IL56892A0 - Novel prostacyclin analogs,process and intermediates for their manufacture and their use medicaments - Google Patents

Novel prostacyclin analogs,process and intermediates for their manufacture and their use medicaments

Info

Publication number
IL56892A0
IL56892A0 IL56892A IL5689279A IL56892A0 IL 56892 A0 IL56892 A0 IL 56892A0 IL 56892 A IL56892 A IL 56892A IL 5689279 A IL5689279 A IL 5689279A IL 56892 A0 IL56892 A0 IL 56892A0
Authority
IL
Israel
Prior art keywords
intermediates
manufacture
prostacyclin analogs
novel prostacyclin
use medicaments
Prior art date
Application number
IL56892A
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL56892A0 publication Critical patent/IL56892A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
IL56892A 1978-03-18 1979-03-15 Novel prostacyclin analogs,process and intermediates for their manufacture and their use medicaments IL56892A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782811950 DE2811950A1 (en) 1978-03-18 1978-03-18 NEW PROSTACYCLIN ANALOGS

Publications (1)

Publication Number Publication Date
IL56892A0 true IL56892A0 (en) 1979-05-31

Family

ID=6034863

Family Applications (1)

Application Number Title Priority Date Filing Date
IL56892A IL56892A0 (en) 1978-03-18 1979-03-15 Novel prostacyclin analogs,process and intermediates for their manufacture and their use medicaments

Country Status (7)

Country Link
EP (1) EP0004335A3 (en)
JP (1) JPS54130558A (en)
AU (1) AU4518279A (en)
DE (1) DE2811950A1 (en)
ES (1) ES478530A1 (en)
IL (1) IL56892A0 (en)
ZA (1) ZA791266B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH648556A5 (en) * 1981-03-11 1985-03-29 Hoffmann La Roche FLUORPROSTACYCLINE.
JPS6028943A (en) * 1983-07-26 1985-02-14 Sankyo Co Ltd Carbacyclin analog
KR20160048222A (en) 2007-12-17 2016-05-03 유나이티드 세러퓨틱스 코오포레이션 An improved process to prepare treprostinil, the active ingredient in remodulin®
CA2777070C (en) * 2010-06-03 2019-11-05 United Therapeutics Corporation Treprostinil production
WO2012118943A1 (en) 2011-03-02 2012-09-07 United Therapeutics Corporation Synthesis of intermediate for treprostinil production
WO2016064764A1 (en) 2014-10-20 2016-04-28 United Therapeutics Corporation Synthesis of intermediate for producing prostacyclin derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
GB1583961A (en) * 1976-05-11 1981-02-04 Wellcome Found Prostacyclin and derivatives thereof
CH629493A5 (en) * 1976-05-11 1982-04-30 Wellcome Found Processes for preparing novel prostaglandin derivatives
MX4813E (en) * 1976-06-01 1982-10-19 Upjohn Co PROCEDURE FOR PREPARING ANALOGS OF PROSTAGLANDINAS
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
IT1098350B (en) * 1977-07-28 1985-09-07 Upjohn Co PROSTAGLANDINIC DERIVATIVES
DE2743283A1 (en) * 1977-09-27 1979-04-05 Hoechst Ag NEW PROSTACYCLIN ANALOG

Also Published As

Publication number Publication date
AU4518279A (en) 1979-09-20
ZA791266B (en) 1980-03-26
EP0004335A3 (en) 1979-11-28
ES478530A1 (en) 1979-11-01
EP0004335A2 (en) 1979-10-03
DE2811950A1 (en) 1979-12-13
JPS54130558A (en) 1979-10-09

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