IL43722A - 2-aminomethyleneindanones and pharmaceutical compositions containing them - Google Patents
2-aminomethyleneindanones and pharmaceutical compositions containing themInfo
- Publication number
- IL43722A IL43722A IL43722A IL4372273A IL43722A IL 43722 A IL43722 A IL 43722A IL 43722 A IL43722 A IL 43722A IL 4372273 A IL4372273 A IL 4372273A IL 43722 A IL43722 A IL 43722A
- Authority
- IL
- Israel
- Prior art keywords
- hydrogen
- compound
- chloro
- aminomethyleneindanones
- pharmaceutical compositions
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims 2
- HJOUSWJOPKLCGA-UHFFFAOYSA-N 2-(aminomethylidene)-3h-inden-1-one Chemical class C1=CC=C2C(=O)C(=CN)CC2=C1 HJOUSWJOPKLCGA-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 16
- 239000001257 hydrogen Substances 0.000 claims 16
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 14
- 150000001875 compounds Chemical class 0.000 claims 13
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 125000001309 chloro group Chemical group Cl* 0.000 claims 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 4
- 125000001153 fluoro group Chemical group F* 0.000 claims 3
- MZAGXDHQGXUDDX-JSRXJHBZSA-N (e,2z)-4-ethyl-2-hydroxyimino-5-nitrohex-3-enamide Chemical compound [O-][N+](=O)C(C)C(/CC)=C/C(=N/O)/C(N)=O MZAGXDHQGXUDDX-JSRXJHBZSA-N 0.000 claims 2
- 150000002431 hydrogen Chemical group 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
- C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- C07C225/18—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings the carbon skeleton containing also rings other than six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/312,693 US4022836A (en) | 1972-12-06 | 1972-12-06 | 2-Aminomethyleneindanone analgesic agents |
Publications (2)
Publication Number | Publication Date |
---|---|
IL43722A0 IL43722A0 (en) | 1974-03-14 |
IL43722A true IL43722A (en) | 1976-03-31 |
Family
ID=23212586
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL43722A IL43722A (en) | 1972-12-06 | 1973-11-29 | 2-aminomethyleneindanones and pharmaceutical compositions containing them |
Country Status (20)
Country | Link |
---|---|
US (2) | US4022836A (ja) |
JP (1) | JPS5542066B2 (ja) |
AR (1) | AR207946A1 (ja) |
AT (1) | AT326646B (ja) |
BE (1) | BE808275A (ja) |
CA (1) | CA1002068A (ja) |
CH (1) | CH584677A5 (ja) |
DE (1) | DE2360096C2 (ja) |
DK (1) | DK139575B (ja) |
ES (1) | ES421167A1 (ja) |
FR (1) | FR2209565B1 (ja) |
GB (1) | GB1448026A (ja) |
IE (1) | IE38553B1 (ja) |
IL (1) | IL43722A (ja) |
LU (1) | LU68950A1 (ja) |
NL (1) | NL172057C (ja) |
NO (1) | NO137858C (ja) |
PH (1) | PH10690A (ja) |
SE (1) | SE405851B (ja) |
ZA (1) | ZA739052B (ja) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4117012A (en) * | 1972-12-06 | 1978-09-26 | Pfizer Inc. | 2-aminomethyleneindanone analgesic agents |
US4164514A (en) * | 1972-12-06 | 1979-08-14 | Pfizer Inc. | 2-Aminomethyleneindanone analgesic agents |
US4334085A (en) * | 1978-09-14 | 1982-06-08 | Standard Oil Company (Indiana) | Transamination process for Mannich products |
NZ209534A (en) * | 1983-09-30 | 1987-01-23 | Surgikos Inc | Antimicrobial fabric for surgical drape |
