IL60095A - Synergistic analgesic pharmaceutical compositions comprising nalbuphine and acetaminophen - Google Patents

Synergistic analgesic pharmaceutical compositions comprising nalbuphine and acetaminophen

Info

Publication number
IL60095A
IL60095A IL60095A IL6009580A IL60095A IL 60095 A IL60095 A IL 60095A IL 60095 A IL60095 A IL 60095A IL 6009580 A IL6009580 A IL 6009580A IL 60095 A IL60095 A IL 60095A
Authority
IL
Israel
Prior art keywords
nalbuphine
acetaminophen
pharmaceutical compositions
analgesic pharmaceutical
synergistic analgesic
Prior art date
Application number
IL60095A
Other languages
English (en)
Other versions
IL60095A0 (en
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of IL60095A0 publication Critical patent/IL60095A0/xx
Publication of IL60095A publication Critical patent/IL60095A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL60095A 1979-05-18 1980-05-16 Synergistic analgesic pharmaceutical compositions comprising nalbuphine and acetaminophen IL60095A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/040,281 US4237140A (en) 1979-05-18 1979-05-18 Analgesic mixture of nalbuphine and acetaminophen

Publications (2)

Publication Number Publication Date
IL60095A0 IL60095A0 (en) 1980-07-31
IL60095A true IL60095A (en) 1982-12-31

Family

ID=21910135

Family Applications (1)

Application Number Title Priority Date Filing Date
IL60095A IL60095A (en) 1979-05-18 1980-05-16 Synergistic analgesic pharmaceutical compositions comprising nalbuphine and acetaminophen

Country Status (12)

Country Link
US (1) US4237140A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0019282B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS55154917A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU529764B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1139671A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3061597D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU178867B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE49988B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL60095A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ193695A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH15265A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA802916B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322427A (en) * 1981-04-16 1982-03-30 Bristol-Myers Company Analgetic compositions and methods of use
US4366159A (en) * 1981-09-08 1982-12-28 Michael Richard Magruder Nalbuphine-narcotic analgesic composition and method of producing analgesia
US4404211A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and flurbiprofen
US4404208A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and tiflamizole
US4407805A (en) * 1982-06-30 1983-10-04 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and zomepirac
US4404210A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and ibuprofen
US4404209A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and sulindac
US4407804A (en) * 1982-06-30 1983-10-04 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and indomethacin
US4402962A (en) * 1982-06-30 1983-09-06 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and 4,5-bis(4-methoxyphenyl)-2-(trifluoromethylsulfonyl)-1H-imidazole
AU565634B2 (en) * 1982-06-30 1987-09-24 E.I. Du Pont De Nemours And Company Synergistic compositions of nalbuphine and non-narcotic analgesic compounds
US4656177A (en) * 1982-07-22 1987-04-07 Analgesic Associates Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
US4777174A (en) * 1982-07-22 1988-10-11 Analgesic Associates Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
ZA835324B (en) * 1982-07-22 1984-09-26 Abraham Sunshine Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
US4600579A (en) * 1983-06-07 1986-07-15 Mallinckrodt, Inc. N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same
US4722928A (en) * 1985-12-02 1988-02-02 E. I. Du Pont De Nemours And Company N-oxide prodrug derivatives of 3-hydroxy morphinans and partial morphinans having improved oral bioavailability, pharmaceutical compositions, and processes
DK0566709T5 (da) 1991-09-06 2009-05-18 Ortho Mcneil Janssen Pharm Præparat indeholdende et tramadolmateriale og acetaminophen og anvendelse deraf
US5558876A (en) * 1995-03-29 1996-09-24 Alcon Laboratories, Inc. Topical ophthalmic acidic drug formulations
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
US6375957B1 (en) 1997-12-22 2002-04-23 Euro-Celtique, S.A. Opioid agonist/opioid antagonist/acetaminophen combinations
ES2415876T3 (es) * 1997-12-22 2013-07-29 Euro-Celtique S.A. Forma de dosificación farmacéutica oral que comprende una combinación de un agonista de opiáceos y un antagonista de opiáceos
ATE431145T1 (de) 2000-02-08 2009-05-15 Euro Celtique Sa Missbrauchssichere orale opioid-agonist zubereitungen
EP1387673B1 (en) 2001-05-11 2010-12-29 Endo Pharmaceuticals Inc. Abuse-resistant controlled-release opioid dosage form
PT1416842E (pt) 2001-07-18 2009-03-31 Euro Celtique Sa Composições farmacêuticas de oxicodona e naloxona
RU2004106619A (ru) 2001-08-06 2005-07-10 Эро-Селтик С.А. (Lu) Композиции опиоидного агониста, содержащие высвобождаемый и изолированный антагонист
WO2003013433A2 (en) 2001-08-06 2003-02-20 Euro-Celtique S.A. Sequestered antagonist formulations
US20030044458A1 (en) 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
DK2425821T5 (en) 2002-04-05 2018-02-12 Mundipharma As Pharmaceutical preparation containing oxycodone and naloxone
WO2004026283A1 (en) 2002-09-20 2004-04-01 Alpharma, Inc. Sequestering subunit and related compositions and metohds
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
MY135852A (en) 2003-04-21 2008-07-31 Euro Celtique Sa Pharmaceutical products
EP1604666A1 (en) 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD)
EP1702558A1 (en) 2005-02-28 2006-09-20 Euro-Celtique S.A. Method and device for the assessment of bowel function
DK2402005T3 (da) 2005-08-24 2021-03-15 Endo Pharmaceuticals Inc Formuleringer med langvarig frigivelse af nalbuphin
US8394812B2 (en) 2005-08-24 2013-03-12 Penwest Pharmaceuticals Co. Sustained release formulations of nalbuphine
MX2008016372A (es) 2006-06-19 2009-05-28 Alpharma Inc Composiciones farmaceuticas.
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
AU2010223323B2 (en) 2009-03-10 2013-07-04 Euro-Celtique S.A. Immediate release pharmaceutical compositions comprising oxycodone and naloxone
US10071089B2 (en) 2013-07-23 2018-09-11 Euro-Celtique S.A. Combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
JP7009059B2 (ja) 2013-12-24 2022-02-10 ヴァージニア コモンウェルス ユニバーシティ 酸素化コレステロール硫酸塩（ｏｃｓ）の使用
JOP20190094A1 (ar) * 2016-10-27 2019-04-25 Broad Inst Inc مركبات 1، 2، 4-تريازولون تحمل ثلاثة بدائل عند المواقع 2، 4، 5 مفيدة كمثبطات لديهيدروجيناز ثنائي هيدرو أوروتات (dhodh)
WO2019070917A1 (en) * 2017-10-03 2019-04-11 The Schepens Eye Research Institute, Inc. COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE DEGENERATION OF RETINAL PIGMENT EPITHELIUM AND METHODS USING SAME
KR102700501B1 (ko) * 2018-09-03 2024-08-28 제이콥 바이오테크 엘티디 세바코일 디날부핀과 아세트아미노펜의 약학적 제제 및 통증 치료 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL26896A (en) * 1966-01-19 1970-11-30 Endo Lab 14 - Hydroxynormorphinins and 14 - Hydroxynormorphinones
US4029798A (en) * 1975-06-02 1977-06-14 Sumitomo Chemical Company, Limited Analgetic composition
JPS5946205B2 (ja) * 1976-01-01 1984-11-10 科研製薬株式会社 ベンゾイル誘導体を有効成分とする消炎鎮痛剤

