) | CA1204753A (cs) |
| DE (1) | DE3367393D1 (cs) |
| DK (1) | DK160310C (cs) |
| ES (1) | ES525368A0 (cs) |
| GR (1) | GR78970B (cs) |
| IE (1) | IE55908B1 (cs) |
| IL (1) | IL69659A (cs) |
| NO (1) | NO833181L (cs) |
| NZ (1) | NZ205493A (cs) |
| PH (1) | PH18334A (cs) |
| ZA (1) | ZA836551B (cs) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1194310B (it) * | 1983-07-12 | 1988-09-14 | Lepetit Spa | Derivati triazolo (3,4-a) ftalazinici 3,6-disostituiti |
| US5011835A (en) * | 1990-02-07 | 1991-04-30 | Merrell Dow Pharmaceuticals Inc. | Substituted triazolopyridazines, pharmaceutical compositions and use |
| ES2194205T3 (es) | 1996-07-25 | 2003-11-16 | Merck Sharp & Dohme | Derivados de triazolo-piridazina sustituidos como ligandos para los receptores gaba. |
| US6989080B2 (en) * | 2003-06-19 | 2006-01-24 | Albany International Corp. | Nonwoven neutral line dryer fabric |
| PH12012501361A1 (en) | 2009-12-31 | 2012-10-22 | Centro Nac De Investigaciones Oncologicas Cnio | Tricyclic compounds for use as kinase inhibitors |
| WO2012098387A1 (en) | 2011-01-18 | 2012-07-26 | Centro Nacional De Investigaciones Oncológicas (Cnio) | 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors |
| WO2013005041A1 (en) | 2011-07-07 | 2013-01-10 | Centro Nacional De Investigaciones Oncológicas (Cnio) | Tricyclic heterocyclic compounds as kinase inhibitors |
| WO2013004984A1 (en) | 2011-07-07 | 2013-01-10 | Centro Nacional De Investigaciones Oncologicas (Cnio) | Tricyclic compounds for use as kinase inhibitors |
| WO2013005057A1 (en) | 2011-07-07 | 2013-01-10 | Centro Nacional De Investigaciones Oncológicas (Cnio) | New compounds |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA883836A (en) * | 1971-10-19 | H. De Ruiter Ernest | Selective hydrogenation of tri- and tetrazoloisquinolines | |
| US2484629A (en) * | 1943-11-27 | 1949-10-11 | Squibb & Sons Inc | 2-sulfanilamido-4-alkoxymethyl-6-methyl-pyrimidines and their preparation |
| FR1248409A (fr) * | 1957-06-13 | 1960-12-16 | Bellon Labor Sa Roger | Perfectionnements aux procédés de préparation de dérivés de la triazolo [4-3,b]pyridazine |
| US3096329A (en) * | 1957-10-15 | 1963-07-02 | Sterling Drug Inc | Triazolo [b] pyridazines |
| US3079392A (en) * | 1961-04-27 | 1963-02-26 | Pesson Marcel | Triazolo(4-3, b)pyridazines |
| NL128591C (cs) * | 1965-07-02 | |||
| FR2068082A6 (cs) * | 1969-11-27 | 1971-08-20 | Guinard Pompes | |
| US3915968A (en) * | 1973-09-21 | 1975-10-28 | Lepetit Spa | Triazolopyridazines |
| JPS5516450B2 (cs) * | 1974-08-16 | 1980-05-02 | ||
| US4016162A (en) * | 1974-08-27 | 1977-04-05 | Gruppo Lepetit S.P.A. | 6-Morpholino-3-substituted phenyl-S-triazolo[4,3-b]pyridazines |
| US4136182A (en) * | 1976-05-26 | 1979-01-23 | The Dow Chemical Company | Triazolopyridazines used to alleviate bronchial spasms |
| CA1080712A (en) * | 1976-09-22 | 1980-07-01 | Jay D. Albright | Hypotensive agents |
| US4112095A (en) * | 1976-10-07 | 1978-09-05 | American Cyanamid Company | 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazine hypotensive agents |
| US4272535A (en) * | 1978-07-31 | 1981-06-09 | Schering Corporation | 2,4-[1H,3H,5H]-(1)-Benzopyrano-[2,3-d]-pyrimidinediones and their use as anti-allergy agents |
| GR70309B (cs) * | 1979-10-29 | 1982-09-08 | Dow Chemical Co |
-
1982
- 1982-09-07 US US06/414,766 patent/US4487930A/en not_active Expired - Lifetime
-
1983
- 1983-09-02 JP JP58160604A patent/JPS5965092A/ja active Granted
- 1983-09-02 ZA ZA836551A patent/ZA836551B/xx unknown
- 1983-09-02 GR GR72367A patent/GR78970B/el unknown
- 1983-09-05 PH PH29493A patent/PH18334A/en unknown
- 1983-09-05 AU AU18713/83A patent/AU555725B2/en not_active Ceased
- 1983-09-05 ES ES525368A patent/ES525368A0/es active Granted
- 1983-09-05 NZ NZ205493A patent/NZ205493A/en unknown
- 1983-09-05 DE DE8383108711T patent/DE3367393D1/de not_active Expired
- 1983-09-05 IL IL69659A patent/IL69659A/xx not_active IP Right Cessation
- 1983-09-05 AT AT83108711T patent/ATE23339T1/de not_active IP Right Cessation
- 1983-09-05 EP EP83108711A patent/EP0104506B1/en not_active Expired
- 1983-09-06 DK DK404383A patent/DK160310C/da not_active IP Right Cessation
- 1983-09-06 KR KR1019830004193A patent/KR880002685B1/ko not_active Expired
- 1983-09-06 IE IE2096/83A patent/IE55908B1/en not_active IP Right Cessation
- 1983-09-06 CA CA000438466A patent/CA1204753A/en not_active Expired
- 1983-09-06 NO NO833181A patent/NO833181L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU1871383A (en) | 1984-03-15 |
| EP0104506A1 (en) | 1984-04-04 |
| EP0104506B1 (en) | 1986-11-05 |
| PH18334A (en) | 1985-06-05 |
| ATE23339T1 (de) | 1986-11-15 |
| JPH0378396B2 (cs) | 1991-12-13 |
| IE832096L (en) | 1984-03-07 |
| IE55908B1 (en) | 1991-02-14 |
| DK160310B (da) | 1991-02-25 |
| NZ205493A (en) | 1985-09-13 |
| DK404383A (da) | 1984-03-08 |
| ZA836551B (en) | 1984-04-25 |
| KR880002685B1 (ko) | 1988-12-20 |
| ES8601985A1 (es) | 1985-12-01 |
| KR840006247A (ko) | 1984-11-22 |
| US4487930A (en) | 1984-12-11 |
| DE3367393D1 (de) | 1986-12-11 |
| AU555725B2 (en) | 1986-10-09 |
| ES525368A0 (es) | 1985-12-01 |
| CA1204753A (en) | 1986-05-20 |
| NO833181L (no) | 1984-03-08 |
| DK160310C (da) | 1991-07-29 |
| IL69659A0 (en) | 1983-12-30 |
| GR78970B (cs) | 1984-10-02 |
| DK404383D0 (da) | 1983-09-06 |
| JPS5965092A (ja) | 1984-04-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |