IL44203A - Apparatus for non-surgical reversible sterilization of females - Google Patents
Apparatus for non-surgical reversible sterilization of femalesInfo
- Publication number
- IL44203A IL44203A IL44203A IL4420374A IL44203A IL 44203 A IL44203 A IL 44203A IL 44203 A IL44203 A IL 44203A IL 4420374 A IL4420374 A IL 4420374A IL 44203 A IL44203 A IL 44203A
- Authority
- IL
- Israel
- Prior art keywords
- oviduct
- tip
- terminal end
- block
- self
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/20—Vas deferens occluders; Fallopian occluders
- A61F6/22—Vas deferens occluders; Fallopian occluders implantable in tubes
- A61F6/225—Vas deferens occluders; Fallopian occluders implantable in tubes transcervical
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Reproductive Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
Abstract
A method and apparatus is provided for non-surgical reversible sterilization of females. In the method of this invention an apparatus to which a removable tip is attached is inserted into the uterus. The tip is aligned with the uterine end of the oviduct. A curable elastomeric composition is injected, through an aperture in the tip, into the oviduct in an amount sufficient to fill the portion of the oviduct adjacent to the uterus. The elastomeric composition is allowed to solidify and adhere to the above noted tip. The apparatus is then removed with the tip being ejected from the apparatus so as to remain adhered to the resulting oviduct block. The above procedure is repeated for the opposite oviduct. The resulting oviduct blocks prevent the passage of ovum from the ovaries to the uterus and sperm from entering the oviduct thereby preventing conception. The oviduct blocks if desired can be removed non-surgically by utilizing an apparatus which grips the tip portion of the oviduct block and extracts the entire oviduct block from the oviduct.
[US3805767A]
Description
•METHOD AND APPARATUS FOR NON-SURGICAL,REVERSIBLE STERILIZATION OP FEMALES ppj HS*B9- *?w π'πιτ>κ n'XT' ^noo ipnsrv-raw METHOD AND APPARATUS FOR NON-SURGICAL, REVERSIBLE STERILIZATION OF FEMALES A tfOBSaitxa&xasatSi apparatus is provided for non-surgical Accordiig^o reversible sterilization of females. S^%lVEX«i)S^3S ¾$ this invention an apparatus to which a removable tip is attached is inserted into the uterus. The tip is aligned with the uterine end of the oviduct. A curable elastomeric composition is injected, through an aperture in the tip, into the oviduct in an amount sufficient to fill the portion of the oviduct adjacent to the uterus. The tip is larger in diameter than the uterine end of the oviduct and substantially seals the end thereof during the filling of the end portion of the oviduct with the liquid elastomeric composition. The elastomeric composition is allowed to solidify and adhere to the tip to form the oviduct block. The apparatus is then removed with the tip being ejected from the apparatus so as to remain adhered to and part of the resulting oviduct block. The above procedure is repeated for the opposite oviduct. The resulting oviduct blocks prevent the passage of ovum from the ovaries to the uterus and sperm from entering the oviduct thereby preventing conception. The oviduct blocks if desired can be removed non-surgically by utilizing an apparatus which grips the larger tip portion of the oviduct block within the uterus and extracts the entire oviduct block from the oviduct.
This invention is concerned with a method and apparatus for nonsurgical , reversible sterilization of females.
One' of the more pressing problems which is encountered in the World today is that of over population. The problem of ^ over population which has been a substantial problem for a consi- 1 derable period of time in certain highly populated areas, such as Asia and the Indian Sub-Continent is now becoming a problem in less populated areas of the World such as Europe and the Americas. Over population results in such long range problems as pollution, famine and even war.
Birth control has been relied on as the principal means to control over population. In the field of birth control the prevention of conception is considerably more acceptable for controlling population growth than abortion. However, the methods heretofore suggested for contraception have had certain inherent problems which limited the applicability and effectiveness .
The ideal contraception method should be 100% effective in preventing conception; should not rely on willpower; should not interfere with the satisfaction of sexual relationships, and should be low in cost taking into consideration the effective life of the contraceptive method. In addition the contraceptive method must not have any harmful psychological side effects. An extremely important feature of an ideal contraceptive method especially for family planning is that it be reversible so that it will be possible to have additional children if desired.
