IL42976A - 1-(3-phenoxy-2-hydroxy-1-propyl)piperidine derivatives,their manufacture and pharmaceutical compositions containing them - Google Patents
1-(3-phenoxy-2-hydroxy-1-propyl)piperidine derivatives,their manufacture and pharmaceutical compositions containing themInfo
- Publication number
- IL42976A IL42976A IL42976A IL4297673A IL42976A IL 42976 A IL42976 A IL 42976A IL 42976 A IL42976 A IL 42976A IL 4297673 A IL4297673 A IL 4297673A IL 42976 A IL42976 A IL 42976A
- Authority
- IL
- Israel
- Prior art keywords
- dioxide
- benzothiadiazine
- dihydro
- chloro
- sulphamyl
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims 2
- QPMPQYGUAKDGAE-UHFFFAOYSA-N 1-phenoxy-3-piperidin-1-ylpropan-2-ol Chemical class C1CCCCN1CC(O)COC1=CC=CC=C1 QPMPQYGUAKDGAE-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 claims 12
- 125000003545 alkoxy group Chemical group 0.000 claims 7
- 239000000825 pharmaceutical preparation Substances 0.000 claims 7
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 6
- 229910052739 hydrogen Inorganic materials 0.000 claims 6
- 239000001257 hydrogen Substances 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 5
- 125000003342 alkenyl group Chemical group 0.000 claims 4
- 125000003302 alkenyloxy group Chemical group 0.000 claims 4
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 4
- 125000001589 carboacyl group Chemical group 0.000 claims 4
- 229910052736 halogen Inorganic materials 0.000 claims 4
- 150000002367 halogens Chemical class 0.000 claims 4
- 150000003053 piperidines Chemical class 0.000 claims 4
- XBDQKXXYIPTUBI-UHFFFAOYSA-N Propionic acid Substances CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims 3
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 claims 3
- 125000005236 alkanoylamino group Chemical group 0.000 claims 3
- 239000002220 antihypertensive agent Substances 0.000 claims 3
- 229940030600 antihypertensive agent Drugs 0.000 claims 3
- 239000002934 diuretic Substances 0.000 claims 3
- 230000001882 diuretic effect Effects 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- RPTUSVTUFVMDQK-UHFFFAOYSA-N Hidralazin Chemical compound C1=CC=C2C(NN)=NN=CC2=C1 RPTUSVTUFVMDQK-UHFFFAOYSA-N 0.000 claims 2
- 125000005133 alkynyloxy group Chemical group 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 1
- GXGJIOMUZAGVEH-UHFFFAOYSA-N Chamazulene Chemical group CCC1=CC=C(C)C2=CC=C(C)C2=C1 GXGJIOMUZAGVEH-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- VQKLRVZQQYVIJW-UHFFFAOYSA-N dihydralazine Chemical compound C1=CC=C2C(NN)=NN=C(NN)C2=C1 VQKLRVZQQYVIJW-UHFFFAOYSA-N 0.000 claims 1
- ACGDKVXYNVEAGU-UHFFFAOYSA-N guanethidine Chemical compound NC(N)=NCCN1CCCCCCC1 ACGDKVXYNVEAGU-UHFFFAOYSA-N 0.000 claims 1
- 229910052740 iodine Inorganic materials 0.000 claims 1
- 239000011630 iodine Substances 0.000 claims 1
- 230000003287 optical effect Effects 0.000 claims 1
- -1 p-Hydroxy-phenoxy Chemical group 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1253972A CH574953A5 (enrdf_load_stackoverflow) | 1972-08-24 | 1972-08-24 | |
| CH967073 | 1973-07-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL42976A0 IL42976A0 (en) | 1973-11-28 |
| IL42976A true IL42976A (en) | 1976-12-31 |
Family
ID=25705134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL42976A IL42976A (en) | 1972-08-24 | 1973-08-14 | 1-(3-phenoxy-2-hydroxy-1-propyl)piperidine derivatives,their manufacture and pharmaceutical compositions containing them |
Country Status (10)
| Country | Link |
|---|---|
| AR (3) | AR205881A1 (enrdf_load_stackoverflow) |
| DD (1) | DD107280A5 (enrdf_load_stackoverflow) |
| DK (1) | DK140143B (enrdf_load_stackoverflow) |
| EG (1) | EG11083A (enrdf_load_stackoverflow) |
| ES (1) | ES418099A1 (enrdf_load_stackoverflow) |
| FI (1) | FI57945B (enrdf_load_stackoverflow) |
| HU (1) | HU167727B (enrdf_load_stackoverflow) |
| IE (1) | IE38081B1 (enrdf_load_stackoverflow) |
| IL (1) | IL42976A (enrdf_load_stackoverflow) |
| NO (1) | NO138658C (enrdf_load_stackoverflow) |
-
1973
- 1973-01-01 AR AR24974973A patent/AR205881A1/es active
- 1973-07-17 FI FI225773A patent/FI57945B/fi active
- 1973-08-14 IE IE139473A patent/IE38081B1/xx unknown
- 1973-08-14 IL IL42976A patent/IL42976A/en unknown
- 1973-08-16 NO NO326273A patent/NO138658C/no unknown
- 1973-08-22 DD DD17302373A patent/DD107280A5/xx unknown
- 1973-08-22 ES ES418099A patent/ES418099A1/es not_active Expired
- 1973-08-23 HU HUCI001401 patent/HU167727B/hu unknown
- 1973-08-23 EG EG32573A patent/EG11083A/xx active
- 1973-08-23 DK DK465073A patent/DK140143B/da unknown
-
1975
- 1975-01-01 AR AR25864475A patent/AR207463A1/es active
- 1975-01-01 AR AR25864575A patent/AR207149A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| IE38081L (en) | 1974-02-24 |
| DK140143C (enrdf_load_stackoverflow) | 1979-11-19 |
| DK140143B (da) | 1979-06-25 |
| ES418099A1 (es) | 1976-06-16 |
| NO138658C (no) | 1978-10-18 |
| FI57945B (fi) | 1980-07-31 |
| NO138658B (no) | 1978-07-10 |
| AR205881A1 (es) | 1976-06-15 |
| DD107280A5 (enrdf_load_stackoverflow) | 1974-07-20 |
| HU167727B (enrdf_load_stackoverflow) | 1975-12-25 |
| IL42976A0 (en) | 1973-11-28 |
| AR207463A1 (es) | 1976-10-08 |
| AR207149A1 (es) | 1976-09-15 |
| EG11083A (en) | 1976-11-30 |
| IE38081B1 (en) | 1977-12-21 |
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