AU4518279A - Prostacyclin analogues - Google Patents

Prostacyclin analogues

Info

Publication number
AU4518279A
AU4518279A AU45182/79A AU4518279A AU4518279A AU 4518279 A AU4518279 A AU 4518279A AU 45182/79 A AU45182/79 A AU 45182/79A AU 4518279 A AU4518279 A AU 4518279A AU 4518279 A AU4518279 A AU 4518279A
Authority
AU
Australia
Prior art keywords
prostacyclin analogues
prostacyclin
analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU45182/79A
Inventor
Wilhelm Bartmann
Elmar Konz
Ulrich Lerch
Bernward Scholkens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU4518279A publication Critical patent/AU4518279A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
AU45182/79A 1978-03-18 1979-03-16 Prostacyclin analogues Abandoned AU4518279A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782811950 DE2811950A1 (en) 1978-03-18 1978-03-18 NEW PROSTACYCLIN ANALOGS
DE28119508 1978-03-18

Publications (1)

Publication Number Publication Date
AU4518279A true AU4518279A (en) 1979-09-20

Family

ID=6034863

Family Applications (1)

Application Number Title Priority Date Filing Date
AU45182/79A Abandoned AU4518279A (en) 1978-03-18 1979-03-16 Prostacyclin analogues

Country Status (7)

Country Link
EP (1) EP0004335A3 (en)
JP (1) JPS54130558A (en)
AU (1) AU4518279A (en)
DE (1) DE2811950A1 (en)
ES (1) ES478530A1 (en)
IL (1) IL56892A0 (en)
ZA (1) ZA791266B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH648556A5 (en) * 1981-03-11 1985-03-29 Hoffmann La Roche FLUORPROSTACYCLINE.
JPS6028943A (en) * 1983-07-26 1985-02-14 Sankyo Co Ltd Carbacyclin analog
KR20160048222A (en) 2007-12-17 2016-05-03 유나이티드 세러퓨틱스 코오포레이션 An improved process to prepare treprostinil, the active ingredient in remodulin®
WO2011153363A1 (en) 2010-06-03 2011-12-08 United Therapeutics Corporation Treprostinil production
CA2828958C (en) 2011-03-02 2015-11-03 United Therapeutics Corporation Synthesis of intermediate for treprostinil production
CN107108427A (en) 2014-10-20 2017-08-29 联合治疗学有限公司 For the synthesis for the intermediate for preparing prostacyclin derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
GB1583961A (en) * 1976-05-11 1981-02-04 Wellcome Found Prostacyclin and derivatives thereof
CH629493A5 (en) * 1976-05-11 1982-04-30 Wellcome Found Processes for preparing novel prostaglandin derivatives
MX4813E (en) * 1976-06-01 1982-10-19 Upjohn Co PROCEDURE FOR PREPARING ANALOGS OF PROSTAGLANDINAS
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
IT1098350B (en) * 1977-07-28 1985-09-07 Upjohn Co PROSTAGLANDINIC DERIVATIVES
DE2743283A1 (en) * 1977-09-27 1979-04-05 Hoechst Ag NEW PROSTACYCLIN ANALOG

Also Published As

Publication number Publication date
ZA791266B (en) 1980-03-26
DE2811950A1 (en) 1979-12-13
ES478530A1 (en) 1979-11-01
EP0004335A3 (en) 1979-11-28
JPS54130558A (en) 1979-10-09
IL56892A0 (en) 1979-05-31
EP0004335A2 (en) 1979-10-03

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