The most common methods of contraception which are currently employed on a mass scale each have certain inherent deficiencies which limit their usefulness. The use of such techniques and devices such as rhythm, withdrawal, condoms and diaphragms and vaginal foams all have been found to be highly unreliable. The more recently promoted methods such as intrauterine devices and use of contraceptive pills likewise have certain defects which limit their effectiveness. The intrauterine devices cannot be utilized by all females and there is some indication that they cause irritation and discomfort and are often rejected by females. The contraceptive pill cannot be utilized by many females due to incompatability with their normal hormone balance. Furthermore, the use of the pill- has been found to increase the risks of certain carcigenic conditions There are currently two methods in wide use which are generally considered to be effective contraceptive methods.
These are oviduct ligation for females and vasectomy for males.
In both these methods the ducts from the reproductive organs are severed and accordingly the contraceptive technique if properly performed and if there is no natural regeneration is 100% effective. However, both methods have the defect that it is difficult, if not impossible, to reverse the procedure so as to restore the normal reproductive capacity.
It has been well established by gynecologists that a primary cause of infertility in females is blockage of the oviducts from the ovary to the uterus . The ovum when discharged from the ovaries is absorbed by the body and is prevented from coming in contact with the sperm and accordingly conception not does /occur. Females having this natural condition normally do not even realize it exists and do not suffer any adverse side effects besides being infertile. Having been made aware of this natural condition those skilled in the art have suggested artificial blocking of the oviduct to impart sterility.
It was reported by Corfman et al in Obstetrics and Gynecology Vol. 27 No. 6 pages 880-883 (June 1966) that various substances could be injected transcervically into the oviducts. * Hefnawi et al. Amr. J. Obst & Gynec , Vol. 99, No. 3 pages 421-427 (October 1, 1967) reported attempts to block the cases and 2 negative cases. Further, in order to remove the oviduct blocks it was necessary to conduct a laparotomy.
In accordance with this invention n mp hnr3 nn r n pnrnfni is provided to form oviduct blocks which prevent conception when in place and which can be non-surgically removed if desired. The apparatus is inserted through the cervix into the uterus. The tip on the apparatus is then aligned with the uterine end of the oviduct. A mixture of a fluid elastomeric material and a catalyst for polymerizing the elastomeric mixture is injected through an aperture in the tip of the oviduct. The elastomeric material is allowed to solidify and to adhere to the tip. The tip is released so that it remains with the injected elastomeric material to form the oviduct block of this invention. The apparatus is then removed.
The oviduct block can be removed non-surgically by inserting an instrument into the uterus through the cervix which grips the tip of the oviduct block. The oviduct block is then withdrawn to restore normal fertility.
Fig. 1 is an illustration in partial cross-section of an apparatus especially adopted for use in the method of this invention.
Fig. 2 is an illustration in partial cross-section of a uterus, the cervix and a portion of the vagina. The uterus is illustrated with an oviduct block insert in one of the oviduct and the terminal end of the apparatus of Fig. 1 positioned for jnsertion of an oviduct block into the opposite oviduct.
Fig. 3 is an enlarged illustration taken in partial cross-section of the terminal end of the apparatus of Fig. 1. - the separation of the tip from the apparatus of Fig. 1. · t applying In &&g KSXK8&x$£ this invention an oviduct block is formed in situ in the oviduct. The oviduct block is more preferable formed from a medical inert plastic which has approximately the same modulus of elasticity as the oviduct. The selection of material having the proper modulus of elasticity appears to both expulsion prevent ac-pdnsa-io-K of the oviduct block and substantially eliminates any physical discomfort. The materials which have been found most useful in the method of this invention are the commercially available medical grade silicone elastomers. The uncured silicone elastomer in the fluid state is blended with a catalyst for solidifying the elastomer and a dilution fluid to control the viscosity during injection and also to control the modulus of elasticity of the cured solidified material. It is preferable to also include a radiopaque material in the mixture to facilitate the placement of the oviduct block and to facilitate removal of the oviduct block if desired.
A tip 10 is molded from an inert plastic material to which the injected elastomeric material will adhere on solidification. In this regard it should be noted that silicone-rubber is ideally suited for this purpose when a silicone elastomer is used for formation of the oviduct block.
As . shown in the drawing the portion of the tip 10 which will be in contact with uterine end of the oviduct 12 has a sperical configuration. The tip is larger in diameter than the uterine end of the oviduct and seals the lumen or end opening thereof during the filling of the end portion of the oviduct with the liquid elastomeric composition. The tip 10 has an aperture 14 which extends throughout the entire length of the tip 1Q . In preferably a thread of a material which is inert in uterine fluids, such as nylon or polyester.
The apparatus 20 shown in Fig. 1 is specifically designed for use in the method of this invention. The apparatus 20 includes a tubular extension 22, a dispensing apparatus 24, and a control handle 26 both for operating, the dispensing means and for positioning the tip 10 on the end of the tubular extension 22.
