IL56021A - 2-heterocyclylalklyl-6-methoxy-naphathalenes,their preparation and pharmaceutical compositions containing them - Google Patents

2-heterocyclylalklyl-6-methoxy-naphathalenes,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL56021A
IL56021A IL56021A IL5602178A IL56021A IL 56021 A IL56021 A IL 56021A IL 56021 A IL56021 A IL 56021A IL 5602178 A IL5602178 A IL 5602178A IL 56021 A IL56021 A IL 56021A
Authority
IL
Israel
Prior art keywords
naphathalenes
heterocyclylalklyl
methoxy
preparation
pharmaceutical compositions
Prior art date
Application number
IL56021A
Other languages
English (en)
Other versions
IL56021A0 (en
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7735307A external-priority patent/FR2409994A1/fr
Priority claimed from FR7829413A external-priority patent/FR2439195A2/fr
Application filed by Synthelabo filed Critical Synthelabo
Publication of IL56021A0 publication Critical patent/IL56021A0/xx
Publication of IL56021A publication Critical patent/IL56021A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL56021A 1977-11-24 1978-11-22 2-heterocyclylalklyl-6-methoxy-naphathalenes,their preparation and pharmaceutical compositions containing them IL56021A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7735307A FR2409994A1 (fr) 1977-11-24 1977-11-24 Derives de naphtalene et leur application en therapeutique
FR7829413A FR2439195A2 (fr) 1978-10-16 1978-10-16 Derives du naphtalene et leur application en therapeutique

Publications (2)

Publication Number Publication Date
IL56021A0 IL56021A0 (en) 1979-01-31
IL56021A true IL56021A (en) 1981-09-13

Family

ID=26220312

Family Applications (1)

Application Number Title Priority Date Filing Date
IL56021A IL56021A (en) 1977-11-24 1978-11-22 2-heterocyclylalklyl-6-methoxy-naphathalenes,their preparation and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US4243665A (da)
EP (1) EP0002401B1 (da)
JP (1) JPS6039273B2 (da)
AR (1) AR225604A1 (da)
AU (1) AU517219B2 (da)
CA (1) CA1101858A (da)
DE (1) DE2860314D1 (da)
DK (1) DK519678A (da)
ES (1) ES475299A1 (da)
FI (1) FI783586A (da)
GR (1) GR65321B (da)
IE (1) IE47677B1 (da)
IL (1) IL56021A (da)
IT (1) IT1101422B (da)
NO (1) NO783933L (da)
NZ (1) NZ188982A (da)
PT (1) PT68821A (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4342759A (en) * 1980-08-19 1982-08-03 Synthelabo Antithrombotic method
US4997836A (en) * 1988-11-11 1991-03-05 Takeda Chemical Industries, Ltd. Trisubstituted piperazine compounds, their production and use
AUPP818099A0 (en) 1999-01-14 1999-02-11 Fujisawa Pharmaceutical Co., Ltd. New n-containing heterocyclic compounds
US8450353B2 (en) * 2007-12-21 2013-05-28 Avon Products, Inc. Topical compositions containing desthiobiotin and its derivatives and a method of treating skin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2119077A (en) * 1933-11-24 1938-05-31 Ostro Res Lab Inc Naphthalene derivatives containing a c h n group and process of producing them
US2724713A (en) * 1954-03-24 1955-11-22 American Cyanamid Co 1-carbobenzoxypiperazines and process of preparing same
US2858312A (en) * 1956-02-17 1958-10-28 Miles Lab Hypotensive agents
DE1189553B (de) * 1962-08-09 1965-03-25 Degussa Verfahren zur Herstellung von racemischen und optisch aktiven Piperazinderivaten
US3935214A (en) * 1968-07-26 1976-01-27 Donau-Pharmazie Gesellschaft M.B.H. 2-or 3 keto-3-or-2-phenyl-1,4-disubstituted piperazines
JPS50151885A (da) * 1974-05-29 1975-12-06
US4125612A (en) * 1977-06-20 1978-11-14 Schering Corporation N-1-(p-Biphenylalkyl)piperazines and their use as anti-inflammatory agents

