IL65598A - 1-(3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl)-4-hydroxy-4-phenylpiperidines,a process for their preparation and their use as medicaments - Google Patents

1-(3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl)-4-hydroxy-4-phenylpiperidines,a process for their preparation and their use as medicaments

Info

Publication number
IL65598A
IL65598A IL65598A IL6559882A IL65598A IL 65598 A IL65598 A IL 65598A IL 65598 A IL65598 A IL 65598A IL 6559882 A IL6559882 A IL 6559882A IL 65598 A IL65598 A IL 65598A
Authority
IL
Israel
Prior art keywords
phenylpiperidines
benzisoxazol
medicaments
fluoro
propyl
Prior art date
Application number
IL65598A
Other languages
English (en)
Other versions
IL65598A0 (en
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/366,247 external-priority patent/US4396770A/en
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of IL65598A0 publication Critical patent/IL65598A0/xx
Priority to IL75107A priority Critical patent/IL75107A0/xx
Publication of IL65598A publication Critical patent/IL65598A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/825—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups all hydroxy groups bound to the ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
IL65598A 1981-04-27 1982-04-25 1-(3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl)-4-hydroxy-4-phenylpiperidines,a process for their preparation and their use as medicaments IL65598A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL75107A IL75107A0 (en) 1981-04-27 1985-05-07 3-(ypsilon-chloropropyl)-6-fluoro-1,2-benzisoxazole,a process for its preparation and its use as intermediate

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25769881A 1981-04-27 1981-04-27
US06/366,247 US4396770A (en) 1982-04-09 1982-04-09 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines

Publications (2)

Publication Number Publication Date
IL65598A0 IL65598A0 (en) 1982-07-30
IL65598A true IL65598A (en) 1985-12-31

Family

ID=26946142

Family Applications (1)

Application Number Title Priority Date Filing Date
IL65598A IL65598A (en) 1981-04-27 1982-04-25 1-(3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl)-4-hydroxy-4-phenylpiperidines,a process for their preparation and their use as medicaments

Country Status (10)

Country Link
EP (2) EP0063799B1 (forum.php)
AU (1) AU564572B2 (forum.php)
DE (1) DE3267658D1 (forum.php)
DK (1) DK151019C (forum.php)
FI (1) FI821415L (forum.php)
GR (1) GR75417B (forum.php)
IL (1) IL65598A (forum.php)
NO (1) NO821361L (forum.php)
NZ (1) NZ200400A (forum.php)
PT (1) PT74799B (forum.php)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4420485A (en) * 1982-09-29 1983-12-13 Hoechst-Roussel Pharmaceuticals Inc. 1'-[3-(1,2-Benzisoxazol-3-yl) proply]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines]
FR2588860B1 (fr) * 1985-10-21 1988-08-12 Isochem Sa (chloro-3 propionyl)-2 fluoro-4 phenol, procede pour sa preparation, et application a la preparation de la fluoro-6 chromanone-4
US5114936A (en) * 1990-08-23 1992-05-19 Hoechst-Roussel Pharmaceuticals Incorporated 6,7-dihydro-3-phenyl-1,2-benzisoxazol-4(5h)-ones and -ols, compositions and pharmaceutical use
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6043064B2 (ja) * 1979-11-28 1985-09-26 ウェルファイド株式会社 新規イソオキサゾ−ル誘導体

Also Published As

Publication number Publication date
PT74799A (en) 1982-05-01
AU8300482A (en) 1982-11-04
IL65598A0 (en) 1982-07-30
DK151019B (da) 1987-10-12
GR75417B (forum.php) 1984-07-16
PT74799B (en) 1984-06-27
NZ200400A (en) 1987-04-30
EP0063799B1 (en) 1985-11-27
NO821361L (no) 1982-10-28
EP0063799A3 (en) 1982-12-15
AU564572B2 (en) 1987-08-20
DK151019C (da) 1988-03-14
FI821415A7 (fi) 1982-10-28
FI821415L (fi) 1982-10-28
FI821415A0 (fi) 1982-04-23
DK186182A (da) 1982-10-28
EP0149229B1 (en) 1989-06-14
EP0149229A2 (en) 1985-07-24
EP0063799A2 (en) 1982-11-03
EP0149229A3 (en) 1986-10-29
DE3267658D1 (en) 1986-01-09

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