The tubular extension 22 has a rigid section 26 which is adjacent to the control handle. The opposite terminal end portion 28 on which the tip 10 is secured is flexible. One end of each control wire 30 or 32 is attached to the end portion of the flexible section 28. The control wires 30 and 32 are connected at their opposite ends to a part of separately controlled drums 34 (only one drum is shown) mounted on the control hand 26. By adjustment of the drums 34 to either collect or release the wires 30 or 32 the position of the tip 10 can be adjusted and bent in a curved configuration as shown in Fig. 2.
At the flexible terminal end 28 a metal connector 36 is provided which has annular piston ring 38 which mates with the piston rings 16 on the tip 10. The metal connector 36 further has defined in it a constricted area having a sharp cut off portion 4 A tube 42 extends from the dispensing means 24, through the tubular extension 22 to the aperture 14 in the tip 10.
The dispensing means 24 consists of a mixing syringe 44 in which the plunger 46 is adapted to provide mixing of a fluid elastomeric material, a catalyst and other additive as may be required The syringe 44 is mounted on top of the control handle 26 with the plunger 46 in contact with a rack 48 and a pivotal mounted pawl 5^0. The pawl 50 is connected to a trigger 52. Squeezing the trigger 52 causes the plunger 46 to be advanced within the syringe 44 and material within the syringe 44 to be dispensed through the tube The tip 10 being premolded of a silicone rubber is somewhat p elastic and deforms somewhat until the piston ring 16 of the ^ tip 10 engages and locks with the mating piston rings 38.
The tubular extension 2% with tip 10 installed is inserted into the vagina 54, through the cervix 56 into the fluoroscopic uterine cavity 58. Then, preferably using techniques, the tip 10 is aligned with the uterine end of one of the oviducts 12. It should be noted that because of the shape of the uterine cavity 58 the tip can be guided blindly into the proper position. The relative position of the flexible end 28 is controlled by adjustment of the drums 34.
Once the tip 10 is in position, the flu¾ mixture of the elastomer, catalyst and other additives are injected through the tube 42 to the tip 10 by operation of the trigger 52 as noted above. The uncured fluid elastomeric composition 60 flows through the aperture 14 in the tip 10 and then into the oviduct 12. A sufficient amount of the mixture is injected to fill approximately on third or more of the length of the oviduct 12. Some of the material will flow back around the tip 10 so that the surface of the tip 10 will conform to the shape of the uterine end of the oviduct 12 as shown by the portion 62 in Fig. 5.
The injected elastomeric material 60 is allowed to cure and solidify. The cured material will adhere to the tip 10 to make essentially an oviduct block having a preformed larger tip in a single unit. 42 Once the elastomeric material has cured, the tube 4¾ and 28 the terminal end $Sxare withdrawn within the tubular extension 22.
The edge 40 cuts the cured material which remains in the tube 42 rrom the cured material in the aperture 14 of the tip 10. Continued 28 withdrawal of the terminal end ¾-€ results in the tip 10 being strippe from the terminal end as shown in phantom in Fig.5. solidify in the oviducts. The elastomeric material was thinned prior to injection so as to have a relatively fluid mixture for injection. The reported results obtained with rabbits was quite unsatisfactory. The incidence of pregnancy after insertion of the oviduct blocks was quite high. Effective sterilization was only achieved if the plug was placed in the medial portion of the oviduct. To remove the plug it was necessary to conduct laparotomy. A further problem which was reported was the tendency for the plug to migrate from the oviduct into either the uterine cavity or even more dangerously into the peritoneal cavity.
Rakshit reported in the Calcutta Med J 65, No. 3 (March, 1968) attempts to use various materials to block the oviducts to prevent conception. It was suggested to use a plastic material of a nature which solidifies after being mixed with a catalyst to form the oviduct blocks. Rakshit specifically taught however that because of high viscosity the silicone rubbers could not be injected transvaginally and laparotomies were conducted to inject the material directly into the uterus. The material was then allowed to flow into oviducts. It was suggested in this article by Rakshit that it may be possible to introduce a plastic material transcervically into the uterus and then to allow it to flow in the oviducts. Using this method however the resulting oviduct blocks would have to be removed surgically to reestablish fertility.