Also Published As

Publication number Publication date
ES475299A1 (es) 1979-04-16
IE782313L (en) 1979-05-24
EP0002401B1 (fr) 1980-12-10
PT68821A (fr) 1978-12-01
IE47677B1 (en) 1984-05-16
GR65321B (en) 1980-08-11
AU4188478A (en) 1979-05-31
FI783586A (fi) 1979-05-25
DK519678A (da) 1979-05-25
CA1101858A (en) 1981-05-26
IL56021A0 (en) 1979-01-31
DE2860314D1 (en) 1981-02-19
IT7830063A0 (it) 1978-11-22
IT1101422B (it) 1985-09-28
EP0002401A1 (fr) 1979-06-13
JPS5481280A (en) 1979-06-28
NO783933L (no) 1979-05-28
AU517219B2 (en) 1981-07-16
NZ188982A (en) 1980-03-05
US4243665A (en) 1981-01-06
JPS6039273B2 (ja) 1985-09-05
AR225604A1 (es) 1982-04-15

Similar Documents

Publication Publication Date Title
IL54842A (en) 1-piperidino-phthalazine derivatives,their preparation and pharmaceutical compositions containing them
IL55183A0 (en) Novel imidazoquinazoline derivatives, their preparation and pharmaceutical compositions containing them
IL55643A (en) Cyclopeptides,their preparation and pharmaceutical compositions containing them
IL56017A (en) 5-cyano-prostacyclin derivatives,their manufacture and pharmaceutical compositions containing them
IL54337A (en) 1-aminoindanes, their preparation and pharmaceutical compositions comprising them
IL55765A (en) Dehydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL56248A (en) 4-spectinomycylamine and salts thereof,their preparation and pharmaceutical compositions containing them
IL54535A0 (en) Novel -lactam derivatives, their preparation and pharmaceutical compositions containing them
IL53857A0 (en) New aminoalkoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them
IL55654A0 (en) Novel propionamides,their preparation and pharmaceutical compositions containing them
IL55254A (en) Bis-isoquinolinium compounds,their preparation and pharmaceutical compositions containing them
IL54358A (en) 1-substituted-3-amino-6,7-dialkoxy-1h-1,2,4-benzothiadiazine-1-oxides,their preparation and pharmaceutical compositions containing them
IL55894A (en) 1-alkylenedithia (or oxathia) benzyl-4-heteroaryl-piperazine derivatives,their preparation and pharmaceutical compositions containing them
IL55857A (en) Benzodioxanylcarbonyl-piperazinoquinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL53766A0 (en) 4-diphenylmethylene-1-hydroxybenzyl-piperidine derivatives, their preparation and pharmaceutical compositions containing them
IL55018A (en) Benzylpyrimidines,their manufacture and pharmaceutical compositions containing them
IL53861A0 (en) Novel n-aralkylaniline derivatives, their preparation and pharmaceutical compositions containing them
IL54899A (en) Pyridazinylhydrazones,their preparation and pharmaceutical compositions containing them
IL55095A0 (en) Novel piperidino-propanol derivatives,their preparation and pharmaceutical compositions containing them
IL55120A0 (en) New 3-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL55352A0 (en) New 3-amino-17a-aza-d-homoandrostane derivatives, their preparation and pharmaceutical compositions containing them
IL53948A0 (en) New thiazinoindole derivatives, their preparation and pharmaceutical compositions containing them
IL54169A0 (en) Novel steroid spirooxazolidines, their preparation and pharmaceutical compositions containing them
IL56021A (en) 2-heterocyclylalklyl-6-methoxy-naphathalenes,their preparation and pharmaceutical compositions containing them
IL54121A0 (en) Novel aryl-hexafuranosides, their preparation and pharmaceutical compositions containing them