Also Published As

Publication number Publication date
CA1139671A (en) 1983-01-18
ZA802916B (en) 1981-12-30
DE3061597D1 (en) 1983-02-17
EP0019282B1 (en) 1983-01-12
NZ193695A (en) 1984-05-31
AU529764B2 (en) 1983-06-16
US4237140A (en) 1980-12-02
PH15265A (en) 1982-11-02
HU178867B (en) 1982-07-28
JPH0144684B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-09-29
IL60095A0 (en) 1980-07-31
EP0019282A1 (en) 1980-11-26
AU5835180A (en) 1980-11-20
JPS55154917A (en) 1980-12-02
IE801019L (en) 1980-11-18
IE49988B1 (en) 1986-01-22

Similar Documents

Publication Publication Date Title
IL60095A (en) Synergistic analgesic pharmaceutical compositions comprising nalbuphine and acetaminophen
GB2103591B (en) Pharmaceutical compositions and process
DE3372705D1 (en) Pharmaceutical composition and its use
NZ194432A (en) Lipophilic muramyl-peptides and pharmaceutical compositions
PT76147A (en) Process for the preparation of pyrazolooxazines pyrazolothiazines and pyrazoloquinolines with a lipoxygenase inhibiting effect and their use for the preparation of pharmaceutical compositions having a lipoxygenase inhibiting effect
NZ194961A (en) Enkephalin analogues and pharmaceutical compositions
NZ193798A (en) 3-thiovinyl-cephalosporin derivatives and pharmaceutical compositions
NZ194584A (en) -lactam antibiotics and pharmaceutical compositions
NZ210105A (en) Oxazolidine derivatives and pharmaceutical compositions
IL60550A (en) Pharmaceutical compositions comprising aryl-pyrazolineamine derivatives and certain novel such compounds
PH16443A (en) Substituted tetraazetricyclic compounds and their pharmaceutical compositions
DE2964696D1 (en) N-(benzothienopyrazol)-amides and pharmaceutical compositions containing them
IL61700A (en) Analgesic tetrapeptides,their preparation and pharmaceutical compositions comprising them
IL61703A (en) Analgesic pentapeptides,their preparation and pharmaceutical compositions comprising them
IL61117A (en) 2beta-acetoxymethyl-penam compounds and pharmaceutical compositions containing them
GB2047534B (en) Analgesic and myotonolytic compositions
IL60376A (en) 3-diphenylmethyleneazetidines and pharmaceutical compositions containing them
IL61701A (en) Analgesic pentapeptides,their preparation and pharmaceutical compositions comprising them
GB2050833B (en) Pharmaceutical compositions and process for the preparation thereof
IL69058A0 (en) Synergistic pharmaceutical analgesic compositions
PH16220A (en) Pyrro-lidine derivatives and pharmaceutical compositions thereof
IL59177A0 (en) Spiro-quinolylhydantoins and pharmaceutical compositions containing them
NZ205732A (en) Thiatriazine derivatives and pharmaceutical compositions
NZ203649A (en) 2-beta-d-ribofuranosylselenazole-4-carboxamide derivatives and pharmaceutical compositions
PH19604A (en) Isoquinoline derivatives and pharmaceutical compositions containing the same