Rakshit further reported in Human Sterilization, edited by Ralph Rechart (1971) pages 213-221 the technique of attempting to form oviduct blocks by inserting a cannula directly into the uterus through the cervix and filling the uterus with a curable liquid silicone plastic. The injected silicone plastic was allowed to flow into the oviducts and cure in place to form the which conforms to the interior of the oviduct in which it is J* cast, thus effectively preventing conception. ^ The oviduct block can remain in place until it is desired to remove it. The use of a material having approximately the same modulus of elasticity as the oviducts assists in maintaining the oviduct blocks 64 in position. The natural convolution of the oviduct likewise results in stabilization of the oviduct blocks 64. The tip 10 serves a most important function of preventing the oviduct block 64 from migrating into the cavity, a problem that was a serious and relatively common problem with other similar prior art technique.
As noted above the oviduct block is inserted non-surgically. The method is relatively simple to learn by those skilled in the medical art. The time required is likewise quite short with a skilled person being able to block both oviducts in about 15 to 30 minutes.
As noted above the oviduct block can be removed non-surgically if desired. An instrument of the type shown in Fig. 1 is used for this purpose. The tip 10 is replaced with a hooked member which is adapted to engage the loop 18. Once the loop 18 is engaged the oviduct block 64 is withdrawn. It is also possible to use a pronged member to grip the tip and then pull out the oviduct block.
Both the insertion and removal of the oviduct block 64 are relatively painless. However a local anesthetic can be used is desired.
The effectiveness of the contraception method of this invention was found to be excellent. On rabbit tests it was found that the method is 100% effective if the oviduct blocks are properly placed. In further rabbit tests it was found that after the oviduct blocks were removed that fertility was restored. There examination have not indicated that there is any adverse reaction to the tissue of the oviducts .
The apparatus of this invention has been described in the preferred embodiment. It should be appreciated that various modifications can be made to the apparatus without department from the scope of this invention. For example, the control handle 26 has been provided to enable a simple one handed operation of the apparatus. It is possible, however, to simply use control wires which are operated by the fingers of the hand rather than the drums. Further, the dispensing apparatus consisting of the trigger 52, rack 48 and pawl 50, could likewise be removed and the syringe operated manually. Furthermore, the configuration of the tip 10 can be modified to a different shape or such as a conical configuration *£ other suitable shapes and still be satisfactory for use in this invention. These and other modifications which would be obvious to those skilled in the art are included within the scope of the subjoined claims.
Claims (10)
1. An apparatus for inserting an oviduct block, wherein a self-curing elastomer is injected into the oviduct in liquid condition and is solidified in situ, and wherein the injection is performed by means of a tip detachable connected with an inserting member for introducing the tip into the cervix and placing it in an axial position with respect to the oviduct, characterised in that the tip is made of a solid synthetic material adapted to attach itself to the injected material when the same solidifies, and that the tip has such a shape that it fits in a sealing contact in the end of tho ovlduet adjacent to the uterus, the diameter of the tip being slightly larger than the internal diameter •f the oviduct, the inserting member being provided with a channel for injecting the liquid elastomer, and means being provided to detach the tip from the inserting member after the injection, so that it remains attached to the cured mass in the oviduct, in such manner that the block may be removed by drawing the cured mass from the oviduct by means of the tip*
2. An apparatus according to Claim 1, wherein said tip member further includes a loop member whereby said loop member can be gripped to non-surgieally remove said oviduct block*
3. * An apparatus according to Claim 1 wherein said self-curing elastomeric material is a self-curing silicone elastomer*
4. * An apparatus according to Claim 1 wherein said self- curing elastomeric material when solidified has a modulus of elasticity substantially the same as said oviduct*
5. · An apparatus according to any of the preceding claims wherein the tip member has am aperture. ΛρρΐΛ¼*03/2
6. An apparatus for forming the oviduct block according to claim 1, said apparatus comprising: a tubular means of a _ length sufficient to extend from vagina area of said female to the uterine ends of said oviducts and having a diameter sufficiently small to pass through the cervix of said female; said tubular means having first and second terminal ends; said first terminal end having an apertured tip member detaehably connected thereto and also means for releasably holding and ejecting said tip member, said tubular member including means for positioning said first terminal end with said tip member thereon adjacent the uterine end of said oviduct, and said t tubular member further including means for transmission of said self curing olastomeric material from a point adjacent to the second terminal end to and through said aperture in said tip member secured to the first terminal end.
