IL50643A - 12-aza-11/oxo-9,9-dimethyl-15-hydroxy-prostanoic acid analogues their preparation and pharmaceutical compositions containing them - Google Patents
12-aza-11/oxo-9,9-dimethyl-15-hydroxy-prostanoic acid analogues their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL50643A IL50643A IL50643A IL5064376A IL50643A IL 50643 A IL50643 A IL 50643A IL 50643 A IL50643 A IL 50643A IL 5064376 A IL5064376 A IL 5064376A IL 50643 A IL50643 A IL 50643A
- Authority
- IL
- Israel
- Prior art keywords
- aza
- oxo
- hydroxy
- dimethyl
- preparation
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB43989/75A GB1560942A (en) | 1975-10-25 | 1975-10-25 | 10,10,-dimethyl-12-azaprostaglandins |
| GB2127976 | 1976-05-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL50643A0 IL50643A0 (en) | 1976-12-31 |
| IL50643A true IL50643A (en) | 1980-02-29 |
Family
ID=26255242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL50643A IL50643A (en) | 1975-10-25 | 1976-10-08 | 12-aza-11/oxo-9,9-dimethyl-15-hydroxy-prostanoic acid analogues their preparation and pharmaceutical compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4136190A (xx) |
| JP (1) | JPS5253856A (xx) |
| AT (1) | AT364820B (xx) |
| AU (1) | AU506442B2 (xx) |
| CA (1) | CA1068716A (xx) |
| DE (1) | DE2647968A1 (xx) |
| DK (1) | DK479076A (xx) |
| ES (2) | ES452648A1 (xx) |
| FI (1) | FI762999A (xx) |
| FR (1) | FR2328465A1 (xx) |
| HU (1) | HU174538B (xx) |
| IE (1) | IE44299B1 (xx) |
| IL (1) | IL50643A (xx) |
| NL (1) | NL7611760A (xx) |
| NO (1) | NO763566L (xx) |
| NZ (1) | NZ182263A (xx) |
| SE (1) | SE417091B (xx) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1524818A (en) * | 1974-11-29 | 1978-09-13 | Beecham Group Ltd | 12-azaprostaglandins |
| US4187312A (en) * | 1975-10-25 | 1980-02-05 | Beecham Group Limited | 3-Hydroxy-4,4-dimethyl-5-pyrrolidone derivatives |
| NZ182264A (en) * | 1975-10-25 | 1979-01-11 | Beecham Group Ltd | 2-carboxyalkyl-1-hydroxyalkyl-pyrrolidin-3,5-dione or-piperidin-3,6-dione derivatives prarmaceutical compostions |
| IL58384A0 (en) * | 1978-10-14 | 1980-01-31 | Beecham Group Ltd | 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them |
| DE3212591A1 (de) * | 1982-04-03 | 1983-10-13 | Gödecke AG, 1000 Berlin | 2-pyrrolin-3-carbonitril-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3975399A (en) * | 1974-08-06 | 1976-08-17 | E. I. Du Pont De Nemours And Company | 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones |
| US4003911A (en) * | 1975-09-26 | 1977-01-18 | E. I. Du Pont De Nemours And Company | Selected 3-pyrrolidinones and 2,4-pyrrolidindiones |
-
1976
- 1976-10-07 NZ NZ182263A patent/NZ182263A/xx unknown
- 1976-10-08 IL IL50643A patent/IL50643A/xx unknown
- 1976-10-14 AU AU18687/76A patent/AU506442B2/en not_active Expired
- 1976-10-15 US US05/732,989 patent/US4136190A/en not_active Expired - Lifetime
- 1976-10-19 NO NO763566A patent/NO763566L/no unknown
- 1976-10-20 FI FI762999A patent/FI762999A/fi not_active Application Discontinuation
- 1976-10-20 FR FR7631526A patent/FR2328465A1/fr active Granted
- 1976-10-22 HU HU76BE1276A patent/HU174538B/hu unknown
- 1976-10-22 SE SE7611774A patent/SE417091B/xx unknown
- 1976-10-22 DE DE19762647968 patent/DE2647968A1/de not_active Withdrawn
- 1976-10-22 DK DK479076A patent/DK479076A/da not_active Application Discontinuation
- 1976-10-22 NL NL7611760A patent/NL7611760A/xx unknown
- 1976-10-22 CA CA263,954A patent/CA1068716A/en not_active Expired
- 1976-10-22 AT AT0788676A patent/AT364820B/de not_active IP Right Cessation
- 1976-10-22 IE IE2329/76A patent/IE44299B1/en unknown
- 1976-10-22 ES ES452648A patent/ES452648A1/es not_active Expired
- 1976-10-23 JP JP51127730A patent/JPS5253856A/ja active Pending
-
1977
- 1977-10-01 ES ES462849A patent/ES462849A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT364820B (de) | 1981-11-25 |
| DK479076A (da) | 1977-04-26 |
| HU174538B (hu) | 1980-02-28 |
| FR2328465B1 (xx) | 1978-11-17 |
| AU506442B2 (en) | 1980-01-03 |
| ES462849A1 (es) | 1978-06-01 |
| ATA788676A (de) | 1981-04-15 |
| NL7611760A (nl) | 1977-04-27 |
| SE7611774L (sv) | 1977-04-26 |
| US4136190A (en) | 1979-01-23 |
| CA1068716A (en) | 1979-12-25 |
| NO763566L (xx) | 1977-04-26 |
| IE44299B1 (en) | 1981-10-07 |
| AU1868776A (en) | 1978-04-20 |
| FR2328465A1 (fr) | 1977-05-20 |
| FI762999A (xx) | 1977-04-26 |
| SE417091B (sv) | 1981-02-23 |
| IE44299L (en) | 1977-04-25 |
| NZ182263A (en) | 1979-01-11 |
| DE2647968A1 (de) | 1977-05-05 |
| ES452648A1 (es) | 1978-03-16 |
| IL50643A0 (en) | 1976-12-31 |
| JPS5253856A (en) | 1977-04-30 |
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