IL53350A - 4,5-disubstituted imidazole-2-thiones and their use as intermediates for preparing pharmaceutically active compounds - Google Patents

4,5-disubstituted imidazole-2-thiones and their use as intermediates for preparing pharmaceutically active compounds

Info

Publication number
IL53350A
IL53350A IL53350A IL5335077A IL53350A IL 53350 A IL53350 A IL 53350A IL 53350 A IL53350 A IL 53350A IL 5335077 A IL5335077 A IL 5335077A IL 53350 A IL53350 A IL 53350A
Authority
IL
Israel
Prior art keywords
thiones
intermediates
active compounds
pharmaceutically active
preparing pharmaceutically
Prior art date
Application number
IL53350A
Other languages
English (en)
Other versions
IL53350A0 (en
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of IL53350A0 publication Critical patent/IL53350A0/xx
Publication of IL53350A publication Critical patent/IL53350A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36—One oxygen atom
    • C07D263/42—One oxygen atom attached in position 5

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL53350A 1976-12-22 1977-11-10 4,5-disubstituted imidazole-2-thiones and their use as intermediates for preparing pharmaceutically active compounds IL53350A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB53538/76A GB1596376A (en) 1976-12-22 1976-12-22 4,5-disubstituted imidazole-2-thiones processes for their preparation and their use as intermediates

Publications (2)

Publication Number Publication Date
IL53350A0 IL53350A0 (en) 1978-01-31
IL53350A true IL53350A (en) 1981-10-30

Family

ID=10468162

Family Applications (1)

Application Number Title Priority Date Filing Date
IL53350A IL53350A (en) 1976-12-22 1977-11-10 4,5-disubstituted imidazole-2-thiones and their use as intermediates for preparing pharmaceutically active compounds

Country Status (21)

Country Link
US (1) US4166184A (xx)
JP (1) JPS5379863A (xx)
AU (1) AU514770B2 (xx)
BE (1) BE862095A (xx)
CA (1) CA1096388A (xx)
DE (1) DE2755749A1 (xx)
DK (1) DK559877A (xx)
ES (1) ES465346A1 (xx)
FI (1) FI773592A (xx)
FR (1) FR2375219A1 (xx)
GB (1) GB1596376A (xx)
HU (1) HU177745B (xx)
IE (1) IE46493B1 (xx)
IL (1) IL53350A (xx)
LU (1) LU78725A1 (xx)
NL (1) NL7714261A (xx)
NO (1) NO774407L (xx)
PH (1) PH14357A (xx)
PT (1) PT67276B (xx)
SE (1) SE7714123L (xx)
ZA (1) ZA776538B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0170872B1 (de) * 1984-07-13 1989-08-23 Bayer Ag Verfahren zur Herstellung, von 3,7-Bisacetaminoheptanon-2
EP0428849A3 (en) * 1989-09-28 1991-07-31 Hoechst Aktiengesellschaft Retroviral protease inhibitors
US7767826B2 (en) * 2007-10-05 2010-08-03 Pharmatech International, Inc. Process for the synthesis of L-(+)-ergothioneine
CN109956881A (zh) * 2017-12-26 2019-07-02 上海凯赛生物技术研发中心有限公司 一种苯甲酰戊二胺及其制备和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2585388A (en) * 1948-11-17 1952-02-12 Lilly Co Eli Preparation of 2-mercaptoimidazoles
GB1054708A (xx) * 1964-10-02

Also Published As

Publication number Publication date
LU78725A1 (xx) 1978-04-17
GB1596376A (en) 1981-08-26
FR2375219A1 (fr) 1978-07-21
IE46493B1 (en) 1983-06-29
BE862095A (fr) 1978-06-21
PT67276B (en) 1979-04-18
IL53350A0 (en) 1978-01-31
ZA776538B (en) 1978-08-30
ES465346A1 (es) 1978-09-16
FI773592A (fi) 1978-06-23
US4166184A (en) 1979-08-28
PT67276A (en) 1977-12-01
JPS5379863A (en) 1978-07-14
HU177745B (en) 1981-12-28
CA1096388A (en) 1981-02-24
SE7714123L (sv) 1978-06-23
DK559877A (da) 1978-06-23
FR2375219B1 (xx) 1981-02-27
DE2755749A1 (de) 1978-06-29
AU514770B2 (en) 1981-02-26
NO774407L (no) 1978-06-23
IE46493L (en) 1978-06-22
AU3157277A (en) 1979-06-21
NL7714261A (nl) 1978-06-26
PH14357A (en) 1981-06-03

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