IL45644A - 3-alkyl-1,9-dihydroxyhexa-hydrodibenzo(b,d)pyran derivatives - Google Patents

3-alkyl-1,9-dihydroxyhexa-hydrodibenzo(b,d)pyran derivatives

Info

Publication number
IL45644A
IL45644A IL45644A IL4564474A IL45644A IL 45644 A IL45644 A IL 45644A IL 45644 A IL45644 A IL 45644A IL 4564474 A IL4564474 A IL 4564474A IL 45644 A IL45644 A IL 45644A
Authority
IL
Israel
Prior art keywords
hydrodibenzo
dihydroxyhexa
alkyl
pyran derivatives
pyran
Prior art date
Application number
IL45644A
Other languages
English (en)
Other versions
IL45644A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL45644A0 publication Critical patent/IL45644A0/xx
Publication of IL45644A publication Critical patent/IL45644A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
IL45644A 1973-11-05 1974-09-11 3-alkyl-1,9-dihydroxyhexa-hydrodibenzo(b,d)pyran derivatives IL45644A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/413,010 US3968125A (en) 1973-11-05 1973-11-05 Dihydroxyhexahydrodibenzo[b,d]pyrans

Publications (2)

Publication Number Publication Date
IL45644A0 IL45644A0 (en) 1974-11-29
IL45644A true IL45644A (en) 1978-03-10

Family

ID=23635420

Family Applications (1)

Application Number Title Priority Date Filing Date
IL45644A IL45644A (en) 1973-11-05 1974-09-11 3-alkyl-1,9-dihydroxyhexa-hydrodibenzo(b,d)pyran derivatives

Country Status (26)

Country Link
US (1) US3968125A (enExample)
JP (1) JPS6033835B2 (enExample)
AR (1) AR202318A1 (enExample)
AT (1) AT336012B (enExample)
BE (1) BE821716A (enExample)
BG (1) BG26387A3 (enExample)
CA (1) CA1023753A (enExample)
CH (1) CH605894A5 (enExample)
CS (1) CS193507B2 (enExample)
DD (1) DD116230A5 (enExample)
DE (1) DE2451934C2 (enExample)
DK (1) DK136719B (enExample)
ES (1) ES431674A1 (enExample)
FR (1) FR2249664B1 (enExample)
GB (1) GB1487637A (enExample)
HU (1) HU169193B (enExample)
IE (1) IE40023B1 (enExample)
IL (1) IL45644A (enExample)
NL (1) NL7414439A (enExample)
PH (1) PH11788A (enExample)
PL (2) PL95748B1 (enExample)
RO (1) RO71766A (enExample)
SE (1) SE415762B (enExample)
SU (1) SU524517A3 (enExample)
YU (1) YU36515B (enExample)
ZA (1) ZA745751B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1522057A (en) * 1975-11-03 1978-08-23 Pfizer 9-hydroxydibenzo(b,d)pyrans and intermediates therefor
US4051152A (en) * 1976-01-07 1977-09-27 Sharps Associates Oxo C-ring benzopyrans
US4087546A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiasthmatic drugs
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
US4054581A (en) * 1976-07-06 1977-10-18 Eli Lilly And Company Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor
US4209520A (en) * 1977-06-17 1980-06-24 Pfizer Inc. Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents
US4133819A (en) * 1977-06-17 1979-01-09 Pfizer Inc. Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents
US4243674A (en) * 1978-06-12 1981-01-06 Pfizer Inc. 9-Hydroxydibenzo[b,d]pyrans and intermediates therefore
US4454144A (en) * 1982-06-21 1984-06-12 Pfizer Inc. Substituted dibenzo[b,d]pyran analgesics
JPS6299930U (enExample) * 1985-12-12 1987-06-25
US8449908B2 (en) * 2000-12-22 2013-05-28 Alltranz, Llc Transdermal delivery of cannabidiol
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
PT1477186E (pt) 2002-02-19 2010-02-11 Shionogi & Co Antipruriginosos
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
CN101594878A (zh) 2006-09-18 2009-12-02 雷普特药品公司 通过给予受体相关蛋白(rap)-缀合物对肝病症的治疗
PT2176208E (pt) * 2007-07-30 2015-05-11 Zynerba Pharmaceuticals Inc Pró-fármacos de canabidiol, composições compreendendo pró- fármacos de canabidiol e métodos de utilização dos mesmos
WO2009099670A2 (en) * 2008-02-08 2009-08-13 Nektar Therapeutics Al, Corporation Oligomer-cannabinoid conjugates
US20090247619A1 (en) * 2008-03-06 2009-10-01 University Of Kentucky Cannabinoid-Containing Compositions and Methods for Their Use
DK3395372T3 (da) 2009-02-20 2022-04-19 Enhanx Biopharm Inc System til afgivelse af glutathion-baseret medikament
CN110075069A (zh) 2009-05-06 2019-08-02 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN110996926A (zh) 2017-07-20 2020-04-10 耶路撒冷希伯来大学伊萨姆研究开发有限公司 用于将亲脂性化合物递送进入和/或穿过皮肤的药物膜组合物
EP3681474B1 (en) 2017-09-11 2025-10-29 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Compositions and methods for nasal administration of drugs to brain and for systemic effect
CA3116187A1 (en) 2017-11-29 2019-06-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Cannabinoids compositions and methods
CA3116194A1 (en) 2018-11-04 2020-05-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Orally administrable cannabinoids-containing compositions and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507885A (en) * 1966-03-25 1970-04-21 Hoffmann La Roche 3-alkyl-6h-dibenzo(b,d)pyrans
US3636058A (en) * 1966-03-25 1972-01-18 Hoffmann La Roche 7 10 - dihydro - 3 - alkyl - 6h - dibenzo(b d) pyran-6 9(8h)-diones and 5-hydroxy-7-alkyl-4-chromanones
CH558792A (de) * 1971-10-14 1975-02-14 Petrzilka Theodor Verfahren zur herstellung von tetrahydrodibenzopyranen.

