IL67485A0 - Processes and intermediates for the preparation of flutroline - Google Patents
Processes and intermediates for the preparation of flutrolineInfo
- Publication number
- IL67485A0 IL67485A0 IL67485A IL6748582A IL67485A0 IL 67485 A0 IL67485 A0 IL 67485A0 IL 67485 A IL67485 A IL 67485A IL 6748582 A IL6748582 A IL 6748582A IL 67485 A0 IL67485 A0 IL 67485A0
- Authority
- IL
- Israel
- Prior art keywords
- flutroline
- intermediates
- processes
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
- C07C33/48—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
- C07C33/483—Monocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/88—Unsaturated compounds containing keto groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/331,494 US4510308A (en) | 1981-12-17 | 1981-12-17 | Process for preparing carboline derivatives |
| US33419581A | 1981-12-24 | 1981-12-24 | |
| US06/425,152 US4467090A (en) | 1982-09-30 | 1982-09-30 | Compound, 8-fluoro-5-(p-fluorophenyl)-2-[4-(p-fluorophenyl)-4-hydroxybutyryl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole |
| US06/425,151 US4477669A (en) | 1982-09-30 | 1982-09-30 | Processes and intermediates useful in the preparation of flutroline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL67485A0 true IL67485A0 (en) | 1983-05-15 |
Family
ID=27502448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL67485A IL67485A0 (en) | 1981-12-17 | 1982-12-15 | Processes and intermediates for the preparation of flutroline |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0082658A3 (da) |
| AU (1) | AU537294B2 (da) |
| DD (1) | DD209630A5 (da) |
| DK (1) | DK557782A (da) |
| ES (3) | ES518277A0 (da) |
| FI (1) | FI824331L (da) |
| IL (1) | IL67485A0 (da) |
| NO (1) | NO824230L (da) |
| PT (1) | PT75991B (da) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4001263A (en) * | 1974-04-01 | 1977-01-04 | Pfizer Inc. | 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines |
| US4014890A (en) * | 1976-03-23 | 1977-03-29 | Pfizer Inc. | Process for preparing indole derivatives |
| US4044137A (en) * | 1976-07-07 | 1977-08-23 | Pfizer Inc. | 2-(Phenylthiopropyl)-5-aryl-1,2,3,4-tetrahydro-γ-carbolines |
| US4267331A (en) * | 1979-01-23 | 1981-05-12 | Pfizer Inc. | Process for the production of 2-substituted pyrido[4,3-b]-indoles |
-
1982
- 1982-12-13 EP EP82306650A patent/EP0082658A3/en not_active Withdrawn
- 1982-12-15 IL IL67485A patent/IL67485A0/xx unknown
- 1982-12-16 FI FI824331A patent/FI824331L/fi not_active Application Discontinuation
- 1982-12-16 AU AU91595/82A patent/AU537294B2/en not_active Expired - Fee Related
- 1982-12-16 DK DK557782A patent/DK557782A/da not_active Application Discontinuation
- 1982-12-16 PT PT75991A patent/PT75991B/pt unknown
- 1982-12-16 DD DD82246075A patent/DD209630A5/de unknown
- 1982-12-16 NO NO824230A patent/NO824230L/no unknown
- 1982-12-16 ES ES518277A patent/ES518277A0/es active Granted
-
1983
- 1983-08-05 ES ES524776A patent/ES8604732A1/es not_active Expired
- 1983-08-05 ES ES524777A patent/ES8604733A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU537294B2 (en) | 1984-06-14 |
| FI824331A7 (fi) | 1983-06-18 |
| EP0082658A3 (en) | 1984-06-06 |
| PT75991A (en) | 1983-01-01 |
| ES524776A0 (es) | 1984-12-16 |
| FI824331A0 (fi) | 1982-12-16 |
| FI824331L (fi) | 1983-06-18 |
| ES8402296A1 (es) | 1984-01-16 |
| DD209630A5 (de) | 1984-05-16 |
| ES8604732A1 (es) | 1984-12-16 |
| AU9159582A (en) | 1983-08-04 |
| ES524777A0 (es) | 1984-12-16 |
| ES8604733A1 (es) | 1984-12-16 |
| DK557782A (da) | 1983-06-18 |
| EP0082658A2 (en) | 1983-06-29 |
| ES518277A0 (es) | 1984-01-16 |
| NO824230L (no) | 1983-06-20 |
| PT75991B (en) | 1985-12-20 |
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