IL53639A - 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL53639A IL53639A IL53639A IL5363977A IL53639A IL 53639 A IL53639 A IL 53639A IL 53639 A IL53639 A IL 53639A IL 5363977 A IL5363977 A IL 5363977A IL 53639 A IL53639 A IL 53639A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- dihydropyridine derivatives
- dihydropyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762658183 DE2658183A1 (de) | 1976-12-22 | 1976-12-22 | In 2-position substituierte 1,4- dihydropyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL53639A0 IL53639A0 (en) | 1978-03-10 |
| IL53639A true IL53639A (en) | 1981-11-30 |
Family
ID=5996272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL53639A IL53639A (en) | 1976-12-22 | 1977-12-19 | 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4188395A (en, 2012) |
| JP (1) | JPS5379873A (en, 2012) |
| AT (1) | AT361477B (en, 2012) |
| AU (1) | AU516921B2 (en, 2012) |
| BE (1) | BE862107A (en, 2012) |
| CA (1) | CA1105934A (en, 2012) |
| CH (1) | CH635323A5 (en, 2012) |
| DE (1) | DE2658183A1 (en, 2012) |
| DK (1) | DK571677A (en, 2012) |
| ES (1) | ES465290A1 (en, 2012) |
| FI (1) | FI773867A7 (en, 2012) |
| FR (1) | FR2378763A1 (en, 2012) |
| GB (1) | GB1560280A (en, 2012) |
| IL (1) | IL53639A (en, 2012) |
| NL (1) | NL7714074A (en, 2012) |
| SE (1) | SE7714607L (en, 2012) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4307103A (en) * | 1978-09-08 | 1981-12-22 | Fujisawa Pharmaceutical Co., Ltd. | Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same |
| CA1117117A (en) * | 1978-10-10 | 1982-01-26 | Fujisawa Pharmaceutical Co., Ltd. | 2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same |
| NZ193167A (en) * | 1979-03-27 | 1984-08-24 | Boots Co Plc | Quinoline derivatives and pharmaceutical compositions |
| YU42386B (en) * | 1981-03-13 | 1988-08-31 | Krka | Process for preparing 1,4-dihydro-pyridine derivatives |
| CS228917B2 (en) | 1981-03-14 | 1984-05-14 | Pfizer | Method of preparing substituted derivatives of 1,4-dihydropyridine |
| JPS57175166A (en) | 1981-04-23 | 1982-10-28 | Banyu Pharmaceut Co Ltd | Carbamoyloxyalkyl-1,4-dihydropyridine derivative and its preparation |
| DE3207982A1 (de) * | 1982-03-05 | 1983-09-08 | Bayer Ag, 5090 Leverkusen | Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln |
| DE3363743D1 (en) * | 1982-07-22 | 1986-07-03 | Pfizer Ltd | Dihydropyridine anti-ischaemic and antihypertensive agents |
| HU192166B (en) * | 1982-08-06 | 1987-05-28 | Banyu Pharma Co Ltd | Process for producing 2-carbamoyl-oxy-alkyl-1,4-dihydro-pyridine derivatives |
| PH19166A (en) * | 1982-09-04 | 1986-01-16 | Pfizer | Dihydropyridined,pharmaceutical compositions and method of use |
| EP0107293A3 (en) * | 1982-09-04 | 1984-06-06 | Pfizer Limited | Dihydropyridines |
| US4572908A (en) * | 1982-12-21 | 1986-02-25 | Pfizer Inc. | Dihydropyridines |
| US4515799A (en) * | 1983-02-02 | 1985-05-07 | Pfizer Inc. | Dihydropyridine anti-ischaemic and antihypertensive agents |
| FI852359L (fi) * | 1984-06-27 | 1985-12-28 | Hoffmann La Roche | Dihydropyridinderivat. |
| GB8421039D0 (en) * | 1984-08-17 | 1984-09-19 | Wyeth John & Brother Ltd | Heterocyclic compounds |
| GR851819B (en, 2012) * | 1984-08-17 | 1985-11-26 | Wyeth John & Brother Ltd | |
| US4833150A (en) * | 1985-03-14 | 1989-05-23 | Nelson Research & Development Co. | 1,4-dihydropyridines |
| CA1267416A (en) * | 1985-06-17 | 1990-04-03 | Ila Sircar | 1,4-dihydropyridine derivatives useful for the treatment of cardiovascular disorders |
| IT1215299B (it) * | 1985-08-06 | 1990-01-31 | Boehringer Biochemia Srl | Diidropiridine 2-tiosostituite, metodo per la loro preparazione e composizione farmaceutiche che le contengono. |