US6369289B1 (en) | 2000-07-07 | 2002-04-09 | Tyco Healthcare Group Lp | Method and manufacture of a wound dressing for covering an open wound |
ATE445838T1 (de) | 2001-07-25 | 2009-10-15 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
EP2671508B1 (en) | 2005-04-28 | 2020-09-16 | Proteus Digital Health, Inc. | Pharma-informatics system |
CA2663377A1 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
HUE059078T2 (hu) | 2009-02-20 | 2022-10-28 | Enhanx Biopharm Inc | Glutation-alapú hatóanyagszállító rendszer |
JP2012526144A (ja) | 2009-05-06 | 2012-10-25 | ラボラトリー スキン ケア インコーポレイテッド | 活性物質−リン酸カルシウム粒子複合体を含む経皮送達組成物およびその使用方法 |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3454565A (en) * | 1966-10-05 | 1969-07-08 | American Cyanamid Co | Novel indanones |
-
1972
- 1972-12-06 US US05/312,693 patent/US4022836A/en not_active Expired - Lifetime
-
1973
- 1973-01-01 AR AR251362A patent/AR207946A1/es active
- 1973-11-26 GB GB5483073A patent/GB1448026A/en not_active Expired
- 1973-11-28 ZA ZA739052A patent/ZA739052B/xx unknown
- 1973-11-29 IL IL43722A patent/IL43722A/en unknown
- 1973-11-29 IE IE2160/73A patent/IE38553B1/xx unknown
- 1973-12-03 DE DE2360096A patent/DE2360096C2/de not_active Expired
- 1973-12-03 CA CA187,227A patent/CA1002068A/en not_active Expired
- 1973-12-04 FR FR7343232A patent/FR2209565B1/fr not_active Expired
- 1973-12-04 AT AT1013873A patent/AT326646B/de not_active IP Right Cessation
- 1973-12-05 ES ES421167A patent/ES421167A1/es not_active Expired
- 1973-12-05 DK DK657173AA patent/DK139575B/da unknown
- 1973-12-05 SE SE7316447A patent/SE405851B/xx unknown
- 1973-12-05 NL NLAANVRAGE7316663,A patent/NL172057C/xx not_active IP Right Cessation
- 1973-12-05 PH PH15292A patent/PH10690A/en unknown
- 1973-12-05 NO NO4652/73A patent/NO137858C/no unknown
- 1973-12-05 CH CH1704473A patent/CH584677A5/xx not_active IP Right Cessation
- 1973-12-06 BE BE1005561A patent/BE808275A/xx unknown
- 1973-12-06 LU LU68950A patent/LU68950A1/xx unknown
- 1973-12-06 JP JP13575773A patent/JPS5542066B2/ja not_active Expired
-
1977
- 1977-01-27 US US05/763,241 patent/US4064272A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU6302373A (en) | 1975-05-29 |
NL172057C (nl) | 1983-07-01 |
IE38553B1 (en) | 1978-04-12 |
LU68950A1 (ja) | 1974-07-05 |
JPS5542066B2 (ja) | 1980-10-28 |
IE38553L (en) | 1974-06-06 |
DE2360096C2 (de) | 1982-07-01 |
AT326646B (de) | 1975-12-29 |
NO137858C (no) | 1978-05-10 |
ATA1013873A (de) | 1975-03-15 |
JPS4986352A (ja) | 1974-08-19 |
FR2209565B1 (ja) | 1977-04-08 |
US4022836A (en) | 1977-05-10 |
NL7316663A (ja) | 1974-06-10 |
PH10690A (en) | 1977-08-10 |
BE808275A (fr) | 1974-06-06 |
ES421167A1 (es) | 1976-04-01 |
US4064272A (en) | 1977-12-20 |
NO137858B (no) | 1978-01-30 |
CH584677A5 (ja) | 1977-02-15 |
FR2209565A1 (ja) | 1974-07-05 |
DE2360096A1 (de) | 1974-07-04 |
SE405851B (sv) | 1979-01-08 |
IL43722A0 (en) | 1974-03-14 |
GB1448026A (en) | 1976-09-02 |
ZA739052B (en) | 1974-10-30 |
DK139575C (ja) | 1979-08-27 |
SE7316447L (ja) | 1974-06-07 |
DK139575B (da) | 1979-03-12 |
NL172057B (nl) | 1983-02-01 |
AR207946A1 (es) | 1976-11-22 |
CA1002068A (en) | 1976-12-21 |
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