IL42933A - 2- Alcalamino dihydropyridines, their manufacture and pharmaceutical preparations containing them - Google Patents

2- Alcalamino dihydropyridines, their manufacture and pharmaceutical preparations containing them

Info

Publication number
IL42933A
IL42933A IL42933A IL4293373A IL42933A IL 42933 A IL42933 A IL 42933A IL 42933 A IL42933 A IL 42933A IL 4293373 A IL4293373 A IL 4293373A IL 42933 A IL42933 A IL 42933A
Authority
IL
Israel
Prior art keywords
ester
carbon atoms
compound according
acid
compound
Prior art date
Application number
IL42933A
Other languages
English (en)
Hebrew (he)
Other versions
IL42933A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL42933A0 publication Critical patent/IL42933A0/xx
Publication of IL42933A publication Critical patent/IL42933A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL42933A 1972-08-12 1973-08-09 2- Alcalamino dihydropyridines, their manufacture and pharmaceutical preparations containing them IL42933A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2239815A DE2239815C2 (de) 1972-08-12 1972-08-12 2-Alkylamino-dihydropyridine, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
IL42933A0 IL42933A0 (en) 1973-11-28
IL42933A true IL42933A (en) 1977-04-29

Family

ID=5853453

Family Applications (1)

Application Number Title Priority Date Filing Date
IL42933A IL42933A (en) 1972-08-12 1973-08-09 2- Alcalamino dihydropyridines, their manufacture and pharmaceutical preparations containing them

Country Status (29)

Country Link
US (1) US3959292A (ko)
JP (1) JPS5626660B2 (ko)
KR (1) KR780000072B1 (ko)
AT (1) AT327194B (ko)
AU (1) AU469267B2 (ko)
BE (1) BE803474A (ko)
BG (1) BG22816A3 (ko)
CA (1) CA1016945A (ko)
CH (1) CH583196A5 (ko)
CS (1) CS178892B2 (ko)
DD (1) DD109627A5 (ko)
DE (1) DE2239815C2 (ko)
DK (1) DK136062C (ko)
ES (1) ES417807A1 (ko)
FI (1) FI55998C (ko)
FR (1) FR2195450B1 (ko)
GB (1) GB1384219A (ko)
HU (1) HU167991B (ko)
IE (1) IE37989B1 (ko)
IL (1) IL42933A (ko)
LU (1) LU68206A1 (ko)
NL (1) NL7311031A (ko)
NO (1) NO139130C (ko)
PL (1) PL89396B1 (ko)
RO (1) RO62914A (ko)
SE (1) SE386164B (ko)
SU (1) SU475772A3 (ko)
YU (1) YU36172B (ko)
ZA (1) ZA735460B (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2639257A1 (de) * 1976-09-01 1978-03-02 Bayer Ag Aminoalkylidenamino-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4442100A (en) * 1979-12-11 1984-04-10 Bayer Aktiengesellschaft Substituted 2-amino-3,4-dihydropyridine derivatives, their production and their medicinal use
DE3134945A1 (de) * 1981-09-03 1983-03-17 Bayer Ag, 5090 Leverkusen Substituierte 2-amino-3,4-dihydropyridinderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimittel
EP0094159B1 (en) * 1982-05-10 1990-03-14 Takeda Chemical Industries, Ltd. Dihydropyridine derivatives, their production and use
US4603135A (en) * 1983-10-17 1986-07-29 Takeda Chemical Industries, Ltd. Substituted piperazinyl alkyl esters of 2-amino-4-aryl-1,4-dihydro-6-alkyl-3,5-pyridinedicarboxylates
US4678796A (en) * 1984-11-30 1987-07-07 Warner-Lambert Company 2-alkylidene derivatives of 1,2,3,4-tetrahydropyridine-2,5-pyridine carboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
CA1267416A (en) 1985-06-17 1990-04-03 Ila Sircar 1,4-dihydropyridine derivatives useful for the treatment of cardiovascular disorders
US4732898A (en) * 1986-04-29 1988-03-22 Warner-Lambert Company 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
JPWO2019124203A1 (ja) 2017-12-22 2020-10-22 東レ株式会社 テープ状プリプレグ及びその製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3441648A (en) * 1967-02-07 1969-04-29 Smithkline Corp Compositions and methods for lowering blood pressure with 1,4-dihydropyridines
DE1670827C3 (de) * 1967-03-20 1974-10-24 Bayer Ag, 5090 Leverkusen 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
DE1670824C3 (de) * 1967-03-20 1978-08-03 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridin-33-dicarbonsäurealkylester
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern
DE2013431C3 (de) * 1970-03-20 1979-12-20 Bayer Ag, 5090 Leverkusen 4-Azidophenyl-l,4-dihydropyridin-3,5-dicarbonsäureester

Also Published As

Publication number Publication date
DE2239815A1 (de) 1974-02-21
NO139130C (no) 1979-01-10
CA1016945A (en) 1977-09-06
DK136062C (da) 1978-01-09
YU36172B (en) 1982-02-25
ZA735460B (en) 1974-07-31
FR2195450A1 (ko) 1974-03-08
RO62914A (fr) 1977-11-15
PL89396B1 (ko) 1976-11-30
NO139130B (no) 1978-10-02
ES417807A1 (es) 1976-03-01
IE37989B1 (en) 1977-11-23
JPS5626660B2 (ko) 1981-06-19
JPS4945079A (ko) 1974-04-27
YU213373A (en) 1981-06-30
GB1384219A (en) 1975-02-19
LU68206A1 (ko) 1973-10-16
CS178892B2 (en) 1977-10-31
SE386164B (sv) 1976-08-02
DK136062B (da) 1977-08-08
KR780000072B1 (en) 1978-03-30
CH583196A5 (ko) 1976-12-31
FI55998B (fi) 1979-07-31
FI55998C (fi) 1979-11-12
BE803474A (fr) 1974-02-11
IE37989L (en) 1974-02-12
DE2239815C2 (de) 1983-02-10
IL42933A0 (en) 1973-11-28
FR2195450B1 (ko) 1977-09-09
HU167991B (ko) 1976-02-28
BG22816A3 (ko) 1977-04-20
SU475772A3 (ru) 1975-06-30
AU469267B2 (en) 1976-02-05
US3959292A (en) 1976-05-25
AT327194B (de) 1976-01-26
AU5912473A (en) 1975-02-13
DD109627A5 (ko) 1974-11-12
ATA707073A (de) 1975-04-15
NL7311031A (ko) 1974-02-14

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