IL43722A - 2-aminomethyleneindanones and pharmaceutical compositions containing them - Google Patents
2-aminomethyleneindanones and pharmaceutical compositions containing themInfo
- Publication number
- IL43722A IL43722A IL43722A IL4372273A IL43722A IL 43722 A IL43722 A IL 43722A IL 43722 A IL43722 A IL 43722A IL 4372273 A IL4372273 A IL 4372273A IL 43722 A IL43722 A IL 43722A
- Authority
- IL
- Israel
- Prior art keywords
- hydrogen
- compound
- chloro
- aminomethyleneindanones
- pharmaceutical compositions
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims 2
- HJOUSWJOPKLCGA-UHFFFAOYSA-N 2-(aminomethylidene)-3h-inden-1-one Chemical class C1=CC=C2C(=O)C(=CN)CC2=C1 HJOUSWJOPKLCGA-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 16
- 239000001257 hydrogen Substances 0.000 claims 16
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 14
- 150000001875 compounds Chemical class 0.000 claims 13
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 125000001309 chloro group Chemical group Cl* 0.000 claims 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 4
- 125000001153 fluoro group Chemical group F* 0.000 claims 3
- MZAGXDHQGXUDDX-JSRXJHBZSA-N (e,2z)-4-ethyl-2-hydroxyimino-5-nitrohex-3-enamide Chemical compound [O-][N+](=O)C(C)C(/CC)=C/C(=N/O)/C(N)=O MZAGXDHQGXUDDX-JSRXJHBZSA-N 0.000 claims 2
- 150000002431 hydrogen Chemical group 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
- C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- C07C225/18—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings the carbon skeleton containing also rings other than six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/312,693 US4022836A (en) | 1972-12-06 | 1972-12-06 | 2-Aminomethyleneindanone analgesic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL43722A0 IL43722A0 (en) | 1974-03-14 |
| IL43722A true IL43722A (en) | 1976-03-31 |
Family
ID=23212586
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL43722A IL43722A (en) | 1972-12-06 | 1973-11-29 | 2-aminomethyleneindanones and pharmaceutical compositions containing them |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US4022836A (no) |
| JP (1) | JPS5542066B2 (no) |
| AR (1) | AR207946A1 (no) |
| AT (1) | AT326646B (no) |
| BE (1) | BE808275A (no) |
| CA (1) | CA1002068A (no) |
| CH (1) | CH584677A5 (no) |
| DE (1) | DE2360096C2 (no) |
| DK (1) | DK139575B (no) |
| ES (1) | ES421167A1 (no) |
| FR (1) | FR2209565B1 (no) |
| GB (1) | GB1448026A (no) |
| IE (1) | IE38553B1 (no) |
| IL (1) | IL43722A (no) |
| LU (1) | LU68950A1 (no) |
| NL (1) | NL172057C (no) |
| NO (1) | NO137858C (no) |
| PH (1) | PH10690A (no) |
| SE (1) | SE405851B (no) |
| ZA (1) | ZA739052B (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4117012A (en) * | 1972-12-06 | 1978-09-26 | Pfizer Inc. | 2-aminomethyleneindanone analgesic agents |
| US4164514A (en) * | 1972-12-06 | 1979-08-14 | Pfizer Inc. | 2-Aminomethyleneindanone analgesic agents |
| US4334085A (en) * | 1978-09-14 | 1982-06-08 | Standard Oil Company (Indiana) | Transamination process for Mannich products |
| NZ209534A (en) * | 1983-09-30 | 1987-01-23 | Surgikos Inc | Antimicrobial fabric for surgical drape |
