IL66286A - Crystalline beta form of(3s-(3alpha(z),4beta))-3-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)-acetyl)amino)-4-methyl-2-oxo-1-azetidinesulfonic acid and method for preparation thereof - Google Patents

Crystalline beta form of(3s-(3alpha(z),4beta))-3-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)-acetyl)amino)-4-methyl-2-oxo-1-azetidinesulfonic acid and method for preparation thereof

Info

Publication number
IL66286A
IL66286A IL66286A IL6628682A IL66286A IL 66286 A IL66286 A IL 66286A IL 66286 A IL66286 A IL 66286A IL 6628682 A IL6628682 A IL 6628682A IL 66286 A IL66286 A IL 66286A
Authority
IL
Israel
Prior art keywords
amino
methylethoxy
imino
thiazolyl
oxo
Prior art date
Application number
IL66286A
Other languages
English (en)
Other versions
IL66286A0 (en
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IL66286A0 publication Critical patent/IL66286A0/xx
Publication of IL66286A publication Critical patent/IL66286A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
IL66286A 1981-07-13 1982-07-09 Crystalline beta form of(3s-(3alpha(z),4beta))-3-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)-acetyl)amino)-4-methyl-2-oxo-1-azetidinesulfonic acid and method for preparation thereof IL66286A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28263681A 1981-07-13 1981-07-13

Publications (2)

Publication Number Publication Date
IL66286A0 IL66286A0 (en) 1982-11-30
IL66286A true IL66286A (en) 1986-03-31

Family

ID=23082417

Family Applications (1)

Application Number Title Priority Date Filing Date
IL66286A IL66286A (en) 1981-07-13 1982-07-09 Crystalline beta form of(3s-(3alpha(z),4beta))-3-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)-acetyl)amino)-4-methyl-2-oxo-1-azetidinesulfonic acid and method for preparation thereof

Country Status (11)

Country Link
EP (1) EP0070024B1 (fr)
JP (1) JPS5823689A (fr)
AT (1) ATE14016T1 (fr)
AU (1) AU557096B2 (fr)
CA (1) CA1181075A (fr)
DE (1) DE3264415D1 (fr)
IE (1) IE53109B1 (fr)
IL (1) IL66286A (fr)
NZ (1) NZ201000A (fr)
PH (1) PH19140A (fr)
ZA (1) ZA824418B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982001873A1 (fr) * 1980-12-05 1982-06-10 Takeda Chemical Industries Ltd Derives 1-sulfo-2-oxoazetidine et leur procede de preparation
EP0117053A1 (fr) * 1983-02-10 1984-08-29 Ajinomoto Co., Inc. Dérivés de l'azétidinone
US4826973A (en) * 1984-07-20 1989-05-02 E. R. Squibb & Sons, Inc. Delta form of aztreonam and preparation thereof
US4638062A (en) * 1985-06-17 1987-01-20 E. R. Squibb & Sons, Inc. 3-acylamino-2-oxo-1-azetidinesulfonic acids
CA1339136C (fr) * 1987-07-01 1997-07-29 Sailesh Amilal Varia Forme amorphe de l'aztreonam
AU2002231244B2 (en) 2000-12-27 2006-06-29 Gilead Sciences, Inc. Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections
US7214364B2 (en) 2000-12-27 2007-05-08 Corus Pharma, Inc. Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
CN1545514A (zh) * 2001-08-27 2004-11-10 阿拉宾度药业有限公司 β型晶体无水氨曲南的生产方法
EP1527072A1 (fr) 2002-08-05 2005-05-04 Teva Gyogyszergyar Reszvenytarsasag Preparation d'aztreonam
AU2002356646A1 (en) * 2002-12-11 2004-06-30 Pari Gmbh Pharmaceutical compositions for the pulmonary delivery of aztreonam
EP1622900A1 (fr) * 2003-05-15 2006-02-08 Teva Gyogyszergyar Reszvenytarsasag Polymorphe de beta-aztreonam avec tres faible contenu en solvant residuel
WO2005005424A1 (fr) 2003-07-02 2005-01-20 TEVA Gyógyszergyár Részvénytársaság L-lysine d'aztreonam et procedes de preparation associes
MX2007000526A (es) 2005-05-09 2007-03-28 Sicor Inc Proceso para elaborar aztreonam.
CN102311431B (zh) * 2011-08-30 2014-12-10 海南海药股份有限公司 一种制备无水β-氨曲南的方法
CN111018746A (zh) * 2019-12-16 2020-04-17 山东金城柯瑞化学有限公司 一种氨曲南主环合成中间体n-苄氧羰基-l-苏氨酸酰胺的合成方法
CN112645943A (zh) * 2020-12-25 2021-04-13 南京华盖制药有限公司 一种含氨曲南无定型系统的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ196202A (en) * 1980-02-07 1984-07-31 Squibb & Sons Inc Beta-lactam antibiotics (of azetidine-sulphonic acid type)

Also Published As

Publication number Publication date
ZA824418B (en) 1983-04-27
AU8501082A (en) 1983-01-20
IL66286A0 (en) 1982-11-30
DE3264415D1 (en) 1985-08-01
CA1181075A (fr) 1985-01-15
EP0070024B1 (fr) 1985-06-26
IE821440L (en) 1983-01-13
EP0070024A1 (fr) 1983-01-19
ATE14016T1 (de) 1985-07-15
AU557096B2 (en) 1986-12-04
NZ201000A (en) 1985-08-16
JPH0343273B2 (fr) 1991-07-01
PH19140A (en) 1986-01-10
IE53109B1 (en) 1988-06-22
JPS5823689A (ja) 1983-02-12

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