| HU199796B (en) * | 1985-08-06 | 1990-03-28 | Boehringer Biochemia Srl | Process for producing 2-thiomethyl-substituted-1,4-dihydropyridines and pharmaceutical compositions comprising such compounds |
| IT1215298B (it) * | 1985-08-06 | 1990-01-31 | Boehringer Biochemia Srl | 2-(eteroalchil)-1,4-diidropiridine ed un processo per la loro produzione. |
| GB8526411D0 (en) * | 1985-10-25 | 1985-11-27 | Pfizer Ltd | Dihydropyridines |
| DE3544211A1 (de) * | 1985-12-13 | 1987-06-19 | Bayer Ag | Neue, fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| GB8531625D0 (en) * | 1985-12-23 | 1986-02-05 | Shell Int Research | Complex-forming polymers |
| US4849436A (en) * | 1986-03-11 | 1989-07-18 | Nelson Research & Development Co. | 1,4-dihydropyridines |
| IT1197012B (it) * | 1986-07-29 | 1988-11-25 | Boehringer Biochemia Srl | 2-(aciltio) metil diidropiridine, un processo per la loro preparazione e composizioni farmaceutiche che le contengono |
| US4983740A (en) * | 1986-08-04 | 1991-01-08 | Adir Et Compagnie | Process for 1,4-dihydropyridine compounds |
| FR2602231B1 (fr) * | 1986-08-04 | 1988-10-28 | Adir | Nouveaux derives de la dihydro-1,4 pyridine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| MX9701245A (es) * | 1996-02-19 | 1998-04-30 | Pfizer | Compuestos de 1,4 dihidropiridina. |
| US6653481B2 (en) * | 2000-12-29 | 2003-11-25 | Synthon Bv | Process for making amlodipine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1670827C3 (de) * | 1967-03-20 | 1974-10-24 | Bayer Ag, 5090 Leverkusen | 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin |
| US3883543A (en) * | 1969-05-10 | 1975-05-13 | Bayer Ag | N-alkyl-1,4-dihydropyridines |
| DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
| US3974278A (en) * | 1973-07-12 | 1976-08-10 | Bayer Aktiengesellschaft | 1,4-Dihydropyridine esters |
| GB1552911A (en) * | 1975-07-02 | 1979-09-19 | Fujisawa Pharmaceutical Co | 1,4 dihydropyridine derivatives and the preparation thereof |
-
1976
- 1976-12-22 DE DE19762658183 patent/DE2658183A1/de not_active Withdrawn
-
1977
- 1977-12-01 US US05/856,559 patent/US4188395A/en not_active Expired - Lifetime
- 1977-12-19 AU AU31708/77A patent/AU516921B2/en not_active Expired
- 1977-12-19 NL NL7714074A patent/NL7714074A/xx not_active Application Discontinuation
- 1977-12-19 IL IL53639A patent/IL53639A/xx unknown
- 1977-12-19 GB GB52668/77A patent/GB1560280A/en not_active Expired
- 1977-12-20 CH CH1568777A patent/CH635323A5/de not_active IP Right Cessation
- 1977-12-20 JP JP15248477A patent/JPS5379873A/ja active Granted
- 1977-12-20 FI FI773867A patent/FI773867A7/fi not_active Application Discontinuation
- 1977-12-20 AT AT912977A patent/AT361477B/de not_active IP Right Cessation
- 1977-12-21 ES ES465290A patent/ES465290A1/es not_active Expired
- 1977-12-21 FR FR7738602A patent/FR2378763A1/fr active Granted
- 1977-12-21 SE SE7714607A patent/SE7714607L/xx not_active Application Discontinuation
- 1977-12-21 CA CA293,648A patent/CA1105934A/en not_active Expired
- 1977-12-21 BE BE183669A patent/BE862107A/xx unknown
- 1977-12-21 DK DK571677A patent/DK571677A/da unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7714074A (nl) | 1978-06-26 |
| AT361477B (de) | 1981-03-10 |
| JPS6131100B2 (en, 2012) | 1986-07-17 |
| GB1560280A (en) | 1980-02-06 |
| CA1105934A (en) | 1981-07-28 |
| AU516921B2 (en) | 1981-07-02 |
| IL53639A0 (en) | 1978-03-10 |
| FR2378763A1 (fr) | 1978-08-25 |
| BE862107A (fr) | 1978-06-21 |
| FI773867A7 (fi) | 1978-06-23 |
| FR2378763B1 (en, 2012) | 1980-09-19 |
| JPS5379873A (en) | 1978-07-14 |
| AU3170877A (en) | 1979-06-28 |
| DK571677A (da) | 1978-06-23 |
| SE7714607L (sv) | 1978-06-23 |
| CH635323A5 (de) | 1983-03-31 |
| ATA912977A (de) | 1980-08-15 |
| US4188395A (en) | 1980-02-12 |
| DE2658183A1 (de) | 1978-07-06 |
| ES465290A1 (es) | 1978-09-16 |
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