Also Published As

Publication number Publication date
CS193507B2 (en) 1979-10-31
JPS6033835B2 (ja) 1985-08-05
YU36515B (en) 1984-02-29
DK136719C (enExample) 1978-04-24
PL93908B1 (enExample) 1977-07-30
JPS5071678A (enExample) 1975-06-13
IE40023L (en) 1975-05-05
US3968125A (en) 1976-07-06
DE2451934A1 (de) 1975-05-07
FR2249664A1 (enExample) 1975-05-30
AT336012B (de) 1977-04-12
SE415762B (sv) 1980-10-27
PL95748B1 (pl) 1977-11-30
NL7414439A (nl) 1975-05-07
PH11788A (en) 1978-07-05
HU169193B (enExample) 1976-10-28
AU7321274A (en) 1976-03-18
AR202318A1 (es) 1975-05-30
FR2249664B1 (enExample) 1978-03-24
CA1023753A (en) 1978-01-03
DD116230A5 (enExample) 1975-11-12
BE821716A (fr) 1975-04-30
IE40023B1 (en) 1979-02-28
IL45644A0 (en) 1974-11-29
RO71766A (ro) 1982-12-06
GB1487637A (en) 1977-10-05
DE2451934C2 (de) 1983-10-06
DK573274A (enExample) 1975-07-07
SU524517A3 (ru) 1976-08-05
BG26387A3 (bg) 1979-03-15
SE7413833L (enExample) 1975-05-06
ZA745751B (en) 1976-04-28
ATA886374A (de) 1976-08-15
ES431674A1 (es) 1976-11-16
DK136719B (da) 1977-11-14
YU265874A (en) 1982-02-25
CH605894A5 (enExample) 1978-10-13

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