| US6369289B1 (en) | 2000-07-07 | 2002-04-09 | Tyco Healthcare Group Lp | Method and manufacture of a wound dressing for covering an open wound |
| DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
| EP1889198B1 (en) | 2005-04-28 | 2014-11-26 | Proteus Digital Health, Inc. | Pharma-informatics system |
| WO2008036682A2 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| DK3395372T3 (da) | 2009-02-20 | 2022-04-19 | Enhanx Biopharm Inc | System til afgivelse af glutathion-baseret medikament |
| EP2427178B1 (en) | 2009-05-06 | 2023-01-04 | Laboratory Skin Care, Inc. | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3454565A (en) * | 1966-10-05 | 1969-07-08 | American Cyanamid Co | Novel indanones |
-
1972
- 1972-12-06 US US05/312,693 patent/US4022836A/en not_active Expired - Lifetime
-
1973
- 1973-01-01 AR AR251362A patent/AR207946A1/es active
- 1973-11-26 GB GB5483073A patent/GB1448026A/en not_active Expired
- 1973-11-28 ZA ZA739052A patent/ZA739052B/xx unknown
- 1973-11-29 IE IE2160/73A patent/IE38553B1/xx unknown
- 1973-11-29 IL IL43722A patent/IL43722A/en unknown
- 1973-12-03 DE DE2360096A patent/DE2360096C2/de not_active Expired
- 1973-12-03 CA CA187,227A patent/CA1002068A/en not_active Expired
- 1973-12-04 FR FR7343232A patent/FR2209565B1/fr not_active Expired
- 1973-12-04 AT AT1013873A patent/AT326646B/de not_active IP Right Cessation
- 1973-12-05 CH CH1704473A patent/CH584677A5/xx not_active IP Right Cessation
- 1973-12-05 PH PH15292A patent/PH10690A/en unknown
- 1973-12-05 NO NO4652/73A patent/NO137858C/no unknown
- 1973-12-05 ES ES421167A patent/ES421167A1/es not_active Expired
- 1973-12-05 SE SE7316447A patent/SE405851B/xx unknown
- 1973-12-05 DK DK657173AA patent/DK139575B/da unknown
- 1973-12-05 NL NLAANVRAGE7316663,A patent/NL172057C/xx not_active IP Right Cessation
- 1973-12-06 JP JP13575773A patent/JPS5542066B2/ja not_active Expired
- 1973-12-06 BE BE1005561A patent/BE808275A/xx unknown
- 1973-12-06 LU LU68950A patent/LU68950A1/xx unknown
-
1977
- 1977-01-27 US US05/763,241 patent/US4064272A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NL172057B (nl) | 1983-02-01 |
| NL7316663A (no) | 1974-06-10 |
| FR2209565B1 (no) | 1977-04-08 |
| IE38553L (en) | 1974-06-06 |
| SE7316447L (no) | 1974-06-07 |
| AR207946A1 (es) | 1976-11-22 |
| IL43722A0 (en) | 1974-03-14 |
| CH584677A5 (no) | 1977-02-15 |
| ATA1013873A (de) | 1975-03-15 |
| DE2360096C2 (de) | 1982-07-01 |
| LU68950A1 (no) | 1974-07-05 |
| PH10690A (en) | 1977-08-10 |
| JPS5542066B2 (no) | 1980-10-28 |
| DE2360096A1 (de) | 1974-07-04 |
| US4064272A (en) | 1977-12-20 |
| BE808275A (fr) | 1974-06-06 |
| NL172057C (nl) | 1983-07-01 |
| CA1002068A (en) | 1976-12-21 |
| ZA739052B (en) | 1974-10-30 |
| NO137858C (no) | 1978-05-10 |
| NO137858B (no) | 1978-01-30 |
| DK139575C (no) | 1979-08-27 |
| AT326646B (de) | 1975-12-29 |
| IE38553B1 (en) | 1978-04-12 |
| SE405851B (sv) | 1979-01-08 |
| GB1448026A (en) | 1976-09-02 |
| US4022836A (en) | 1977-05-10 |
| FR2209565A1 (no) | 1974-07-05 |
| DK139575B (da) | 1979-03-12 |
| ES421167A1 (es) | 1976-04-01 |
| AU6302373A (en) | 1975-05-29 |
| JPS4986352A (no) | 1974-08-19 |
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