7. » An apparatus of claim 6 in which the first terminal end portion is flexible*
8. · An apparatus according to claim 6 in which the position of the first terminal end is controlled by means operable fram the second terminal end*
9. · An apparatus according to claim 6 wherein the means for holding and ejecting said tip member comprises a slideable member positioned within said tubular member whereby when a tip member is secured at the first terminal end to said slideable member and said slideable member is drawn through said tubular member toward the second terminal end, said tip is removed from said sideable member*
10. The apparatus according to claim 6 wherein the dispensing mean* Is a syringe having a barrel and a plunger and wherein the plunger la advaneeable within the barrel by a rack and pawl drive operated from the second terminal end*
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00335816A US3805767A (en) | 1973-02-26 | 1973-02-26 | Method and apparatus for non-surgical, reversible sterilization of females |
Publications (2)
Publication Number | Publication Date |
---|---|
IL44203A0 IL44203A0 (en) | 1974-05-16 |
IL44203A true IL44203A (en) | 1977-03-31 |
Family
ID=23313333
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL44203A IL44203A (en) | 1973-02-26 | 1974-02-14 | Apparatus for non-surgical reversible sterilization of females |
Country Status (14)
Country | Link |
---|---|
US (1) | US3805767A (en) |
JP (1) | JPS5239595B2 (en) |
AU (1) | AU465515B2 (en) |
BE (1) | BE811539A (en) |
BR (1) | BR7401387D0 (en) |
CA (1) | CA1046372A (en) |
CH (1) | CH578876A5 (en) |
FR (1) | FR2218907B1 (en) |
GB (1) | GB1430045A (en) |
IL (1) | IL44203A (en) |
IT (1) | IT1015818B (en) |
NL (1) | NL154660B (en) |
SE (1) | SE419698B (en) |
ZA (1) | ZA74931B (en) |
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Publication number | Priority date | Publication date | Assignee | Title |
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US3042030A (en) * | 1958-11-25 | 1962-07-03 | Read Thane | Spherical type insert plug for body passageway and tool therefor |
US3182662A (en) * | 1962-07-25 | 1965-05-11 | Vithal N Shirodkar | Plastic prosthesis useful in gynaecological surgery |
US3422813A (en) * | 1965-06-21 | 1969-01-21 | Dow Corning | Method for sterilization of males |
US3707146A (en) * | 1967-03-07 | 1972-12-26 | Prod Res & Chem Corp | Means to inject a plastic into a cavity to produce a replica thereof |
US3680542A (en) * | 1970-05-11 | 1972-08-01 | Hugo S Cimber | Device for occlusion of an oviduct |
US3648683A (en) * | 1970-06-29 | 1972-03-14 | Nathan Brodie | Reversible intra-vas device |
-
1973
- 1973-02-26 US US00335816A patent/US3805767A/en not_active Expired - Lifetime
-
1974
- 1974-02-12 ZA ZA740931A patent/ZA74931B/en unknown
- 1974-02-14 IL IL44203A patent/IL44203A/en unknown
- 1974-02-22 SE SE7402428A patent/SE419698B/en not_active IP Right Cessation
- 1974-02-22 BR BR741387A patent/BR7401387D0/en unknown
- 1974-02-22 GB GB825174A patent/GB1430045A/en not_active Expired
- 1974-02-25 CA CA193,336A patent/CA1046372A/en not_active Expired
- 1974-02-25 FR FR7406289A patent/FR2218907B1/fr not_active Expired
- 1974-02-25 IT IT48696/74A patent/IT1015818B/en active
- 1974-02-25 NL NL747402502A patent/NL154660B/en not_active IP Right Cessation
- 1974-02-25 JP JP49022743A patent/JPS5239595B2/ja not_active Expired
- 1974-02-25 BE BE141359A patent/BE811539A/en unknown
- 1974-02-26 AU AU66031/74A patent/AU465515B2/en not_active Expired
- 1974-02-26 CH CH270874A patent/CH578876A5/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US3805767A (en) | 1974-04-23 |
JPS5239595B2 (en) | 1977-10-06 |
DE2407652B2 (en) | 1976-01-15 |
NL7402502A (en) | 1974-08-28 |
DE2407652A1 (en) | 1974-09-12 |
SE419698B (en) | 1981-08-24 |
JPS49135486A (en) | 1974-12-26 |
BR7401387D0 (en) | 1974-11-05 |
FR2218907B1 (en) | 1978-07-21 |
CH578876A5 (en) | 1976-08-31 |
IT1015818B (en) | 1977-05-20 |
IL44203A0 (en) | 1974-05-16 |
NL154660B (en) | 1977-10-17 |
AU6603174A (en) | 1975-08-28 |
GB1430045A (en) | 1976-03-31 |
BE811539A (en) | 1974-06-17 |
AU465515B2 (en) | 1975-10-02 |
ZA74931B (en) | 1974-12-24 |
CA1046372A (en) | 1979-01-16 |
FR2218907A1 (en) | 1974-09-20 |
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